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CL Answers (29)

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Recalls & Warnings (29)

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Clinical Updates (33)

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9/28/2021

Supplements During Chemotherapy?

If you are getting chemotherapy, experts now recommend avoiding acetyl-L-carnitine. Also, see what they have to say about using alpha-lipoic acid, vitamin B-12 and vitamin E.
1/08/2012

Additional Nutrients For the Brain

An new study found that various nutrients and fats in the blood correlate with better brain functioning and brain volume in the elderly (mean age of 87). Higher levels of B vitamins and vitamins C, D, and E, as well as marine omega-3 fatty acids (EPA and DHA) appeared helpful. On the other hand, higher levels of trans-fats (from hydrogenated oils) had a negative impact. You can learn more about each of these nutrients in our various reports. An abstract of the study is online.
8/02/2012

Vitamin E and Liver Cancer

A study has shown a dramatic decrease in the risk of liver cancer among people taking vitamin E supplements or getting higher amounts of vitamin E from their diets. But don't necessarily rush out to get vitamin E. Read the details in the update to the Vitamin E Supplements ReviewMore >>
4/30/2012

Cancer Findings with Natural Vitamin E

Clinical studies have raised doubts, and even concerns, about the relationship between vitamin E supplements and cancer. However, recent studies in animals suggest the tocopherols found in natural forms of vitamin E may help prevent cancer -- although the results are preliminary. For more about this, and our tests of vitamin E supplements, see the updated Vitamin E Supplements ReviewMore >>
10/23/2011

Vitamin E Risk

A study of healthy men who had taken a high-dose vitamin E supplement for several years showed a 17% increase in the risk of prostate cancer compared to men who took a placebo. See the Vitamin E Supplements Review for details, extensive information about vitamin E, and our quality ratings of vitamin E supplements.  More >>
1/04/2014

Vitamin E Helps Alzheimer's Patients

A new study suggests that high-dose vitamin E can help people with Alzheimer's disease retain their ability to perform activities of daily living (such as dressing) for several months longer than those given placebo, reducing caregiver time. A similar dose of vitamin E has been shown in other studies to slow the progression of the disease in some people and to reduce the rate of conversion to Alzheimer's among people with mild cognitive impairment. For details -- including the dose and form of vitamin E used and our tests of supplements on the market which can provide this dose -- see the update to the Vitamin E Supplements Review >>
2/07/2014

Vitamins C & E Blunt Exercise Effect

A recent study found that giving high-dose vitamin C or vitamin E to people involved in intensive exercise training blunted cellular changes thought to be important for improving muscular endurance. These and similar results recently reported with resveratrol raise concerns about high-dose antioxidant supplementation during exercise training. For details, see the updates to the "Concerns and Cautions" sections of the Vitamin C Supplements Review >>  and the Vitamin E Supplements Review >> 
2/27/2014

Vitamin E, Selenium Can Increase Cancer Risk

In some men, taking high doses of vitamin E or selenium may double the risk of developing high-grade prostate cancer, according to a recent analysis. For details, including the dose, see the updates to the Vitamin E Supplements Review >> and the Selenium Supplements Review >>   
9/19/2014

Can Vitamin E and/or Selenium Help Prevent Cataracts?

A study in older men in the U.S. found that taking large daily doses of vitamin E and/or selenium did not significantly reduce the risk of developing cataracts. But could the dose have been too high to be helpful? Other research has shown that "less is more" when it comes to antioxidant supplementation for cataracts. For more information, see the updates to the Vitamin E Supplements Review and the Selenium Supplements Review >> 
8/26/2015

Do We Need More Vitamin E?

A study recently suggested that many Americans don't get optimal intake of vitamin E from their diets. A closer look at this study, however, indicates that most people in the U.S. shouldn't worry. For details see the ConsumerTips section of the Vitamin E Supplements Review >>
6/10/2017

Hip Fracture Risk With Too Much B-6

A new study found that older men and women who took a high daily dose of vitamin B-6 had a 42% increased risk of hip fracture. Get the details in the "Vitamin B-6" section of the B Vitamin Supplements Review. Also, be aware that many supplements on the market contain the amount of B-6 used in this study, or more, in a daily serving! For help choosing a B-Complex or B-6 supplement that suits your needs without providing too much B-6, see our Top Picks among B vitamin supplements.
8/10/2021

Best Form of B-12 for Vegans?

