On April 7, 2026, the FDA warned consumers not to purchase or use eight supplements labeled as containing hyaluronic acid and promoted for pain relief because they contain undeclared drugs. FDA testing showed that the supplements contained drugs such as diclofenac, dexamethasone, methocarbamol, meloxicam, phenolphthalein, and/or other drugs that are not listed on the label and are not permitted in dietary supplements.

(See ConsumerLab’s Review of Joint Health Supplements for tests of related products and our Top Picks.)

The supplements were sold on various websites and possibly in some retail stores. Use the links below for more details about each product:

• Curcuflex
• DINA Ácido Hialurónico
• Kuka Flex CBD
• Umary
• RM Joe
• Yeicob Ácido Hialurónico
• Flexi Bion
• Dolotrex

Diclofenac is a prescription non-steroidal anti-inflammatory drug (NSAID) that can cause serious cardiovascular events such as heart attack or stroke, as well as bleeding, ulceration, and fatal tears of the stomach and intestines, or liver toxicity. Diclofenac may also interact with other medications and significantly increase the risk of adverse events.

Dexamethasone is a prescription corticosteroid drug that has the potential to cause severe and serious adverse events, including adrenal suppression, a disorder in which the adrenal glands do not produce enough hormones, and other adverse events, which can lead to death. Sudden discontinuation of dexamethasone can also cause potentially dangerous withdrawal symptoms.

Methocarbamol is a prescription muscle relaxant that can impair a person’s ability to fight infections and can cause dizziness, low blood pressure, and sedation. Phenolphthalein, once an ingredient in some over-the-counter laxative products, was reclassified by the FDA in 1999 as "not generally recognized as safe and effective."

The FDA warns that suddenly stopping some of these drugs found in these supplements can cause adverse effects. Consumers and healthcare providers are advised to report adverse reactions to the FDA’s MedWatch Voluntary Reporting Program by fax, mail, or online.

For more information about this warning, use the link below:

FDA Warning: Hyaluronic Acid Products Containing Undeclared Ingredients

See related recalls and warnings:

Umary Joint Pain Supplements Recalled

Umary Hyaluronic Acid Sold on Amazon Recalled

Don’t Buy or Use Umary and Amazy Supplements, Warns FDA