- Do B vitamins help? While most people are not deficient in B vitamins (since these vitamins can be easily obtained from foods), older people and those taking medication to reduce stomach acid may be low in B-12 and taking it can help slow age-related decline in memory. Pregnant women should be sure to get folate from a supplement to help avoid birth defects, and people with genetic mutations affecting the MTHFR enzyme may benefit from a form of folate known as methylfolate. High-dose niacin can help lower high cholesterol levels. Although the evidence is preliminary, a high dose of biotin may help strengthen nails. More information about what each of the B vitamins can and cannot do is found in the Background section and in the ConsumerTips sections for each of the B vitamins.
- How much of each B vitamin to take: This depends on your nutritional needs but, generally, B vitamin supplements are formulated to provide much more than you need and this can be a problem for the three B vitamins that can cause toxicity — niacin, folate and B-6. Too much B-12 may also cause problems, including acne. Furthermore, it is now acknowledged that you need less of many B vitamins than believed in the past, but % Daily Value figures on labels don't have to reflect this until the beginning of 2021. In the results table, we show you how products stack up against the latest recommendations (see the numbers in green), as well as which exceed the tolerable limits for niacin, folate, and B-6.
- Which B vitamin supplement is best? For each B vitamin or B complex, we identify CL's Top Picks. These "picks" were found in testing to be accurately labeled for B vitamins, meet other quality criteria, and, represent excellent value for your money. However, five products (mostly B complexes) failed our tests for providing far less or more ingredient than listed. One of these is a popular B complex that, due to an overage, exceeds the tolerable upper intake level for folate from its synthetic form, folic acid. These five products are listed as "NOT APPROVED" in the results table.
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B Vitamin Supplements Review (B Complexes, B6, B12, Biotin, Folate, Niacin, Riboflavin & More)
Be Careful Choosing B Vitamins. 18% of B Vitamins Fail Our Review. See Which Are Best.
Medically reviewed and edited by Tod Cooperman, M.D.
B vitamin supplements compared in this review :
21st Century B-1 100 mg
Amazon Elements Berry B12
Bio-Tech B2-400
Bluebonnet Vitamin B6 50 mg
BulkSupplements.com Flush-Free Niacin
Carlson Methyl Folate
Doctor's Best Benfotiamine 300
Doctor's Best Fully Active Folate 400
Douglas Laboratories Riboflavin
Elysium Basis Cellular Health & Optimization
Eniva B-Complex
Finest Nutrition [Walgreens] Folic Acid
Garden of Life mykind Organics B-Complex Once Daily
GNC B-Complex Big 100
GNC Methyl B-12
Jarrow Formulas B-Right
Jarrow Formulas Pantothenic Acid B5
Kirkland Signature [Costco] Super B-Complex
Mason Natural B12 50 mcg
Nature Made Super B Energy Complex
Nature's Bounty Biotin 10,000 mcg
Nature's Way Pantothenic Acid
New Chapter Perfect Hair, Skin & Nails
NOW Niacinamide 500 mg
NutraBlast Hair Skin & Nails - Strawberry
NutriCology Pantethine
Nutrilite Vitamin B Dual-Action
Organika Vitamin B Complex
PipingRock.com Vitamin B-6 100 mg
Pure Encapsulations B12 Liquid
Puritan's Pride Ultra Mega Biotin 10,000 mcg
Seeking Health Active B12 with L-5-MTHF
Slo Niacin
Solgar Folate 1,333 mcg DFE
Spring Valley [Walmart] Biotin 10,000 mcg
Sugarbearhair Hair Vitamins
Vitafusion B12 - Natural Raspberry Flavor
Make sure the B-complex or B vitamin supplement you take passed our test and is right for you!
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Summary
Which B vitamin supplements failed testing and which passed
Cost comparisons and quality ratings of B vitamin supplements
Information on what B vitamin supplements can and cannot do for you -- some may reduce memory decline!
Important differences among forms of B vitamins, such as those of niacin (nicotinic acid, niacinamide, and inositol hexanicotinate), folate (natural folate, folic acid, and L-5-methyltetrahydrofolate), and B-12 (methylcobalamin and cyanocobalamin), as well as how oral B-12 compares to B-12 injections.
Use and dosage information for thiamin, niacin, vitamin B-6, B-12, biotin, folate (folic acid), and pantothenic acid.
