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Product Review

Probiotic Supplements Review (Including Pet Probiotics)

Probiotics: See What They Really Contain and Our Top Picks

CL Answer

I have IBS and don't want to take medication if I can help it. I've heard that peppermint works for IBS, but is there good research to support this?

Information about using peppermint oil for irritable bowel syndrome (IBS), including clinical evidence, dosage, safety and more.

Peppermint Oil for IBS? -- Bottle of peppermint oil and capsules and peppermint leaf

CL Answer

Butyrate Supplements for Gut Health: Does butyric acid really work and is it safe?

Can butyrate supplements improve gut health or help reduce symptoms of irritable bowel syndrome (IBS) or Crohn's disease? Find out what the clinical evidence shows, learn about the different forms of butyrate, including sodium butyrate, calcium-magnesium butyrate, and tributyrate, and get details about products such as BodyBio Sodium Butyrate and Healus Complete Biotic Tributyrin, dosage, safety and cost.

Butyrate Supplements

Product Review

Prebiotic Supplements Review

You Can't Tell How Much Fiber Is Really In Most Prebiotics Without Testing

Prebiotics 2024 Expanded Review

CL Answer

Has the probiotic VSL#3 been changed or discontinued? Is Visbiome a good alternative?

Find out if the probiotic formula VSL#3 has been changed and how it compares with Visbiome. ConsumerLab.com's answer explains.

VSL #3 vs. Visbiome -- box of VSL#3 and Visbiome

CL Answer

What are the benefits of Daily Synbiotic by Seed Health? Does it do what it claims, and is it better than other probiotics and prebiotics?

Review of Daily Synbiotic by Seed, including information about the prebiotic and probiotic strains in the supplement, and whether there is evidence of benefit for the synbiotic.

Person pouring Daily Synbiotic capsules from container into other hand

Clinical Update

7/18/2023

Probiotic for IBS?

Did taking a probiotic further reduce symptoms of irritable bowel syndrome in people on a low-FODMAP diet? Find out in the IBS section of our Probiotics Supplements Review.

Also see: Do any supplements help for irritable bowel syndrome (IBS)?

Clinical Update

6/30/2013

Probiotic for Irritable Bowel Syndrome?

A popular probiotic given in a yogurt appeared to reduce symptoms in people with irritable bowel syndrome. However, people taking a yogurt without the probiotic did just as well, if not better, over time, raising doubt about the value of the probiotic. For more details, as well as test results and comparisons for 29 probiotic supplements, see the updated Probiotic Supplements Review >>

CL Answer

Can a probiotic help men with prostatitis?

Learn more about prostatitis, the effects of probiotics on prostatitis, and other natural treatments.

CL Answer

Do probiotics help with lactose intolerance?

Find out if probiotics can help with lactose intolerance. ConsumerLab's answer explains, including some foods that may cause fewer symptoms in the lactose intolerant.

Woman with Stomach Pain Holding Glass of Milk

CL Answer

Which supplements can cause diarrhea?

Can supplements like magnesium cause diarrhea? Find out which supplements may cause diarrhea, such as vitamin B12, curcumin, magnesium, vitamin C and fish oil.

Which supplements can cause diarrhea? -- Woman with gastrointestinal pain

CL Answer

Have you heard of the probiotic, Keybiotics? Does it do what it claims, and is it worth the money they charge?

Whole Body Research Keybiotics probiotic information, including its ingredients and possible cheaper alternatives.

Probiotics

CL Answer

How do I choose the best probiotic supplement? There are so many different strains of bacteria!

Information on how to choose the best probiotic supplement based on safety and our lab test on probiotic bacteria content.

Probiotic Supplements and Bottles Against Blue Background

CL Answer

Do any supplements help for ulcerative colitis?

Find out what supplements & vitamins can help with ulcerative colitis, such as VSL#3, curcumin, aloe or boswellia.

Woman Grabbing Stomach Due To Abdominal Discomfort

CL Answer

Which supplements and foods help relieve constipation and which can cause constipation?

Find out which supplements can cause constipation, including iron, calcium, protein powders and drinks and others. ConsumerLab.com's answer explains.

