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Posted October 09, 2014

New Synthetic Stimulant Found in Supplements

A synthetic stimulant never before studied in humans, 1,3-dimethylbutylamine (DMBA), was found in a dozen supplements sold by U.S. distributors in dosages from 13 to 20 mg per serving (Cohen, Drug Test Analys 2014).

DMBA is an analogue of the pharmaceutical stimulant, 1,3-dimethylamylamine (DMAA), which was recently banned by the U.S. Food and Drug Administration. Supplements containing DMBA are marketed to improve athletic performance, increase weight loss and enhance brain function.

Authors of the recent report suggest that regulatory agencies should act expeditiously to warn consumers and remove DMBA from all dietary supplements. They note that 3 cases of adverse events have been reported in Europe with a supplement found to contain DMBA sold as "Unstoppable" by Dedicated. Symptoms reported by users were similar and included the feeling of rushing, difficulty sitting still, a sense of motion and increased focus, although it is not known if DMBA was responsible for the adverse effects.

The supplements recently found to contain DMBA in the U.S. are Contraband, Redline White Heat, Evol, Preamp by Hybrid, OxyphenRX AMP'D, OxyTHERM Pro, AMP Citrate, Oxyfit Xtreme, Synetherm, AMPitropin, Decimate Amplified, AMPilean, and Frenzy.

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