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CL Answers (30)

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Recalls & Warnings (102)

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Clinical Updates (33)

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Saw Palmetto May Not Work

It's used by many men hoping to reduce urinary symptoms caused by benign growth of the prostate, or BPH, but a new, well-designed study suggests that it doesn't work. Some other recent research suggest the same. Even when doubling and tripling the standard dose, the high-quality saw palmetto extract used in the new study failed to provide benefit.

What should you do? You may want to consider a different supplement -- beta-sitosterol, a phytosterol. The evidence remains fairly good for beta-sitosterol. To find out more about saw palmetto, beta-sitosterol, and the supplements we have tested, see the Prostate Supplements ReviewMore >>

Saw Palmetto for Prostate?

A recent clinical study is the latest to evaluate the potential benefit of saw palmetto in reducing symptoms of benign prostatic hypertrophy (BPH) in men. Find out what this, and previous studies, have shown in the What It Does section of the Prostate Supplements Review. Also see our Top Picks for saw palmetto and beta-sitosterol supplements.

Green Tea "Blocks" Beta-Blocker

A new study shows that drinking green tea can drastically reduce the amount of a beta-blocker (nadolol, Corgard) absorbed into the bloodstream. Beta-blockers are typically taken to lower blood pressure, raising concern for people using green tea along with this beta-blocker and, possibly, related medications. Get the details, along with our tests of green tea drinks and supplements, in the update to the Green Tea Review >>   

If you take a beta-blocker (which includes the popular drugs metoprolol (Lopressor, Toprol) and propranolol (Inderal)), be aware that chromium and CoQ10 may offer benefits.

Men's Health Supplements Don't Help Prostate Cancer

While there is some evidence that certain supplements may help relieve symptoms of prostate enlargement (BPH), a recent study shows no benefit with regard to prostate cancer treatment. Details are in the Prostate Supplements Review >>

Soy Protein to Prevent Prostate Cancer?

Prostate cancer occurs less frequently in parts of the world where people eat more soy. So researchers recently gave a soy protein drink, or a placebo drink, to men who previously had prostate cancer to see if it reduced the risk of the cancer recurring. Learn what they found in the updated Protein Powders and Drinks Review >>

Antioxidants: Too Much of a Good Thing?

A new, long-term study of Americans found the risk of dying over the course of the study (about 14 years) was lowest when antioxidant levels in the blood were above the lowest levels (the bottom 20% of the population). However, for people in the top 20% of blood levels for vitamins A and E, the risk of death increased compared to people with moderate levels. For selenium and beta-carotene, there was no significant difference in the death rate between moderate and high levels, although for vitamin C some additional benefit was seen at high, but not the highest, levels.
The results suggest that antioxidant supplements may be useful for those who are nutritionally deficient, but, as noted by the researchers, "beyond a certain threshold, higher levels do not lead to additional benefit, and may potentially be toxic." More details (including specific serum levels) are found in the linked updates to the following reviews, which include our test results and quality ratings of products:

Vitamin D and Prostate Cancer

A recent study looked at the association between vitamin D blood levels and the risk of advanced prostate cancer. Based on the findings from this and related studies, there seems to be a reasonable approach with vitamin D to potentially lower prostate cancer risk. Get the details (as well as our tests of products) in the Vitamin D Supplements Review >>

Latest Supplement Recommendations

New draft recommendations on vitamin and mineral supplement use were published this week by the U.S. Preventive Services Task Force. The recommendations apply only to healthy adults without nutritional deficiencies. They focus only on the use of supplements for the prevention of cardiovascular disease and cancer at doses not exceeding tolerable upper intake levels. The recommendations are based on existing science and are generally consistent with information already presented in's Product Reviews.  We have summarized the recommendations below, with links to more information in's reports:

- Beta-Carotene and Vitamin E:  Supplementation with either does not provide a benefit. Vitamin E does not pose a risk of harm, but beta-carotene increases the risk of lung cancer in people at risk for lung cancer.

