Do I need to divide my daily 300 mg dose of CoQ10 into smaller doses, or can I take it all at once?
If the total daily dose exceeds 100 mg, it is better to take CoQ10 in two or three smaller doses, rather than in one large dose. Be aware that more moderate doses of CoQ10 (e.g. 100 mg per day) have been more helpful than higher doses in some situations, so be sure you really need 300 mg per day. Also, keep in mind that CoQ10 is best absorbed when taken with a meal that contains some fat or oils - with the exception of water-soluble formulas, which do not need to be taken with fat. For more about dosage and absorption of CoQ10 -- including absorption enhancers, as well as our tests of popular supplements, see the CoQ10 & Ubiquinol Supplements Review >>