ConsumerLab.com Answers  

Question:
Will pregnenolone help slow down aging?

Answer:
Pregnenolone is often called the "mother of steroid hormones" because it is a precursor to many other steroid hormones in the body.  Pregnenolone is naturally produced from cholesterol in the body and then it breaks down into other hormones including testosterone, estrogen, progesterone, DHEA, and others (see DHEA Supplements Product Review). 

Pregnenolone is also an ingredient found in a variety of products marketed as dietary supplements.  These supplements are typically promoted for aging, memory, reducing stress, premenstrual syndrome,  and others.   It is also often a component of "natural" or "bioidentical" hormone therapies used for menopausal symptoms (Boothby, Menopause 2004).

Proponents often recommend pregnenolone for signs of aging by suggesting that pregnenolone levels decline with age, along with many other hormones.  It is true that some steroid hormones , like DHEA, do decline with age, however, pregnenolone itself does not appear to significantly decline with age (Meldrum, Obstet Gynecol 1981).

To date, no clinical trials have evaluated pregnenolone in people for reducing the signs of aging or for other uses for which it is typically promoted.  

Since pregnenolone is a steroid hormone rather than a typical dietary nutrient, it should be used with caution.  Be sure to talk to your personal physician before taking it.

For more information, see the article about pregnenolone in the Encyclopedia on this website.



See other recent and popular questions >>
COMMENTS

Kevin8033   November 5, 2015
Why do you only cite one very old source to support your assertion that Pregnenolone does not decline with age? There are plenty of more recent scholarly sources to the contrary. Please check this.

When I paid for the subscription to Consumer Labs I was hoping for a full, balanced perspective the substances you review, but weakly cited claims make me feel like there is bias here.

Amy16221   November 20, 2017
Kevin.... You say "There are plenty of more recent scholarly sources to the contrary"..... however you didn't site any of them. That's why I trust Consumer Labs. Have a good day.


Share your thoughts and comments about this topic in the space below. Please abide by the following rules:
  • If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study.
  • If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product.
  • Please be respectful in your tone.
  • Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will comments that exceed 2,500 characters.
For your privacy, only your first name (from your account) followed by a random number will appear with your comment. Your last name and email address will not be displayed.
Comment:

Share your thoughts and comments about this topic in the space below. Please abide by the following rules:
  • If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study.
  • If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product.
  • Please be respectful in your tone.
  • Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will comments that exceed 2,500 characters.
For your privacy, only your first name (from your account) followed by a random number will appear with your comment. Your last name and email address will not be displayed.
Comment:

You can modify your comment below. Please be aware the comment will have to approve the changes before they will be shown:
Comment:

Your edit has been submitted and is being reviewed by ConsumerLab.com prior to publication.
This CL Answer initially posted on 5/17/2013. Last updated 8/8/2017.
ConsumerLab.com members may submit questions to CLAnswers@ConsumerLab.com. We read all questions and try to answer those of popular interest.

 

   BECOME A MEMBER
JOIN NOW


Product Reviews

ENCYCLOPEDIA
In addition to our product reviews our encyclopedia covers the following:

Herbs & Supplements

Conditions

Drug Interactions

Alternative Therapies

MEMBER TESTIMONIALS


Follow us on...
 
 
 
Join |  Sign In
   
Join Us on Facebook! Join Us on Instagram! Join Us on Twitter! Join Us on YouTube! Join Us on YouTube!
Product Tests
Brands Tested
Health Conditions
Encyclopedia
CL Answers
Clinical Updates
News
Recalls & Warnings
RDAs
Where to Buy Products
Raw Materials Tests
Testing Program
How Products Were Tested
Join CL Today
Testimonials
Join Free Newsletter
Group Subscriptions
Gift Membership
About Us
The CL Seal
CL Survey
Privacy Policy
Sitemap
Contact Us/Help

©2018 ConsumerLab.com, LLC. All rights reserved. A single copy of a report may be printed for personal use by the subscriber. It is otherwise unlawful to print, download, store or distribute content from this site without permission.
ConsumerLab.com name and flask logo are both registered trademarks of ConsumerLab.com, LLC. This site is intended for informational purposes only and not to provide medical advice.