- Other Single Vitamins, Minerals, Pairs, and Multivitamins: There is inadequate evidence regarding a benefit or a risk of harm.

The task force stressed that at excessive doses (above tolerable upper intake levels) there is evidence of harm with supplementation, such as with vitamin A and vitamin D

Vitamin D Deficiency May Predict Advanced Prostate Cancer

According to a new study, prostate biopsies in men who are deficient in vitamin D are more likely to show a higher grade and stage of cancer than biopsies in men with higher levels of vitamin D. For more details, as well as our tests of vitamin D supplements, see the Vitamin D Supplements Review >> 

Did you hear that DHA (an omega-3 fatty acid in fish oil) might raise the risk of prostate cancer?

This was recently in the news. Higher levels of DHA in the blood were associated with increased risk of high-grade prostate cancer. However, the findings do not mean that you should stop taking fish oil or eating fish. We talked with the researcher of this study and learned more. Get the facts in our Fish Oil Supplements ReviewMore >>

Fish Oil Linked to Prostate Cancer?

Headlines this week about a study showing an association between the fatty acids in fish oil and the development of prostate cancer have stirred concerns about consuming fish and fish oil supplements. For details about this study and studies of other effects of fish oil and omega-3 fatty acids, as well as test results and comparisons for 74 fish and other marine oil supplements, see the updated Fish/Marine Oil (Omega-3) Supplements Review >>

Selenium and Prostate Cancer

A new study suggests that men who have prostate cancer should not take supplements providing high-dose selenium. Earlier research has similarly advised against high-dose selenium for people with already adequate selenium intake. For details and more about selenium, see the Selenium Supplements Review >> 

Green Tea Extract and Prostate Cancer

A new study, funded by the National Institutes of Health, showed that fewer men with pre-cancerous lesions developed prostate cancer if given a daily green tea extract supplement, although the results were not statistically significant due, in part, to the small size of the study. However, a somewhat similar study found a significant benefit. Learn more about these studies, and see our test results for green tea supplements, teas, and drinks, in the Green Tea Review >>

Football & Vitamin D

The outcome of today's Super Bowl 50 may be influenced by players' levels of vitamin D. Several studies show that having the right amount of vitamin D in the body reduces the risk of falls in the elderly, but research also shows benefits for younger adults — including fewer injuries among NFL football players. Get the details in the Vitamin D Supplements Review and enjoy the game!

Saw Palmetto for Prostate?

Saw palmetto extract was once popular for reducing symptoms of prostate enlargement, but studies subsequently failed to find a benefit. A recent study assessed whether it could boost the effectiveness of conventional medical treatment. Get the results in the What It Does section of the Saw Palmetto Supplements Review.

Green Tea & Prostate Cancer

A recent study investigated the effects of green tea extract in men with pre-cancerous changes of the prostate. Find out if it helped in the "What It Does" section of the Green Tea Supplements and Drinks Review >>

Vitamin C and Prostate Cancer

Does taking vitamin C reduce the chance of developing prostate cancer? Find out what studies are showing, including one reported this month, in the What It Does section of the Vitamin C Supplements Review. (Also learn about vitamin C and cataracts and see our Top Picks for vitamin C.)

Olive Oil and Prostate Cancer

Another possible benefit of olive oil within a Mediterranean diet is a reduced risk of aggressive prostate cancer, according to a new study. For details about this and other benefits of olive oil, see the updated "What It Does" section of the Extra Virgin Olive Oils Review, which includes our Top Picks among products.

Coffee and Prostate Cancer Risk

Is drinking coffee associated with prostate cancer risk? Find out what a recent study suggests in our updated answer to the question: Does drinking coffee increase or decrease the risk of cancer? Can it slow cancer progression?

Curcumin & Prostate Cancer

Does curcumin benefit men undergoing chemotherapy for prostate cancer? See what a new study found in the What It Does section of our Turmeric and Curcumin Supplements & Spices Review. Also see our Top Picks among turmeric and curcumin products.

