Schisandra Berry Supplements: Health Benefits and Safety

Medically reviewed and edited by Tod Cooperman, M.D.

Written by Amy Malec

Published August 18, 2025

Answer:

Schisandra berry supplements are often promoted for reducing stress and improving mood, boosting energy and "vitality," and supporting liver health.

The fruit or "berries" of the schisandra plant have been used in traditional Chinese medicine as an "adaptogen" to treat a wide range of conditions, and laboratory research suggests that polyphenolic compounds in schisandra fruit, have antioxidant, anti-inflammatory and anti-tumor effects, as well as protective effects on the liver and nervous system (Sowndhararajan, Biomed Pharmacother 2017).

But is there evidence that schisandra supplements really work, and are they safe?

Sign in as a member to learn about the clinical evidence for schisandra berry supplements and extracts for reducing stress, improving mood, sleep, memory, or liver health, increasing muscle strength, or reducing symptoms of menopause such as hot flushes, sweating, and palpitations. Also learn about the safety, side effects, and drug interactions with schisandra, and what to look for when choosing a schisandra supplement.

+ — 21 sources

In addition the results of its expert testing, ConsumerLab uses only high-quality, evidence based, information sources. These sources include peer-reviewed studies and information from agencies such as the FDA and USDA, and the National Academy of Medicine. On evolving topics, studies from pre-print journals may be sourced. All of our content is reviewed by medical doctors and doctoral-level experts in pharmacology, toxicology, and chemistry. We continually update and medically review our information to keep our content trustworthy, accurate, and reliable. The following sources are referenced in this article: