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Posted January 16, 2014

Joint Health Supplement Contains Dangerous Drugs, FDA Warns

On January 15, 2014, the FDA warned consumers not to buy or use joint health supplement Pro ArthMax (by Human Science Foundation) because it was found to contain multiple drugs, including diclofenac, ibuprofen, naproxen, indomethacin, nefopam, and chlorzoxazone. These drugs can cause serious side-effects, and may increase the risk of serious side-effects in people who are taking other medications, especially anti-inflammatory drugs.

Diclofenac, ibuprofen, naproxen, and indomethacin are non-steroid anti-inflammatory drugs (NSAIDs), which can increase the risk of cardiovascular events and gastrointestinal damage, such as bleeding, ulceration, and fatal perforation of the stomach.

Chlorzoxazone is a prescription muscle relaxant which can cause drowsiness and dizziness, and may interfere with the ability to perform certain tasks such as driving or operating machinery.

Nefopam is non-narcotic pain relief drug that is not FDA-approved for marketing in the U.S. Rapid heart rate, sweating, dizziness, confusion, hallucinations, and seizures have been reported with the use of this drug.

Pro ArthMax is sold in some retail stores and on various websites, including It is also promoted to the Korean-speaking community (use the link below to the FDA's warning letter, which includes the Korean translation of Pro ArthMax's name).

It is labeled as containing methyl sulfonyl methane (MSM), Chinese boxthorn, Astragalus membranaceus, Cuscuta chinensis limak and Astracytlodes macrocephala.

Consumers who have purchased this supplement should discontinue use immediately and contact their healthcare provider if they have experienced any adverse side effects, including unusually dark stools or urine, stomach pain, increased bruising, other signs of bleeding, confusion, sedation, hallucinations, and seizures. Consumers and healthcare providers are also encouraged to report any adverse reactions to the FDA's MedWatch Adverse Event Reporting Program.

See's Review of Joint Health Supplements for tests of related products.

See Related Warnings:

FDA Warns Consumers of Supplement Containing Prescription Anti-Inflammatory Drug

Recall: Arthritis and Muscle Pain Supplement Contains Prescription Drugs

Dangerous Supplement Being Sold Under New Name

FDA Warns of Life-Threatening Side Effects and Withdrawal Symptoms from Two Arthritis, Muscle Pain Supplements

FDA Warning on Supplement for Pain Relief

To read the FDA's warning, use the link below.