Don't Take Minerals With Certain Supplements

Taking minerals like calcium and magnesium can dramatically reduce the absorption of carotenoids like lycopene, beta carotene, and astaxanthin. Get the details in the Concerns and Cautions section of the Lycopene Supplements Review.

Caution With Antioxidants

A new study suggests it might be risky to take antioxidant supplements during cancer treatment. We have added this important information to our answer to the following question: Can supplements with antioxidants like beta-carotene and vitamins A and E cause you to die sooner?

Lower Melanoma Risk with Vitamin A

A study of people ages 50 to 76 found the risk of developing melanoma (over an average of 6 years) was 40% lower among those who took a vitamin A supplement than among those who did not. The protective effect appeared strongest and most statistically significant among women, and only occurred with vitamin A from retinol and, not beta-carotene. For details, including the dose (which matters), see the updated information in the Vitamin A Supplement ReviewMore >>

Saw Palmetto Concern

Does saw palmetto cause sexual dysfunction? Get the details in the updated Concerns and Cautions section of our Prostate Supplements Review.

Vitamin E Risk

A study of healthy men who had taken a high-dose vitamin E supplement for several years showed a 17% increase in the risk of prostate cancer compared to men who took a placebo. See the Vitamin E Supplements Review for details, extensive information about vitamin E, and our quality ratings of vitamin E supplements.  More >>

Does folic acid affect the risk of colon cancer?

Supplementation with higher amounts of folic acid (vitamin B-9) has been shown to increase the risk of prostate cancer, but its effect on the risk of colon cancer has been unclear. A new study found no increase in colon cancer due to folic acid supplementation. But if you supplement with folic acid, be careful. See the B Vitamin Supplements Review for more >>

Pomegranate for Memory?

Pomegranate juice and supplements have been promoted for improving cardiovascular health, controlling blood sugar, and inhibiting prostate cancer. Most recently pomegranate juice was tested in a year-long study for its effects on memory. Find out if it helped, and see if it works for other touted uses, in the What It Does section of the Pomegranate Juice and Supplements Review Article.

Pycnogenol for Prostate?

Pycnogenol, a branded form of pine bark extract, is promoted for a variety of uses, including improvement of circulation, cognition, joint pain and vision. It was recently given to men with benign prostatic hyperplasia (BPH) to see if it would improve urinary symptoms. Find out if it worked, and learn if it helps with other conditions, in our updated answer to the question: What is Pycnogenol and does it work? >>

Cranberry for Cystitis in Men?

Cystitis (inflammation of the bladder) is common in men undergoing radiation therapy for prostate cancer. A study evaluated whether a cranberry supplement could reduce the incidence of cystitis in these men. Find out if it helped in our updated answer to the question: Are cranberry supplements helpful for men? Can they help with symptoms of prostatitis or urinary tract infections?

Vitamin E, Selenium Can Increase Cancer Risk

In some men, taking high doses of vitamin E or selenium may double the risk of developing high-grade prostate cancer, according to a recent analysis. For details, including the dose, see the updates to the Vitamin E Supplements Review >> and the Selenium Supplements Review >>   

Fish Intake and Breast Cancer Risk

Women with breast cancer who consumed the most fish had a lower risk of death compared to women who did not eat fish, a new study reports. Get the details, plus evidence for the use of fish oil supplements to reduce the risk of breast and prostate cancer, and our tests of popular products in the Fish Oil and Omega-3 Fatty Acids Supplements Review >>

Vitamin E/Selenium & Alzheimer's

A long-term study among men in the U.S. found that giving high doses of vitamin E and/or selenium did not significantly affect their risk of developing dementia. The study was part of a larger study which found that these supplements increased the risk of prostate cancer, type 2 diabetes, hair loss, and dermatitis. For details, see the "Alzheimer's disease/dementia" section of the Selenium Supplements Review >>

Trouble Reported With Saw Palmetto

A 64 year-old man developed pancreatitis and heart block (dangerously slow heart rate) after supplementing with saw palmetto, according to a recent report. For details, see the "Cautions and Concerns" section of the Prostate Supplements Review >>

News Releases (26)

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