Which supplements can cause constipation? -- Woman with gastrointestinal pain

CL Answer

Which supplements help reduce flatulence (gas), and are there any that make it worse?

Find out which supplements may help reduce flatulence (gas), and learn which supplements or foods may worsen symptoms of flatulence.

Older woman sitting on her bed and holding her stomach due to gas and bloating

CL Answer

Do any supplements help for irritable bowel syndrome (IBS)?

IBS supplements may help reduce irritable bowel symptoms such as pain, diarrhea and constipation. Supplements include probiotics, melatonin, and flaxseed.

Supplements for IBS? -- Women With Stomach Pain

Product Review

Digestive Enzyme Supplements Review

Big Differences in Strength Found Among Digestive Enzyme Supplements. CL Tests Reveal Which Are Best.

Clinical Update

8/03/2021

Vitamin D for IBS?

Can vitamin D supplementation reduce the severity of symptoms in people with irritable bowel syndrome (IBS)? See what a new study found in the What It Does section of our Vitamin D Supplements Review. Also see our Top Picks for vitamin D.

Clinical Update

8/07/2021

Peppermint Oil for IBS?

Can peppermint oil supplements improve symptoms in people with irritable bowel syndrome (IBS)? See what a new study found in our updated article about Peppermint Oil and IBS.

Clinical Update

10/02/2021

Human Milk Oligosaccharides (HMOs) for IBS?

Are symptoms of IBS improved with use of human milk oligosaccharides (HMOs)? Find out what research suggests in our answer to the question: Do any supplements help for irritable bowel syndrome (IBS)?

Clinical Update

1/02/2011

Probiotics and Irritable Bowel Syndrome (IBS)

A recent study of children with IBS found that eight weeks of treatment with a probiotic greatly reduced the frequency and severity of abdominal pain. See the Probiotic Supplements Review for the type and dose of probiotic used and more >>

Clinical Update

12/17/2014

Probiotic Reduces GI Pain in IBS

A yeast-based probiotic was recently shown to significantly reduce abdominal pain and discomfort among people with irritable bowel syndrome (IBS). The most notable effect occurred after 4 weeks of use. Other studies, typically using bacterial probiotics, have also shown some benefit in IBS. For details, see the Probiotic Supplements Review >> 

Clinical Update

5/25/2014

Probiotic for IBS Symptoms

A recent study found that a multi-strain probiotic reduced certain symptoms of irritable bowel syndrome (IBS). Get the details, as well as our tests of probiotic products, in the updated Probiotic Supplements Review >> 

Clinical Update

3/02/2016

Probiotic Helps with IBS

A probiotic was found to improve many symptoms of irritable bowel syndrome in a recent study. Studies with other probiotics have also shown benefits, but be aware that the choice of probiotic seems to depend on the type of IBS. Get the details, as well as our quality ratings, in the Probiotic Supplements Review >>

Clinical Update

10/06/2015

Probiotic Improves IBS Symptoms

A probiotic significantly improved symptoms in men and women with a particular type of irritable bowel syndrome (IBS), according to a recent study. Get the details, including dosage, and our tests of popular products, in the Probiotic Supplements Review >>

Clinical Update

6/12/2018

Probiotic for IBS?

Studies have shown that certain probiotics help relieve symptoms of irritable bowel syndrome (IBS), although this can depend on the type of IBS. The most recent study focused on people with diarrhea-predominant IBS. Get the results in the What It Does section of the Probiotic Supplements Review. Also see our Top Picks among probiotics.

Clinical Update

9/04/2018

Glutamine for IBS?

Glutamine, an amino acid, plays a role in maintaining the digestive tract. Can taking it as a supplement help people with irritable bowel syndrome (IBS)? Find out what a recent study showed in the Glutamine section of the Muscle Enhancers Review.

Clinical Update

5/26/2017

Probiotic Reduces Depression in IBS

A probiotic significantly decreased depression in men and women with irritable bowel syndrome (IBS), according to a recent study. For details, see the "What It Does" section of the Probiotic Supplements Review >>

Clinical Update

6/03/2022

Digestive Enzymes for IBS?

Does taking digestive enzymes reduce symptoms of irritable bowel syndrome (IBS)? Find out in our updated Digestive Enzyme Supplements Review.

Clinical Update

2/02/2024

Probiotic for IBS?

Did a multi-strain probiotic improve symptoms of irritable bowel syndrome in a recent study? Find out in the Symptoms of IBS section of our Probiotics Supplements Review. Also find out which product containing this specific multi-strain probiotic was tested and Approved by ConsumerLab.

Product Review

Melatonin Supplements Review

Trouble Sleeping? See CL's Tests of Melatonin Supplements and Top Picks.

Melatonin Review 2024

Recalls & Warnings

March 01, 2023

Seller of Dr. Miller’s Herbal “Detox” Teas Warned by FDA for Drug Claims

On February 3, 2023, the FDA issued a warning letter to Jackson Health & Wellness Clinic after inspection of the company’s website found statements about the company’s Dr. Miller’s Holy Tea, Dr. Miller’s Super Holy Tea, Dr. Miller’s Ultimate Tea, Dr.

CL Answer

What are the health benefits of bovine colostrum and is it safe?

Bovine colostrum is promoted for boosting immunity, preventing and treating diarrhea, and improving gut health, but does it really work? See the clinical evidence for bovine colostrum, including doses that have been used, as well as safety concerns, cost considerations, and the difference between regular bovine colostrum and hyperimmune bovine colostrum.

Bovine colostrum powder and capsule supplements

Product Review

Lactose Intolerance Products Review (Lactase Enzyme Supplements and Lactose-Free Milks)

Choose the Best Lactase Enzyme Supplement and Lactose-Free Milk. Find a CL Approved Lactose Intolerance Product.

Lactase Supplements Reviewed by ConsumerLab.com

Product Review

L-Tryptophan and 5-Hydroxytryptophan (5-HTP) Supplements Review

Choose the Best L-Tryptophan and 5-HTP Supplements. CL Tests Identify High Quality L-Tryptophan and 5-HTP (5-Hydroxy-L-Tryptophan) at the Best Value.

L-Tryptophan and 5-HTP (5-Hydroxy-L-tryptophan) Supplements Reviewed By Consumerlab.com

CL Answer

What are the health benefits of manuka honey, and is it safe?

Manuka honey health benefits, how it differs from common, store-bought honey, safety, evidence for using manuka honey for wounds, sore throat and cough, constipation and more.

Health Benefits of Manuka Honey -- jar of manuka honey

Product Review

Lavender and Tea Tree Essential Oils Review

Oils Tested for Authenticity and Purity

Product Review

Iron Supplements Review (Iron Pills, Liquids and Chews)

See Which Iron Supplements Are CL's Top Picks for Different Needs

Product Review

Berberine and Goldenseal Supplements Review

Tests Reveal the Best and Worst Berberine and Goldenseal Products

Product Review

Psyllium Fiber Supplements Review

Find the Best Psyllium Fiber Supplement and Avoid Lead.

Psyllium Review 2024

Product Review

Aloe Juices, Gels, and Supplements Review

How Much Aloe is Really in Aloe Products? Find Out and See Our Top Picks.

Product Review

Joint Health Supplements Review (Glucosamine, Chondroitin, MSM, Boswellia, Collagen and Turmeric)

One-Third of Joint Health Supplements Failed to Pass Our Tests. See Which Passed or Failed, and our Top Picks.

Review of Supplements for Joint Pain

Product Review

Muscle & Workout Supplements Review (Creatine and Branched-chain Amino Acids)

Do Creatine and BCAAs Really Improve Strength and Recovery?

News Release

November 10, 2022

Best Probiotic Supplements Identified by ConsumerLab Tests

  White Plains, New York, November 10, 2022 — Probiotic supplements can be helpful in preventing or treating constipation, diarrhea, flatulence, vaginal infections, and other conditions, but with so many different products on the market, choosing the best one is no easy task.

CL Answer

Which supplements, foods or diet and lifestyle changes help relieve acid reflux (heartburn), and which worsen it?

Find out which supplements and foods can help relieve acid reflux, and which can make it worse.

Supplements Making Acid Reflux Worse -- Man with acid reflux pain

CL Answer

Which supplements and foods reduce or increase the risk of kidney stones?

Find out which supplements, foods and beverages may increase or decrease the risk of kidney stones, including information about potassium, calcium, choline, turmeric and curcumin, vitamin C, as well as foods and beverages such as green tea, lemon juice, orange juice, cranberry juice, chocolate and almonds.

Supplements for Kidney Stones

CL Answer

Is it better to take fish oil, flaxseed oil -- or both?

Fish oil and flaxseed oil -- how they are different, what they are used for, if and how they can help with arthritis, depression, lowering cholesterol & more.

Flaxseed Oil vs Fish Oil -- Omega-3 Supplements

News Release

October 28, 2022

Labels on Prebiotic Supplements Are Often Unreliable, Tests Show

  White Plains, New York, October 28, 2022 — Prebiotic supplements provide fiber that feed beneficial bacteria in the gut. However, recent ConsumerLab tests show that consumers often can’t rely on labels to know how much prebiotic fiber is really in products.

CL Answer

Do any supplements help reduce menstrual pain or symptoms of premenstrual syndrome (PMS)?

Find out which supplements help reduce premenstrual syndrome (PMS) symptoms, such as mood swings, pain, bloating, irritability and food cravings.

Woman in PJs Holding Stomach from Abdominal Pain

CL Answer

What is BPC-157, what is it used for and is it safe?

Find out about BPC-157, including what it's promoted for and if it is safe.

White capsules vials and a syringe on a blue background

CL Answer

Do any supplements help for restless legs syndrome?

Find out whether supplements or vitamins like iron, magnesium, vitamin E and others can help for restless leg syndrome (RLS). ConsumerLab.com's answer explains.

Supplements for Restless Legs Syndrome

CL Answer

Are There Supplements That Help Treat POTS (Postural Orthostatic Tachycardia Syndrome)?

Find out which supplements and lifestyle changes may be helpful for people with Postural Orthostatic Tachycardia Syndrome (POTS).

POTS

CL Answer

Which supplements can help treat anemia? Do any supplements cause a low red blood cell count?

Find out which vitamin and nutrient supplements can help prevent and treat anemia in people who are nutrient deficient and learn which supplements may cause low blood cell counts, especially when used in excess.

Woman holding various vitamins and supplements in her hands

CL Answer

I developed a rash soon after starting a probiotic. Is it possible to be allergic to probiotics?

Find out if probiotics can cause allergic reactions, including skin rashes, and why.

Young Woman Scratching Forearm

CL Answer

Can zuPOO and its primary ingredient, cascara sagrada, cleanse the gut, improve digestion and help with weight management?

zuPOO is marketed for gut support and as a colon cleanser for weight management. Find out if research supports these claims and if ingredients in zuPOO are safe.

zuPOO supplement bottle with white background

News Release

April 14, 2020

ConsumerLab Tests Reveal Best Probiotic Supplements and Those With Quality Issues

White Plains, New York, April 14, 2020 — Probiotic supplements may be helpful for conditions including antibiotic-associated diarrhea, irritable bowel syndrome, and respiratory infections.

CL Answer

What is GABA (gamma-aminobutyric acid)? Is it beneficial for stress, anxiety, insomnia or other conditions, and is it safe?

Find out about GABA (gamma-aminobutyric acid), including if it's beneficial for insomnia, epilepsy, stress and anxiety, high blood pressure and building muscle, and learn if taking GABA supplements is safe.

Older women sitting calmly on a couch with her hands behind her head and her eyes closed

News Release

May 02, 2018

Best Probiotic Supplements and Kombuchas? -- ConsumerLab Tests 41 Popular Products, Reveals Problems and Top Picks

White Plains, New York, May 2, 2018 — With so many different probiotic supplements on the market, each providing different amounts and strains of beneficial bacteria or yeast, choosing the right one can be an overwhelming task.

News Release

February 13, 2014

Calcium, Vitamin C, and Fish Oil Supplements Drop in Use, Probiotics Rise According to ConsumerLab.com Survey

White Plains, New York, February 13, 2014 — A recent survey of over 10,000 people who use dietary supplements shows that the use of calcium, vitamin C and fish oil supplements fell during 2013 while the use of probiotics increased.

