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Woman holding detox supplements in the palm of her hand over various fruits and vegetables on a table

Answer:

There is no convincing clinical evidence that "detox" supplements or over-the-counter "chelation" products help remove toxins from the body or help treat or prevent any medical condition.

In general, the body can eliminate toxins on its own, without additional products. Organs such as the liver, kidneys, gastrointestinal tract, skin and lungs have various pathways by which toxins can be metabolized to safer compounds or excreted from the body (Klein, J Hum Nutr Diet 2015). Consequently, most experts believe that dietary supplements are unlikely to help.

The promotion of supplements as detoxifiers comes mainly from research on animals, such as mice, but research in people is needed to confirm possible benefits (Klein, J Hum Nutr Diet 2015; Sears, J Environ Public Health 2012).

However, getting the recommended amounts of minerals, such as iron, in your diet (including with supplements) may reduce the absorption of toxic metals, such as lead.

Sign in as a member for details about supplement ingredients promoted for helping to eliminate toxins from the body, including selenium, chlorella, modified citrus pectin, zeolite, malic acid, citric acid, and succinic acid, as well as branded products such as Detoxamin by World Health Products and BioToxin Binder by CellCore Biosciences. Also, find out which supplements are promoted for preventing absorption and accumulation of heavy metals in the body.

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4 Comments

Joyce24004
October 20, 2025

I had the "gold test" for heavy metals (a multi-hour urine test) and scored high. My insurance company paid for IV chelation. The body sequesters lead in the bones to get it out of the blood. As you get older and lose bone, the lead comes out. I continue to get IV periodic chelation and will throughout my life. Chelation is possible with EDTA, but only about 5% of it is absorbed when oral. If one takes EDTA, as with IV, it is essential to ensure zinc and other essential minerals are adequate. EDTA preferentially joins with lead, but any extra will join with essential minerals. Rather than "detox" those concerned about heavy metals can find EDTA preparations. Some also contain malic acid, which is reported to chelate aluminum. Apples also contain malic acid, and "An apple a day keeps the doctor away" is a good and tasty idea.

Jeffrey22739
May 08, 2025

There's considerable research on health benefits of modified citrus pectin (too many studies for various health functions to cite.) However, I have not seen any data on pesticide residues in modified citrus pectin. Citrus peel from conventional citrus sources can have notably very high pesticide levels, so analysis of pesticide residues in modified citrus peel would be a great thing to see Consumer Lab analyze.

AnnAnn
June 21, 2024

Wish you would evaluate Detoxamin.

ConsumerLab.com
July 09, 2024

We've added information about Detoxamin and similar products to the following section of our article: https://www.consumerlab.com/answers/detox-supplements-do-they-work-and-are-they-safe/detox-supplements/#chelation

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