Product Reviews
NAC (N-Acetyl Cysteine) Supplements Review

Reviewed and edited by Tod Cooperman, M.D. Tod Cooperman, M.D.
 Initial Posting: 2/15/19  Last Update: 7/16/19
N-acetyl cysteine (NAC) supplements tested by

Choose the Best N-Acetyl Cysteine Supplement

See Our Tests of Popular NAC Supplements and Top Picks for Quality and Value

Alphabetical list of the NAC supplement brands compared in this review:
Carlson NAC NOW NAC Seeking Health NAC
Doctor's Best Best NAC Detox Regulators NutraBio NAC Solgar NAC
GNC NAC Nutricost NAC Vital Nutrients NAC
Life Extension N-Acetyl-L-Cysteine PharmaNAC  
Carlson NAC Doctor's Best Best NAC Detox Regulators GNC NAC Life Extension N-Acetyl-L-Cysteine NOW NAC NutraBio NAC Nutricost NAC PharmaNAC Seeking Health NAC Solgar NAC Vital Nutrients NAC
Find the right NAC supplement for you, at the right price! Isn't your health worth it?
NAC (N-acetyl cysteine) is a supplement which the body converts into glutathione, an important antioxidant. NAC is promoted for many uses. These include "liver support," "immune support," and reducing symptoms of the flu and flare-ups of chronic bronchitis and COPD. But is there good evidence for these uses, and for therapeutic uses for other conditions such as Sjogren's syndrome, renal failure, schizophrenia, compulsive behavior, and polycystic ovary disease? reviewed the clinical evidence for NAC. It also purchased and independently tested popular NAC supplements on the market, comparing their quality, dosage, and features, and cost.

Among the products that passed testing, the cost to obtain an equivalent dose (600 mg) of NAC ranged from just 4 cents to 63 cents -- meaning that you can save a lot by shopping wisely. Some products contain added ingredients, but it may not be worth paying more for these. We also found that the daily suggested dose ranged just 500 mg to 3,000 mg, so it's critical that you know how much you really need rather than rely on labels.

Based on its tests ConsumerLab selected Top Picks among NAC powders, capsules, and tablets based on quality, value, and other features.

You must be a member to get the full test results, along with ConsumerLab's recommendations. You'll get results for 11 NAC supplements -- eight selected by ConsumerLab and three others that passed the same testing through our voluntary Quality Certification Program.

In this comprehensive review, you'll discover:
    • Which NAC supplements passed or failed our tests
    • ConsumerLab's Top Picks for NAC — our selection of the best NAC powders, capsules and tablets based on quality, value, and special features
    • The evidence for or against NAC for different conditions
    • Why additional ingredients are sometimes added to NAC supplements and whether they matter
    • What "free form" NAC means and whether it's important to look for it on labels
    • Dosage of NAC for specific uses
    • Concerns, cautions, and potential side effects with NAC

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Learn More About N-Acetyl Cysteine Supplements: Answers -- for NAC (N-Acetyl Cysteine) Supplements Review
If I buy NAC as a loose powder in a large bag, as opposed to in tablet form, will it spoil? I've heard it can spoil or degrade into a harmful by-product. Get the answer >>

Is it true that NAC can help clear nasal passages? Get the answer >>

Which supplements reduce the risk of stroke? Which increase the risk of stroke? Get the answer >>

Do glutathione supplements work to prevent aging or for other conditions? Get the answer >>

Which supplements can help treat constipation? Get the answer >>

Which supplements can cause diarrhea? Get the answer >>

Can taking NAC (N-acetylcysteine) interfere with blood tests? Get the answer >>

Which supplements can cause constipation? Get the answer >>

Can taking N-acetylcysteine (NAC) supplements reduce my risk of liver damage from acetaminophen? Get the answer >>

What are natural remedies for coronavirus (COVID-19)? Do supplements like zinc, vitamin C, or herbals work? Get the answer >>
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