News Release

August 31, 2012

ConsumerLab.com tests selenium supplements -- Finds one with less than 25% of listed amount

White Plains, New York, August 31, 2012 — ConsumerLab.com announced results today of its Product Review of Selenium Supplements. Among the supplements selected by ConsumerLab.com for testing, one was found to contain only 23.

News Release

February 09, 2012

Probiotics grow in popularity but don't always deliver on promises says ConsumerLab.com -- New report provides guidance to consumers

White Plains, New York, February 9, 2012 — Probiotic supplements and foods containing "friendly" bacteria or yeast have become popular options for people hoping to improve bowel function or boost immunity. But many customers are confused by the vast array of choices.

Recalls & Warnings

December 17, 2020

FTC Crackdown on Six Deceptive CBD Products

On December 17, 2020, the FTC announced that it is taking action against six companies for selling CBD products with unsupported and deceptive health claims that they can treat a variety of conditions, including cancer, heart disease, hypertension, Alzheimer's disease, and others.

News Release

November 16, 2009

ConsumerLab.com finds many probiotics don't deliver listed ingredients

White Plains, New York November 16, 2009 — Many probiotic supplements do not contain the number of viable organisms listed on their labels according to a new report from ConsumerLab.com.

Clinical Update

2/03/2021

Thiamin Deficiency from Bowel Disease

People with inflammatory bowel disease (such as Crohn’s or colitis) can develop thiamin (vitamin B-1) deficiency, which can lead to life-threatening brain injury, as noted in a recent review of 31 cases. Learn more about this and other causes of thiamin deficiency in the Thiamin section of our B Vitamin Supplements Review.

Clinical Update

9/22/2015

Probiotic Increases Bowel Movement Frequency

A certain probiotic increased the number of weekly bowel movements in healthy men and women who reported a low frequency. Get the details, including brand and dosage, plus our tests of popular products in the Probiotic Supplements Review >>

Clinical Update

3/25/2022

Psyllium for Uncontrolled Bowel Movements

Psyllium is commonly used as a laxative, but did you know it can also help people with uncontrolled bowel movements (fecal incontinence), as noted in recent, expert guidelines? Get the details in the What It Does section of our Psyllium Fiber Supplements Review. Also see our Top Picks among psyllium supplements.

Clinical Update

10/28/2022

Zinc Deficiency & Bowel Disease

A recent study showed zinc deficiency to be extremely common among people with Crohn’s disease and ulcerative colitis (the most common forms of inflammatory bowel disease or IBD). Find out more and if zinc supplements may help in the Zinc deficiency section of our Zinc Supplements Review.

Learn more about supplements for Crohn's disease and ulcerative colitis.

News Release

August 04, 2009

Most vitamin E supplements pass testing, but what seems natural may be synthetic according to ConsumerLab.com -- New review of vitamin E supplements, oils, and creams released today

White Plains, New York — November 16, 2009 — Many probiotic supplements do not contain the number of viable organisms listed on their labels according to a new report from ConsumerLab.com.

News Release

December 12, 2006

Probiotic supplements grow in popularity but viable bacteria missing in many — ConsumerLab.com cautions consumers to select probiotics carefully and store them properly

WHITE PLAINS, NEW YORK — DECEMBER 12, 2006 — Sales of supplements containing beneficial organisms (probiotics) have grown rapidly, but a new test report from ConsumerLab.com shows that 44% contained fewer viable organisms than claimed or generally known to be effective.

Recalls & Warnings

April 23, 2013

Seller of Digestion, Thyroid and Vitamin D Supplements Warned For Drug Claims

On November 5, 2012, the FDA issued a warning letter to The Women's Health Institute at Texas following a review of the company's various websites which found statements made about Digest + SEB, Iodine Plus 2, and D5000 Vitamin D dietary supplements to be drug claims.

Clinical Update

5/05/2023

Restless Leg Syndrome: GABA vs Gabapentin

One of these can help with restless leg syndrome, while the other doesn’t. Learn the difference in our GABA Supplements Review, which includes our Top Picks for GABA.

Also see our article about supplements for restless legs syndrome.

Clinical Update

7/13/2018

Melatonin and Restless Legs Syndrome

Taking a melatonin supplement can help some people fall asleep, but a study suggests that it may be a problem for people with restless legs syndrome. Get the details, and learn about potential side effects of melatonin in the Concerns and Cautions section of the Melatonin Supplements Review.

Clinical Update

3/02/2016

Ginseng for Metabolic Syndrome?

A study in men with metabolic syndrome found no benefit on blood sugar levels from taking ginseng, but a small increase in testosterone. Get the details about this and other uses for ginseng, as well as our quality ratings in the Ginseng Supplements Review >>

Clinical Update

6/09/2018

Magnesium & Metabolic Syndrome

A study shows that magnesium can significantly help some people suffering from metabolic syndrome (i.e., high blood sugar, high blood pressure, and related symptoms). Get the details in the What It Does section of the Magnesium Supplements Review. Also see our Top Picks among magnesium supplements.

Clinical Update

12/07/2021

Can Warm Coffee Trigger Burning Mouth Syndrome?

A member asked if anyone else had experienced "burning mouth syndrome" after drinking warm coffee. Find out if drinking coffee can trigger symptoms of this known condition in the Safety section of our updated article about Coffee and Heart Health.

Clinical Update

12/10/2021

Magnesium for Metabolic Syndrome?

Can magnesium supplementation lower blood sugar and blood pressure in people with metabolic syndrome? Learn what a new study found in the What It Does section of the Magnesium Supplements Review. Also see our Top Picks among magnesium supplements.

Clinical Update

1/11/2022

Ginkgo and Cistanche for Chronic Fatigue Syndrome?

Does supplementing with ginkgo and cistanche extracts help reduce symptoms of chronic fatigue syndrome? See what a recent study showed in our updated answer to the question: Which supplements help to improve energy and decrease fatigue?

Clinical Update

5/20/2022

Inulin for Constipation?

Can inulin increase bowel movements in people with constipation? Find out in our updated CL Answer about supplements for constipation.

Clinical Update

11/08/2022

Synbiotic for Constipation?

Can supplementing with a synbiotic (probiotic + prebiotic) increase bowel movements in children with constipation? Find out what research showed in our CL Answer about this brand of synbiotics.

Clinical Update

2/13/2024

Crohn’s Disease, Colitis & Key Nutrients

Experts are advising that people with inflammatory bowel disease, including Crohn’s disease and ulcerative colitis, be monitored for deficiencies in vitamin D and iron.

Also see our Top Picks among vitamin D and iron supplements.

Clinical Update

7/14/2020

Precaution When Taking Iron

Supplementing with iron can cause constipation and even bowel obstruction. Find how to reduce these risks when taking iron in the ConsumerTips section of the Iron Supplements Review. Also see our Top Picks for iron.

Clinical Update

8/16/2016

Inulin for Constipation

A small study among men and women with constipation found that inulin, a type of prebiotic, was able to modestly increase the frequency of bowel movements in men and women with constipation. For details, evidence for other uses of prebiotics and our tests of products, see the Probiotics Supplements Review >>

Clinical Update

10/24/2015

Probiotic Helps with Constipation

A recent study found that taking a particular probiotic twice a day after meals significantly increased the number of bowel movements in people with chronic constipation. For details about the probiotic and dose, see the Probiotic Supplements Review >>

Clinical Update

2/21/2015

Probiotic Prevents Bloating from Proton Pump Inhibitor (PPI)

Acid-blocking PPI drugs, such as Prilosec (omeprazole) and Protonix (pantoprazole) may cause people to experience bloating and other unpleasant bowel symptoms, possibly due to overgrowth of bacteria in the intestine. A recent study suggests that taking a probiotic may help prevent these symptoms from occurring. For more details, as well as our reviews of popular probiotics, see the Probiotic Supplements Review >> 

Clinical Update

8/14/2021

J&J Vaccine Blood Clot, Guillain-Barre Risk

How common are blood clots and low platelet counts or Guillain-Barre syndrome after the J&J vaccine?

Clinical Update

8/18/2023

Inositol for PCOS?

See if a panel of experts recently recommended inositol for PCOS (polycystic ovarian syndrome) in our article about Inositol for PCOS.

Clinical Update

6/17/2022

Supplements for POTS?

