Is it safe to take Bioperine (which contains piperine from black pepper)?

Medically reviewed and edited by Tod Cooperman, M.D.

Last Updated: 10/14/2018 | Initially Posted: 08/30/2017

Bioperine Safety -- Turmeric supplements with bioperine

Answer:

Piperine (from black pepper) can enhance the absorption or bioavailability of certain compounds, such as curcumin from turmeric. Bioperine is a branded extract of black pepper which is 95% piperine and is commonly included in curcumin supplements, but is also sold separately. Be aware that piperine can interact with many medications and may also have anti-platelet effects. In addition, it may cause gastrointestinal side-effects and, potentially, bleeding, at somewhat higher-than-suggested doses. See the "Concerns and Cautions" for black pepper extract within the Turmeric/Curcumin Supplements Review.