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| Additional Information about Products Approved in Testing
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Nature Made® Herbs St. John's Wort 300 mg Supplement Standardized Extract (300 mg extract/tablet)
What it is:
St. John's Wort is an aromatic, perennial herb which blooms yellow flowers around the time celebrated as John the Baptist's birthday, June 24th, hence the name. The flowering tops are the part of the plant (Hypericum perforatum) that is used.
St. John's Wort has a popular history and use today for enhancing mood and emotional well-being. The mood-elevating effects of St. John's Wort were originally thought to be due solely to the active component, Hypericin, but Hypericin does not act alone. As with many herbal medicines, St. John's Wort relies on the complex interplay of many active constituents (e.g. xanthones and flavonoids) for its mood enhancement. St. John's Wort may also block the receptors that bind serotonin.
The recommended dosage for St. John's Wort is 300 mg of the dried leaf and flower extract standardized to at least 0.3% hypericin, 3 times a day. Since St. John's Wort has a very long half-life of about 25 hours, it can actually be dosed all at once for the same effect, and to increase compliance. People who tend to be sensitive to the sun (such as fair-skinned individuals), should be cautioned when taking St. John's Wort, or those individuals taking large doses of the herb should also be cautioned. In addition, St. John's Wort may have additive effects with SSRI's and other antidepressants, and should only be used at the same time if the person is under physicians care. St. John's Wort is also contraindicated in pregnancy because it may stimulate uterine contractions. More recently, it has been discovered that SJW may affect the Cytochrome P450 system, which is responsible for metabolizing various drugs or medications. Therefore, St. John's Wort may affect the metabolism of certain drugs such as: WARFARIN, DIGOXIN, THEOPHYLLINE, CYCLOSPORINE AND ORAL CONTRACEPTIVES. PATIENTS ON ANY MEDICATION SHOULD CHECK WITH THEIR PHYSICIAN OR HEALTH CARE PROFESSIONAL, BEFORE TAKING ST. JOHN'S WORT. Also, individuals taking St. John's Wort should use caution in consuming several foods that contain tyramine that also influence the P450 system — such as broccoli, red wine, dried cheeses, pickled herring, to name a few. St. John's Wort may be recommended as part of a daily regimen for Mood/Emotional Well-Being.
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Where to Buy:
Click here to search for a retailer nearest you.
Dosage and Direction:
Take one tablet three times daily with a meal (or as recommended by your health care professional). Keep bottle tightly closed and store in a cool, dry place. KEEP OUT OF REACH OF CHILDREN. Do not use if imprinted seal under cap is broken or missing.
Ingredients:
Powdered St. John's Wort Aerial Parts Extract (Hypericum perforatum), Cellulose, Croscarmellose Sodium, Magnesium Stearate.
Precautions:
Individuals who are sensitive to the sun, should use caution since St. John's Wort may cause increased photosensitivity. You should not take St. John's Wort if currently on a anti-depressant medication, unless under a physician's care. St. John's Wort should not be taken in pregnancy because it may stimulate uterine contractions. It is also not recommended in lactating women. St. John's Wort may affect the Cytochrome P450 system, and may affect the metabolism of certain drugs such as: WARFARIN, DIGOXIN, THEOPHYLLINE, CYCLOSPORINE AND ORAL CONTRACEPTIVES. PATIENTS ON ANY MEDICATION SHOULD CHECK WITH THEIR PHYSICIAN OR HEALTH CARE PROFESSIONAL, BEFORE TAKING ST. JOHN'S WORT. St. John's Wort Tablets are made to Nature Made's purity and potency standards.
Click Here for detailed information on all Nature Made supplements.
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