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Does Protandim Really Work?

Question:
What is Protandim and does it really work?

Answer:
Protandim (from LifeVantage)  is a supplement containing a patented blend of herbs promoted to reduce oxidative stress. While there are a number of studies on Protandim which have created a lot of press and "marketing buzz," the majority of these are in-vitro and animal studies. There are just two small studies of Protandim supplementation in humans. See the full answer >>


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Ajay119   August 27, 2014
Combining different ingredients might be one approach to claim synergistic or additive effect but at the same time there might be a negative effect due to pharmacokinetic or pharmacodynamic interactions. Therefore it is very important to study the interaction between two ingredients particularly when multiple ingredients are combined. It is very common in pharmaceuticals where two drugs combined may have a negative effect on each others efficacy, absorption and may pose potential side effect. Unfortunately such issue is not addressed for this formulations.
Sometime safety is more important than efficay and i did not see any toxicity or safety data available for this product. Furthermore the antioxidant effect is seen in healthy volunteers but not in diseased conditions.
I think this product needs a reevaluation

Ajay kumar DVM,MS,PhD
Director of Technical Services and Clinical Research
VETSPLUS Inc
Cofounder and chief scientific adviser
Nutraceutra consultants

AJ117   August 27, 2014
You say "may" act as an antioxidant. "May" one conclude from your research that Protandim "may not"? Do your conclusions lead you to believe that Protandim provides benefits for non-humans? I hate to sound so nit picky, but I want to be sure of what you are saying Protandim might be good for at all. Thanking you in advance for clarity.

ConsumerLab.com   September 25, 2014
Hi AJ - Protandim contains antioxidant ingredients, but the available clinical studies to date have not shown any specific health benefit.

This CL Answer initially posted on 8/27/2014. Last updated 8/8/2017.

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