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Zinc carnosine supplements in wooden spoon in front of oysters


Zinc carnosine, also called polaprezinc, is a complex of the essential mineral zinc and carnosine, which is commonly found in meat and fish and is a water-soluble peptide made of two, linked amino acids (its chemical name is beta-alanyl histidine). Zinc carnosine is promoted for the treatment or prevention of a variety of gastrointestinal disorders including stomach ulcers, Helicobacter pylori infection (which can cause ulcers), aspirin-induced small-bowel injury, taste disorders, and oral mucositis caused by cancer treatment. Although commonly prescribed in Japan for some of these conditions, there is very limited evidence supporting its use for any of these applications.

Sign in for details about the outcomes of scientific and clinical studies done with zinc carnosine, dosage of zinc carnosine, and potential side effects of using zinc carnosine.

For information about other supplements commonly used to eradicate H. pylori and treat stomach ulcers, and to find out if there are any supplements that might worsen symptoms, see our answer to the questions, "Do supplements help treat peptic ulcer disease? Should any be avoided?"

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February 3, 2021

You state that too much zinc can lead to copper deficiency. Is the reverse true? Can too much copper lead to zinc deficiency?
February 3, 2021

That would be unlikely since the issue is competition for absorption and much smaller amounts of copper are typically taken as a supplement than zinc.

Carla 21985
January 28, 2021

Has anyone found Zinc Carnosine to exacerbate rather than improve acid reflux?

June 4, 2021

I am finding this to be true although I have no idea why. I cannot find any evidence online that it could be a side effect other than Amazon reviews, which I take with a grain of salt.

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