Our Members Asked:
Are CoQ10 and ubiquinol safe to take for a long period of time? Should I give it a rest period?

Answer:
Studies with CoQ10 have not shown serious adverse effects at moderate doses even when taken for several years — although it may be best to divide the dose over the course of the day. (For more information about CoQ10 dosages used for reducing statin-related muscle pain, congestive heart failure, migraines and other uses, see the Dosage section of the Review).
Also, be aware that CoQ10 and ubiquinol may affect your response to certain medications. For more details, see the Concerns and Cautions section of the CoQ10 and Ubiquinol Supplements Review.
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