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Older women sitting calmly on a couch with her hands behind her head and her eyes closed


GABA (gamma-aminobutyric acid) is a natural "inhibitory neurotransmitter," meaning it blocks impulses between the nerve cells, resulting in a calming effect. Many medications for insomnia, stress and anxiety, epilepsy, and other conditions work by affecting GABA activity. GABA also affects processes that control blood pressure and muscle mass, so it has been evaluated for hypertension and muscle building.

However, taking GABA orally does not increase GABA levels in the brain and has not been shown to provide benefit for epilepsy, insomnia or stress. There is mixed evidence as to whether GABA improves cognitive function. It may, however, affect blood pressure.

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May 19, 2021

I take 500 mg (or 250 mg) GABA to ease the symptoms of irritable bowl syndrome (IBS) when I eat food that triggers a reaction. It has approximately the same effect on me as the anti-anxiety medications Clonazepam or Gabapentin that I used to take for IBS, but, unlike those, GABA doesn't seem to cause habituation.

May 3, 2021

I have taken GABA off and on for several years for pain. I have various joint pains, due to arthritis and a deteriorated joint from to an old injury. It has worked quite well.

May 3, 2021

I have been using it for a few years. The calming support actually works!

Ruth Joshua22543
May 5, 2021

How much do you take for this support?

May 2, 2021

I started taking pharma GABA 100mg in the AM and 100 mg before bedtime. It definitely took the edge off of my stress. It didn't help with my sleep however! I still wake up between 4:30 and 5:30 AM.

May 25, 2021

Swanson CBD or 4mg of timed release melatonin help me stay asleep.

The CBD works better than the melatonin. I take 25mg 2 hours before bed and then another 5mg when I go to bed. Without that second dose I wake up too early.

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