Answer:

Supplementing with creatine does not significantly affect creatinine levels (a measure of kidney function) nor creatine kinase (CK) activity (a measure of muscle breakdown) in most people. For details, see the Concerns and Cautions section of the Muscle & Workout Supplements Review, which covers ConsumerLab.com's tests and reviews of creatine supplements as well as branched-chain amino acid supplements.

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