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Product Review: DHEA Supplements |
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HOW PRODUCTS WERE EVALUATED:
How Products were Selected:
Products were selected to represent those commonly available in the U.S. and Canada. ConsumerLab.com purchased products on the open market through retail stores, on-line retailers, and direct sales or multi-level marketing companies. Products were not accepted directly from manufacturers. For each product, the sample was composed of one or more purchased samples from a lot having an expiration date (if labeled) later than the date of testing.
Testing Method:
Products were tested for their ability to disintegrate, claimed amount of DHEA and for potential contamination with various anabolic agents. Analysis for DHEA was performed using by High Performance Liquid Chromatography (HPLC) method in an independent laboratory. Products not having passing levels of DHEA were then re-tested in a second independent laboratory an HPLC method. Screening for anabolic agents and related substances (see list below) was performed by Gas Chromatography and confirmed with Mass Spectrometry.
Anabolic agents and related substances for which products were tested:
androstenediol and analogs
androstenedione and analogs
clenbuterol
clostebol
fenoterol
fluoxymesterone
mesterolone
metandienone
metenolone (metheneolone)
methandriol
methyltestosterone |
nandrolone and analogs
19-norandrostenediol
19-norandrostenedione
norethandrolone
oxandrolone
oxymesterone
oxymetholone
stanozolol
testosterone and various salts
trenbolone |
Disintegration of non-chewable, non-capsule and non-time release formulations was analyzed utilizing USP (United States Pharmacopeia) 2040 recommendations entitled "Disintegration and Dissolution of Nutritional Supplements." Any product that did not pass the disintegration testing was sent to another independent laboratory in which the same test was repeated.
The identities of the products were not disclosed to the laboratories performing the testing.
Passing Score: *
To pass testing, a product had to:
- Have a minimum of 100% of its labeled amount of DHEA and a maximum of 125% of this amount.
- Meet recommended USP parameters for disintegration for dietary supplements (excluding capsule, chewable and time-release products).
- Contain less than 0.1% androstenedione (a manufacturing by-product of synthetic DHEA) and no other confirmed anabolic substance or related substance listed above.
* Passing scores allow for specific margins of technical error associated with each analysis.ConsumerLab.com reserves the right to disqualify a product at any time from passing its testing if it considers such product to present a safety risk or to provide misleading or inaccurate information in its labeling.
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