People with postural orthostatic tachycardia syndrome (POTS) experience a fast heart rate, dizziness, and other symptoms when standing. Can any supplements or lifestyle changes help? Find out in our answer to the question: Are there supplements that help treat POTS?

Clinical Update

10/18/2022

Fenugreek for PCOS?

Can supplementing with fenugreek extract improve symptoms of polycystic ovarian syndrome (PCOS)? Find out what a recent study suggests in our updated article about Supplements and PCOS.

Clinical Update

9/26/2023

Creatine for Post-COVID Fatigue?

Does supplementing with creatine reduce fatigue or other symptoms in people with post-COVID fatigue syndrome? Find out what a recent study showed in the Creatine - What It Does section of our Muscle & Workout Supplements Review. Also see our Top Picks for creatine.

Also see: How Should You Take Care of Yourself After You’ve Had COVID-19?

Clinical Update

7/11/2023

Arthritis Supplement May Have Caused Cushing Syndrome

We’ve added more information about the risks of a supplement for joint pain sold by Walmart. Get the details.

Clinical Update

8/04/2013

5-HTP Concern

Three cases of eosinophilia-myalgia syndrome (EMS) have been reported among people taking 5-HTP, a compound related to L-tryptophan. EMS is a debilitating immune condition which has occurred in people taking L-tryptophan, but there were no previous reports of it being caused by 5-HTP. Get the details in the the updated review article on L-Tryptophan and 5-HTP >>

Clinical Update

3/31/2013

More Iron, Less PMS?

A new study showed that women getting more iron had a significantly lower risk of suffering PMS (premenstrual syndrome) -- but not just any type of iron. Get the details, as well as our ratings of iron supplements, in the updated Iron Supplements Review »

Clinical Update

1/20/2013

More Probiotic Concerns

According to a published case report, two women recently developed a severely debilitating condition ("eosinophilic syndrome") two to four weeks after taking what appears to be the same "new" probiotic supplement. It's not yet known if these are isolated cases or are there more to come. For more information, see the recent update to the Probiotic Supplements Review >>

Clinical Update

1/23/2016

Vitamin D Reduces PMS Symptoms

A recent study found that taking vitamin D significantly improved symptoms of premenstrual syndrome (PMS) in young women who were deficient in vitamin D. Get the details in the Vitamin D Supplements Review >>

Clinical Update

5/24/2017

POTS and Thiamin

A small study among people who suffer from POTS (postural tachycardia syndrome) suggested that supplementing with thiamin (vitamin B-1) may help some. For details, see the Thiamin (B-1) section of the B Vitamin Supplements Review >>

Clinical Update

8/02/2017

Iron for Restless Legs

Iron supplementation may help to reduce the severity of restless legs syndrome (RLS) symptoms in people who have deficient or low levels of iron, according to guidelines from the American Academy of Neurology. For details, including dosage, see the "What It Does" section of the Iron Supplements Review, which also includes our tests and quality comparisons of products.

Clinical Update

2/10/2017

High-Dose Resveratrol Increases "Bad" Cholesterol

A study of middle-aged men with metabolic syndrome found that high doses of resveratrol increased levels of "bad" LDL cholesterol. Get the details in the "What It Does" section of the Resveratrol Supplements Review (which includes our tests of products) >>

Clinical Update

6/12/2019

Reaction to CoQ10 and Alpha-Lipoic Acid

An autoimmune syndrome possibly caused by CoQ10 was recently reported. It is similar to rare cases caused by alpha-lipoic acid. For details see the updates to the Concerns and Cautions sections of the CoQ10 and Alpha Lipoic Acid Reviews.

Clinical Update

6/18/2019

Melatonin for PCOS?

Can melatonin help women who suffer from polycystic ovary syndrome (PCOS)? See what a recent study found in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

9/29/2020

Vitamin D and PCOS

Can vitamin D improve symptoms of (polycystic ovary syndrome (PCOS)? Find out what a recent study showed in the What It Does section of Vitamin D Supplements Review. Also see our Top Picks for vitamin D.

Clinical Update

5/01/2021

Does Kefir Lower Cholesterol?

