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Product Review

SAMe (S-adenosyl-methionine) Supplements Review

Choose the Best SAMe Supplement. CL Tests Reveal Big Differences in Quality and Cost.

Sam-e supplements reviewed by

News Release


SAM-e Supplements Providing Best Quality and Value Identified by

White Plains, New York, January 19, 2016 — SAM-e (S-adenosyl-methionine) is involved in the functioning of every cell in the body and, as a supplement, it has been found to be helpful in reducing the pain of osteoarthritis as well as improving mood in major depression.

News Release


30% of SAM-e supplements selected for review fail to pass testing -- Cost of SAM-e found to vary 5-fold

White Plains, New York, October 13, 2011 — Dietary supplements with SAMe (S-adenosyl-methionine) are used to treat osteoarthritis as well as depression, but only 7 out of ten SAM-e supplements recently selected for testing by met all quality criteria.

News Release

4/24/2007 reports improvement in quality of SAM-e supplements used for osteoarthritis and depression — Recent testing shows quality is up since studies in 2000 and 2003

WHITE PLAINS, NEW YORK — April 24, 2007 — announced that all eight SAMe supplements that it recently selected for review passed quality testing — an improvement over tests in previous years. SAMe (S-adenosyl-methionine) is used to treat depression and joint pain.