Best Supplements to Prevent Age-Related Muscle Loss

Latest Update

Ursolic Acid for Slowing Muscle Loss?

Medically reviewed and edited by Tod Cooperman, M.D.

Written by Amy Malec

Updated February 10, 2025 ⓘ

Answer:

After age 30, adults may lose between 3% to 8% muscle mass each decade, and the rate of muscle loss may accelerate after age 60 (Volpi, Curr Opin Clin Nutr Metab Care 2018). Age-related muscle loss (the progressive loss of skeletal muscle mass and strength) may increase the risk of falls and has been associated with increased mortality (Clynes, Calcif Tissue Int 2015).

Some supplements may help to slow the loss of muscle as we age, although some have shown benefit only if combined with resistance exercise, and not all supplements promoted for slowing muscle loss seem to help.

Sign in as a member for details about supplements that may help and some that might not. Supplements discussed include branched-chain amino acids, creatine, fish oil, hydroxymethylbutyrate, protein powders and shakes, urolithin A, ursolic acid, and vitamin D.

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