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Question: Can curcumin with black pepper extract cause constipation? I had this problem when taking a curcumin formula with piperine, but it resolved when I switched to a curcumin supplement without this added ingredient.
Answer: Black pepper extract (trademarked as Bioperine®), which contains a compound called piperine, is sometimes added to curcumin to increase its bioavailability. There does not appear to be any evidence that it causes constipation, or has other adverse effects, when taken in typical doses -- although there is a potential concern about taking piperine with certain medications. For more details, plus information about other bioavailability enhancers, and our tests and comparisons products, see the Turmeric and Curcumin Supplements Review >>