Initially Posted: 07/18/2019 | Last Updated: 09/12/2020
CoQ10 and Ubiquinol Supplements Reviewed by ConsumerLab.com

Alphabetical list of CoQ10 and ubiquinol supplements compared in this review

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21st Century CoQ-10

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Bluebonnet CoQ10 60 mg Capsules

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BulkSupplements.com Coenzyme Q10

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CVS Health CoQ-10 50 mg

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Doctor's BEST High Absorption CoQ10

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GNC CoQ-10 400 mg

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H2Q

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Healthy Origins Natural Ubiquinol

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Igennus VESIsorb Ubiquinol-QH

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Jarrow Formulas QH-absorb® + PQQ

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Kirkland Signature CoQ10 (Costco)

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Life Extension Super Ubiquinol CoQ10 100 mg

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Member's Mark CoQ-10 (Sam's Club)

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Metagenics NanoCell-Q

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Natural Factors Ubiquinol

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Nature's Bounty Co Q-10 200 mg

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NOW Ubiquinol CoQH-CF

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Nutrilite Heart Health CoQ10

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PipingRock.com CoQ-10 200 mg

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Q10 for Pets - Unflavored Pure CoQ10

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Q10 Vital

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Qgel LiQH

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QGel LiQsorb

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Qunol Mega CoQ10 Ubiquinol

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Spring Valley [Walmart] CoQ10 200 mg - Natural Flavors

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Swanson Q-Gel Mega 200

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USANA Coquinone 30

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Summary

  • What does it do? People often take CoQ10 to offset a decline in natural levels which occurs with the use of statin (cholesterol-lowering) medication. Some take it to feel more energized or for a variety of other purposes. It may also modestly help with elevated cholesterol levels, migraine, and other conditions. The evidence supporting these uses remains preliminary, although it does benefit people with congestive heart failure (see What It Does). After being absorbed into the body, more than 90% of CoQ10 is converted to its active form, known as ubiquinol (CoQH2-10), which is also available as a supplement and appears to have greater bioavailability (i.e., it raises blood levels more) (see What It Is).
  • How much to take? CoQ10 and ubiquinol are typically taken at a dose of 50 to 200 mg per day, although higher doses have been used (see Dosage).
  • What did CL's tests show? In laboratory testing, one product was Not Approved, as it contained nearly twice its listed amount of CoQ10. Cost comparisons showed you could spend as little as 7 cents to over $2 for an equivalent amount of CoQ10, and from 34 cents to over $1 for ubiquinol (See What CL Found).
  • Best choice? Among 26 CL Approved products, CL selected several Top Picks for providing high quality CoQ10 or ubiquinol at very good value.
  • How to take it? Gastrointestinal side-effects may occur but can be minimized by breaking up the dose throughout the day, although it may interfere with sleep if taken before bed. CoQ10 and ubiquinol are best absorbed when taken with or shortly after a fatty meal, although certain forms can be taken without fats (see Absorption and Bioavailability Enhancers).
  • Cautions: At typical doses, CoQ10 and ubiquinol appear to be generally safe, but there are possible interactions with blood thinners and diabetes medications (see Concerns and Cautions).
You must be a member to get the full test results along with ConsumerLab.com's recommendations and quality ratings. You will get results for 18 CoQ10 and ubiquinol supplements selected by ConsumerLab.com and 9 others which passed testing in its voluntary Quality Certification Program. In this comprehensive review, you'll discover:
  • Which CoQ10 and ubiquinol supplements failed testing and which passed
  • CL's Top Picks, representing the best CoQ10 and ubiquinol supplements at lowest cost
  • Which supplements have special ingredients which may increase their absorption (such as polysorbate 80) and/or bioavailability (such as black pepper extract) — and the pros and cons of these formulas
  • CoQ10 and ubiquinol dosing for treating specific conditions
  • How to take CoQ10 and ubiquinol to reduce side-effects and enhance absorption
  • CoQ10 side-effects, drug interactions, and cautions  

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