What form of vitamin B-12 appeared best at raising B-12 levels among people on plant-based diets in a new study, and how did this compare to getting B-12 from plant-based foods? Find out in the B-12 section of our B Vitamin Supplements Review. Also see our Top Picks for vitamin B-12.
7/13/2021

Hidden Forms of B-12 Deficiency

Vitamin B-12 deficiency can occur even in people with "normal" blood levels of B-12, as was most recently reported in a 30-year-old man. Learn more, including the wide range of symptoms of B-12 deficiency and information about testing for B-12 deficiency in our B Vitamin Supplements Review. Also see our Top Picks for B-12.
6/27/2015

How Vitamin B-12 Causes Acne

Vitamin B-12 is a critical nutrient and many people, particularly those over 50, should supplement with B-12 to avoid deficiency. However, at doses higher than those used to prevent deficiency, B-12 may occasionally trigger acne. A new study appears to explain the B-12/acne connection. For details, see the "Cobalamin (B-12)" section of the B Vitamin Supplements Review >>
3/29/2017

Vitamin E/Selenium & Alzheimer's

A long-term study among men in the U.S. found that giving high doses of vitamin E and/or selenium did not significantly affect their risk of developing dementia. The study was part of a larger study which found that these supplements increased the risk of prostate cancer, type 2 diabetes, hair loss, and dermatitis. For details, see the "Alzheimer's disease/dementia" section of the Selenium Supplements Review >>
8/25/2020

B-12 Supplements vs. Injections

Can taking a B-12 supplement work as well as an injection to correct vitamin B-12 deficiency? See what a new study found in the B-12 section of the B Vitamin Supplements Review. Also see our Top Picks for vitamin B-12 and other B vitamin supplements.
11/29/2019

B Vitamins for Cognition

Increasing vitamin B-12 intake by those deficient in B-12 can help slow age-related declines in memory and cognition, but the dose needs to be sufficient, as suggested by a recent study. For details see the Memory, Cognition, and Alzheimer's Disease section of the B Vitamin Supplements Review. Also see our Top Picks for B-12 and other B Vitamins.
11/18/2020

B-12 for Singers

It is commonly believed that a shot of vitamin B-12 improves the performance of professional singers. A placebo-controlled study put this belief to the test. Get the results in the B-12 (cobalamin) section of our B Vitamin Supplements Review. Also see our Top Picks for B-12 and other B vitamins & complexes.
1/10/2017

Potential Risk with High B-12

Among people who are malnourished, those with elevated vitamin B-12 levels in their blood were twice as likely to die when hospitalized as those with lower B-12 levels, according to a new study. The study authors suggest caution with inappropriate supplementation. For more details about the study, and vitamin B-12, see the B Vitamin Supplements Review >>
11/04/2017

B Vitamins for Memory

Many studies suggest that adequate intake of B vitamins slows age-related declines in memory and cognition. This was recently shown again in a study in England. Find out which B vitamins help, and how much you need, in the "What It Does" section of the B Vitamin Supplements Review >> [Also see our Top Picks for B vitamin supplements in the Review.]
9/21/2013

B Vitamin Supplements for Stroke?

A review of 14 clinical studies suggests that B vitamins may help prevent stroke. However, a deep reading of the report shows the benefit to be slight, at best.  For details about the study, other uses of B vitamins (including B6, B-12, folic acid, niacin and complexes), and tests of these supplements, see the B Vitamin Supplements Review>>  
10/30/2011

B Vitamins May Help Memory

A recently published study of individuals aged 70 years or more with mild cognitive impairment found that a daily dose of three B vitamins (folic acid, vitamin B-12, and vitamin B-6) over 2 years appeared to slow cognitive and clinical decline, particularly in those who started with elevated levels of plasma homocysteine. See the B Vitamin Product Review for details including the dosage used.  More >>
12/23/2020

B-12 for Eczema?

