St. John's wort may be helpful in mild to moderate cases of clinical depression, but most of the herbal supplements that we purchased failed to meet quality standards. Two contained less St. John's wort compounds than claimed. Two others were contaminated with cadmium and/or lead. And three more lacked proper label information.
In this Review, you'll get ConsumerLab's test results for 14 St. John's wort supplements and information about two products similar to ones tested. We'll tell you what to look for and what to look out for, so you'll understand the potential benefits and risks of this popular herb.
You must subscribe to get the full test results and ConsumerLab recommendations. In this comprehensive report, you'll discover:
- Which products failed or passed our tests and why.
- What St.John's wort may do — and what it may not do.
- Suggested dosage from clinical studies.
- Cautions, important drug interactions, and potential side effects.

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