Initially Posted: 12/10/2017 | Last Updated: 09/01/2020
Berberine and goldenseal supplements reviewed by

Alphabetical list of berberine and goldenseal supplements compared in this review


Amazing Formulas Berberine


Bluebonnet Goldenseal Root Extract


Dr. Whitaker Berberine 500 mg


Dr. Whitaker Berberine GlucoGold


Eclectic Institute Goldenseal Root


GNC Herbal Plus Goldenseal Root Extract


Herb Pharm Goldenseal


NutriCology TriBiotics


Only Natural Berberine


Organika Goldenseal

6006_large_6006_large_PipingRock-Berberine-Large-2017.jpg Goldenseal Root


Spring Valley [Walmart] Goldenseal


Thorne Research Berberine-500

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Berberine is a compound found in goldenseal root that may help control blood sugar levels and cholesterol levels, and, potentially may aid in treating certain heart conditions. It is available as a supplement, usually as berberine HCl, or from goldenseal root powders or extracts -- although these typically contain just a fraction of the berberine that's in berberine supplements.
Finding the best quality berberine or goldenseal products was a challenge because many products on the market don't provide the amounts listed on their labels. purchased and tested a range of popular berberine and goldenseal supplements. What did we find? Most goldenseal supplements do not contain their minimum expected amounts of berberine. In fact, one did not contain any detectable berberine despite bearing multiple seals of quality on its label. Even among berberine supplements one was found to provide only 78% of its listed amount of berberine.
Fortunately, we did find a few products that contained what they should and were properly labeled. Among these, we identified those that provide the best value — making them our Top Picks.
You must be a member to get the full test results along with's Top Picks. You'll get results for 13 supplements: 10 selected by and three that passed the same testing in our voluntary Quality Certification Program.

You'll get the following information about berberine and goldenseal supplements in this comprehensive review:
  • Which supplements passed or failed testing - and an easy way to tell which are fake!  
  • Which berberine and goldenseal supplements were Approved for their quality, offer the best value, and are CL's Top Picks
  • What berberine and goldenseal can and cannot do for your health
  • How goldenseal root powder differs from goldenseal root extract
  • The dose of berberine for specific uses
  • What to look for on product labels and how to take berberine and goldenseal supplements
  • Cautions, side effects, and drug interactions with berberine and goldenseal

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