Showing Results for Tryptophan (L-Tryptophan)
L-tryptophan and 5-Hydroxy-L-tryptophan (5-HTP)
Learn how to find the best L-Tryptophan and 5-Hydroxytryptophan (5-HTP) supplements, evidence for using L-tryptophan or 5-HTP for sleep, depression, migraine, and more. Plus, dosage, safety, side effects and potential drug interactions. Find out which L-Tryptophan and 5-Hydroxytryptophan (5-HTP) supplements passed our tests.
L-tryptophan and 5-Hydroxy-L-tryptophan (5-HTP) Review
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Clinical Update
11/20/2011
L-Tryptophan -- Still a Problem?
A woman in Illinois taking L-tryptophan for insomnia developed the same serious problems that resulted in L-tryptophan being temporarily removed from the market several years ago. Is L-tryptophan any safer now than it was before? For more information, see the update to the L-Tryptophan and 5-HTP Review Article.
CL Answer
Which vitamins and supplements should be stopped before getting blood work and laboratory tests?
Find out which vitamins and supplements can interfere with blood, urine or stool tests, and imaginging tests. Learn how B vitamins such as biotin, niacin and riboflavin, as well as calcium supplements, St. John’s wort, vitamin C, and others supplements can affect test results, as well as common foods that may interfere with tests.
Clinical Update
8/04/2013
5-HTP Concern
Three cases of eosinophilia-myalgia syndrome (EMS) have been reported among people taking 5-HTP, a compound related to L-tryptophan. EMS is a debilitating immune condition which has occurred in people taking L-tryptophan, but there were no previous reports of it being caused by 5-HTP. Get the details in the the updated review article on L-Tryptophan and 5-HTP >>
CL Answer
Which supplements and lifestyle changes improve sleep, and which cause insomnia?
Find out which vitamins may help you sleep and learn if any vitamins or supplements can cause insomnia.
Clinical Update
1/19/2019
Dog Overdoses on Supplement
Be sure to keep your supplements away from pets -- especially if they taste sweet. A dog overdosed on its owner's fast-dissolving tablets, putting it in a coma, according to a recent report. For details, see the Concerns and Cautions section of the L-tryptophan and 5-HTP Supplements Review.
Clinical Update
8/24/2021
Parkinson's Disease: 5-HTP for Sleep?
Can supplementation with 5-HTP reduce sleep disturbances in people with Parkinson's disease? See what a recent study found in the What It Does section of our L-Tryptophan and 5-HTP Supplements Review.
Also see our answer to the question: Do supplements help with Parkinson's disease treatment or prevention?
Clinical Update
11/08/2022
5-HTP for Sleep?
A CL Member asked how to use 5-HTP to improve sleep. Find out what research suggests in the 5-HTP section of our 5-HTP and L-Tryptophan and Supplements Review.
Also see our CL Answer about supplements and lifestyle modifications for insomnia.
News Release
July 31, 2018
Best L-Tryptophan and 5-HTP Supplements Identified by ConsumerLab -- ConsumerLab Tests Strength and Purity of Supplements for Sleep and Mood
White Plains, New York, July 31, 2018 — L-tryptophan supplements are often promoted to improve sleep and 5-HTP supplements to help with depression.
Product Review
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CL Answer
Which supplements may benefit people with essential tremor, and which should be avoided?
Learn about supplements used for treating essential tremor, including caprylic acid (also called octanoic acid), thiamin (vitamin B1), cannabidiol (CBD), GABA (gamma-aminobutyric acid), and branched-chain amino acids. Find out which work and which don't. Also find out which supplements and food may make essential tremors worse.
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CL Answer
What is the best way to take melatonin to get a good night's sleep?
Learn more about the best way to take melatonin for better sleep. When to take it, how to take it, and general melatonin information.
CL Answer
Do supplements help with Parkinson’s disease treatment or prevention?
Learn what has been shown with vitamins D and E, niacin, CoQ10, melatonin, creatine, SAMe, NAC, valerian, CoQ10, and CBD, as well as with coffee and the Mediterranean and MIND diets for treating and/or preventing Parkinson's disease.
Recalls & Warnings
February 22, 2021
FDA Warns Seller of Melatonin & Other Sleep Supplements
On February 18, 2021, the FDA issued a warning letter to SANA Group LLC following a review of the company's website, which found statements made about the company's products Sleep Sana Sleep Drops and Sleep Shots to be drug claims.
Recalls & Warnings
December 01, 2018
Seller of 5-HTP, Potassium & More Warned for Manufacturing Violations
On September 7, 2018, the FDA issued a warning letter to The Delano Company, Inc.
Recalls & Warnings
December 21, 2016
Seller of 5-HTP, Chromium, Curcumin and More Warned for Drug Claims
On December 1, 2016, the FDA issued a warning letter to Aurora Health and Nutrition following a review of the company's website, which found statements made about its products, 5-HTP, Alpha Lipoic Acid, the Argentyn 23 product line, Artecin 90 Vegetarian Capsules, ...
Recalls & Warnings
July 27, 2012
Prescription and Street Drug Alternatives Found in Male Enhancement, Mood, and Sleep Supplements
On July 10, 2012, the FDA issued a warning letter to Evol Nutrition Associates, Inc. subsequent to a 2011 inspection which found a number of the company's products contained prescription and investigational drugs and were misbranded.
