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Drug Investigation: Toprol XL vs. Generic Metoprolol Succinate Extended-release (ER) Tablets
 

Initial Posting: 3/17/08  Last Update: 12/31/08    
Some generic blood pressure medications are not the same as the original drug. They may increase blood pressure and cause disturbing side-effects.

Find out which brands may be better for you. Your health could depend on it.
  

Brands of metoprolol succinate (generic Toprol XL) investigated in this report:

Make sure the medicine you take is equivalent to the brand name drug! Isn't your health worth it?
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Serious problems have been reported by some people switched from the popular blood pressure medication Toprol XL to generic versions. These problems include increased blood pressure, increased heart rate, hives and migraine headache.

ConsumerLab.com investigated the products on the market. What we found will shock you. Certain generics contain very different ingredients from Toprol XL. And these generics seem to differ from Toprol XL in how they dissolve – which may affect the rate at which they are absorbed in your body.

If you or a loved one uses generic Toprol XL, you need to know how the generics differ. In this Review, you'll get the results of ConsumerLab's investigation. You must subscribe to get the full report in which you'll discover:
    • Which generics are truly identical to original Toprol XL and which are not.
    • What these differences can mean to you.
    • A list of the generic products by distributor and manufacturer -- to help you tell them apart.
    • Strategies and tips on getting the right drug, as well as the names of pharmacies that carry each generic brand.
If you already are a subscriber, SIGN IN now.
Update:
In January 2009, the manufacturer of four strengths of generic Metoprolol Succinate ER tablets issued a recall due to manufacturing problems.  In August 2008, the U.S. FDA sent a Warning Letter to another manufacturer of Metoprolol Succinate ER tablets regarding violations in manufacturing -- resulting in later recalls but with little public announcement.  See the Updates section of the report for more information.
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