Share ConsumerLab.com's information with family and friends — or just send to yourself. Simply provide an email address below.
You must provide a valid email address.
Your email address*:
Your name*: Send me a copy
Email Address where it's going*:
*Addresses and name will only be used for sending this message.
Additional message (optional):
Your message has been sent. Thanks for sharing!
ConsumerLab.com Answers
Question: Is P-5-P really better than "regular" vitamin B6?
Answer: Pyridoxal-5-phosphate, sometimes called P-5-P or PLP, is the active form of vitamin B6 (pyridoxine). Most supplements provide the pyridoxine form of B6, although some provide pyridoxal-5-phosphate, or a combination of both. Taken at recommended doses, both forms appear to be relatively safe and have similar bioavailability for most people. Although pyridoxal-5-phosphate is sometimes promoted as more beneficial for people with diabetes, there do not appear to be any studies in people to support this. For more details, see the "What to Consider When Buying" section of the B Vitamin Supplements Review >>
You are not taking into consideration the very real problem of people who have gene mutations which affect their methylation process. The bio-available forms of all B vitamins, especially Folic acid in the form of 5-Methyltetrahydrofolic acid, are a necessity for these people.
Hi Carol - As noted in the section of the B Vitamin Supplement Review linked to in the above answer, P-5-P may be prescribed for people with conditions that prevent the body from converting pyridoxine -- this would include people with certain genetic mutations.
Share your thoughts and comments about this topic in the space below. Please abide by the following rules:
If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study.
If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product.
Please be respectful in your tone.
Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will comments that exceed 2,500 characters.
Comment:
Share your thoughts and comments about this topic in the space below. Please abide by the following rules:
If you make a statement of fact, such as whether a type of treatment does or does not work, state your basis -- such as personal experience or a published study.
If you make a positive or negative comment about a product, note whether or not you have a financial interest in the product or in a competing product.
Please be respectful in your tone.
Please do not submit any type of HTML markup or scripting as it will not be accepted, nor will comments that exceed 2,500 characters.
Comment:
You can modify your comment below. Please be aware the comment will have to approve the changes before they will be shown:
Comment:
Your edit has been submitted and is being reviewed by ConsumerLab.com prior to publication.
This CL Answer initially posted on 10/21/2015.
Last updated 8/2/2017.
ConsumerLab.com members may submit questions to CLAnswers@ConsumerLab.com. We read all questions and try to answer those of popular interest.