Can drinking kefir that contains probiotics, decrease LDL cholesterol or triglyceride levels in people with metabolic syndrome? See what a new study found the Cholesterol-Lowering section of our Probiotic Supplements Review. Also see our Top Picks among probiotic supplements and drinks.

Clinical Update

12/01/2018

Vitamin D for Restless Legs?

Does high-dose vitamin D help women and men with restless legs syndrome? Find out what a recent study reported in the What It Does section of the Vitamin D Supplements Review. (Also see our Top Picks for vitamin D.)

Recalls & Warnings

March 16, 2006

Garden of Life, Maker of Primal Defense, Settles FTC Charges

On March 9, 2006, The Federal Trade Commission (FTC) announced that an operation that marketed dietary supplements sold at Whole Foods Market, GNC, the Vitamin Shoppe, and on the Internet settled FTC charges that they made deceptive advertising claims about their supplements.

Recalls & Warnings

November 02, 2012

Maker of Joint Health, Blood Sugar, Prostate, Ginkgo Supplements and More Warned For Drug Claims, Misbranding and Adulteration

On September 10, 2012, the FDA issued a warning letter to Global Source Management & Consulting for making drug claims about the following dietary supplements: Scientific Joint Program capsules, Alpha Lipoic Acid, Healthy Blood Sugar Diabetic Support, Dr.

Recalls & Warnings

September 14, 2021

Seller of Lion's Mane, Other Mushroom Supplements Warned by FDA

On July 20, 2021, the FDA issued a warning letter to Brilliant Enterprises LLC because it found statements made on the company's website and social media about mushroom supplements, including Lion's Mane, BoomChaga, CordaCex, and LVL:MAX to be drug claims.

Recalls & Warnings

September 13, 2013

Metagenics Warned For Misbranding of Medical Foods and Drug Claims

On August 13, 2013, the FDA issued a warning letter to Metagenics, Inc.

Recalls & Warnings

February 22, 2021

FDA Warns Seller of Melatonin & Other Sleep Supplements

On February 18, 2021, the FDA issued a warning letter to SANA Group LLC following a review of the company's website, which found statements made about the company's products Sleep Sana Sleep Drops and Sleep Shots to be drug claims.

Recalls & Warnings

April 17, 2020

Seller of Vitamin D, MSM, Selenium & More Warned for Drug Claims

On March 31, 2020, the FDA issued a warning letter to KetoKerri LLC following a review of the company's website, which found statements made about some of the company's products, including Dr.

Recalls & Warnings

November 29, 2016

Seller of Mineral, Joint Supplements and More Warned for Manufacturing Violations, Drug Claims

On July 1, 2016, the FDA issued a warning letter to BioGenyx-Basic Reset, following a facility inspection which found the company's products, including Ionyte, Aqualyte, Beta Factor, Bee Gold and Primo Java to be adulterated because they were prepared, packed, or held under ...

Recalls & Warnings

October 24, 2012

Manufacturer of Green Tea, Vitamin E, Omega-3 and Cranberry Supplements Warned For Manufacturing Violations, Misbranding and Drug Claims

On October 16, 2012, the FDA issued a warning letter to dietary supplement manufacturer Advanced Nutritional Technology Inc.

Recalls & Warnings

December 21, 2012

Dangerous Supplement Being Sold Under New Name

On December 21, 2012, the FDA warned consumers that Reumofan Plus, a dietary supplement promoted for arthritis and muscle pain that has been linked to serious and sometimes fatal side effects, is now being sold under the name WOW.

Recalls & Warnings

August 22, 2012

FDA Warns of Life-Threatening Side Effects and Withdrawal Symptoms from Two Arthritis, Muscle Pain Supplements

On August 21, 2012, the FDA issued a warning to consumers about the dangers of taking Reumofan Plus and Reumofan Plus Premium, two dietary supplements marketed for arthritis, osteoporosis and muscle pain.

Recalls & Warnings

February 20, 2013

Recall: Arthritis and Muscle Pain Supplement Contains Prescription Drugs

On February 15, 2013, Reumofan Plus USA, LLC and Reumofan USA, LLC announced a recall of Reumofan Plus, a dietary supplement promoted for arthritis and muscle pain, because it was found to contain the active pharmaceutical ingredients methocarbamol, dexamethasone, and diclofenac.