Does urolithin A reduce age-related muscle decline, osteoarthritis, or other age-related diseases?

Answer:

Urolithin A is a natural compound formed by the bacteria in the colons of many people after consuming certain foods. Urolithin A seems to improve the function of mitochondria (the "powerhouses" inside our cells). However, clinical research with urolithin A has suggested only limited benefit in improving muscle health in active young adults or middle-aged and older adults. Urolithin A has also been touted for treating osteoarthritis (painful, worn joints), preventing kidney damage, and preventing age-related macular degeneration (AMD), but is there evidence to support these uses, and is it safe?

Also, do popular urolithin A supplements on the market really contain what they claim, and how do they compared on quality and cost?

Sign in as a member to get the details in our full answer, which includes information about products including Timeline Mitopure, CodeAge Liposomal Urolithin A, Pure Encapsulations Renual, and Neurogan Health Pro+ Urolithin A, as well as lesser-known brands sold on Amazon.

Also see our separate article about other supplements for building and maintaining muscle.