Can vitamin B-12 deficiency worsen eczema and can supplementing with B12 help? Find out what happened in a recent case in the vitamin B-12 section of section of our B Vitamin Supplements Review. Also, see our Top Picks for vitamin B-12.
12/14/2013

B-12 Deficiency and Acid Inhibitors

A large, new study found the risk of vitamin B-12 deficiency to be significantly higher among people taking proton pump inhibitors (e.g., Prevacid, Prilosec) or H2-blockers (e.g., Pepcid, Zantac) than among those not taking these medications. The drugs reduce acid production in the stomach, but acid is needed to release B-12 from foods, so deficiency can occur. B-12 supplements can help because acid is not needed for their absorption. For details -- and our reviews of supplements with vitamin B-12 -- see the updated B Vitamin Supplements Review,   

For more information, see ConsumerLab's answer to the question, I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?.

11/16/2014

Do B Vitamins Boost Memory?

This week, a study was reported in the media suggesting that taking vitamin B-12 and folic acid does not help with memory. But a closer look at this and related studies shows a benefit for some people. Get the details, plus our tests and comparisons of B-vitamin supplements, in the B Vitamin Supplements Review >> 
10/09/2018

Can a B Vitamin Lower High Blood Pressure?

A common mutation of the MTHFR gene is associated with an increased risk of hypertension. A recent study tested whether supplementing with a specific B vitamin could reduce blood pressure in affected individuals. Get the results in the MTHFR section of the B Vitamin Supplements Review. (Also see our Top Picks among B vitamins.)
8/26/2017

High-Dose B Vitamins & Cataract Risk

Taking high doses of B vitamins, including B vitamin complexes, folic acid and B6, was associated with a higher risk of age-related cataracts among middle-aged men and women, according to a new study. For details, see the "ConsumerTips" section of the B Vitamin Supplements Review >>
6/12/2016

B Vitamins & Autism Risk

Excessive blood levels of B-12 and/or folate in pregnant women were found to be associated with an increased risk of autism in their children, according to a new study. While these vitamins are critical, too much may be problematic. Get the details in the B-12 and Folate sections of the B Vitamin Supplements Review >>
8/06/2020

B Vitamins and Fracture Risk

High homocysteine levels have been linked with increased fracture risk in older people. Taking B vitamins can lower homocysteine levels, but does it lower fracture risk? Find out what a recent study using folic acid and B12 showed in the What It Does section of the B Vitamin Supplements Review. Also see our Top Picks for B vitamins.
1/08/2012

B-12 and Folic Acid for Memory

Small but significant improvements in short and long-term memory were found to occur in older people (aged 60 to 74) given modest daily amounts of vitamin B-12 and folic acid. But don't expect immediate results. Improvements were seen only after 2 years of supplementation. See the update in the B Vitamins Review for the dosage used, as well as our ratings of supplements with vitamin B-12 and folic acid.
5/27/2013

Alzheimer's Changes Slowed with B Vitamins

A combination of B vitamins was found to slow brain loss in areas of the brain associated with Alzheimer's disease. This same combination of vitamins has also been shown to slow cognitive decline. Get the details on who may (or may not) benefit, dosage, plus test results for over 35 B vitamin supplements in the updated B Vitamin Supplements Product Review >>
8/14/2021

Danger With Too Much B-6

A CL member recently told us about a friend who developed progressively worsening neuropathy (nerve damage) after taking very high dose vitamin B-6. It's important to be aware of the upper daily limit for vitamin B-6 and that taking too much can cause nerve damage, as well as skin lesions and other adverse effects, as discussed in detail in our B Vitamin Supplements Review.
12/16/2012

Higher Vitamin Level May Slow Cognitive Decline

An 8-year study of people in their 70's found that cognitive functioning (memory and other mental skills) declined faster among those with lower blood levels of vitamin B-12 compared to those with higher levels. Particularly surprising was that 40% of the people in the study fell into the lower B-12 group, many of whom had levels which would not normally define them as deficient in B-12. This and other recent studies suggest a role for vitamin B-12 in minimizing cognitive decline in older people. For details, see the updated B Vitamin Supplements Review. More >>

News Releases (31)

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