How amounts of B vitamins in supplements compare to the amounts you actually need - the results may surprise you!
What you need to know about new intake guidelines — and why you shouldn't rely on Daily Values (DVs) listed on labels
Side effects and potential drug interactions with B vitamins
Safety concerns with B vitamins, and how to use them safely
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Latest Clinical Research Updates for B Vitamin Supplements
Oral Symptoms of B-12 Deficiency
12/24/2021
High-dose Folate for Depression
11/15/2021
Niagen for Energy?
10/09/2021
Biotin Interference With COVID Tests
8/28/2021
Danger With Too Much B-6
8/14/2021
Best Form of B-12 for Vegans?
8/10/2021
Hidden Forms of B-12 Deficiency
7/13/2021
Niacin for Parkinson's?
7/10/2021
Also see our answer to the question: Do supplements help with Parkinson's disease treatment or prevention?
Folic Acid for Hot Flashes?
5/18/2021
Folic Acid and Colorectal Cancer
3/23/2021
Folic Acid for Cognitive Function?
2/28/2021
Energy Drinks and Blood Pressure
2/10/2021
Thiamin Deficiency from Bowel Disease
2/03/2021
B12 for Diabetic Neuropathy?
1/31/2021
Nicotinamide Riboside to Slow Aging and Reverse NAD+ Decline?
1/13/2021
Magnesium, Niacin and Blood Pressure
1/10/2021
Two studies this week showed the risk of high blood pressure to be lowest among people with adequate, but not excessive, dietary intakes of magnesium and niacin.
Also, see which foods are good sources of magnesium and, separately, good sources of niacin.
B-12 for Eczema?
12/23/2020
B-12 for Singers
11/18/2020
Biotin for MS?
11/11/2020
Muscle Cramps from Lack of Vitamin
11/04/2020
High-Dose Vitamin B-6 & Cancer
10/20/2020
Folate & Memory
9/01/2020
B-12 Supplements vs. Injections
8/25/2020
B Vitamins and Fracture Risk
8/06/2020
High Blood Pressure Risk With Too Much Folic Acid During Pregnancy
5/15/2020
Also see our Top Pick among prenatal vitamins, which provides adequate (but not too much) folic acid, in our Multivitamin and Multiminerals Supplements Review.
Early Sign of Thiamin Deficiency
4/28/2020
Biotin May Skew Many Blood Tests
2/29/2020
Cognitive Impairment From B12 Deficiency
2/25/2020
Vitamin B12 and Risk of Death
2/11/2020
B12 & the Vegetarian
12/14/2019
B Vitamins for Cognition
11/29/2019
Platelet Concern With High-dose Niacin
11/11/2019
Eye Risk With High-Dose Niacin
11/01/2019
Vitamin B12 & Sleepiness
9/21/2019
Folic Acid and Colon Cancer
8/13/2019
Is Niagen Safe?
7/20/2019
Is Methylfolate the Best Form of Folate?
7/16/2019
NAD+ and Cancer?
6/19/2019
Vitamin B12 & Depression
5/28/2019
Hip Fracture Risk with B6
5/18/2019
Misdiagnosed B12 Deficiency
5/18/2019
Energy Drinks & Aggression
2/16/2019
B12 Tablet vs. Injection
1/15/2019
B Vitamins & Breast Cancer
1/08/2019
Liver Toxicity With Niacin
11/20/2018
B Vitamin Cancer Risk?
10/24/2018
Can a B Vitamin Lower High Blood Pressure?
10/09/2018
Niagen for Blood Sugar Control?
7/10/2018
Methylfolate vs. Folic Acid
6/12/2018
Hair & Nail Supplements Can Skew Lab Tests
5/22/2018
Too Much Vitamin B6
5/15/2018
What Niagen Does
4/03/2018
B12 Dosage
3/07/2018
Folic Acid, Multis & Autism Risk
2/25/2018
B12 for Cognition
1/13/2018
Folic Acid & Risk of Autism
12/26/2017
Folic Acid for Cognition
12/23/2017
Danger from Too Much Vitamin B6
12/14/2017
CL has long warned that energy drinks and shots often contain large amounts of B6 and other B vitamins.
Biotin Interference With Vitamin D Test
12/05/2017
Growing Concern with Biotin Causing False Lab Results
11/28/2017
Signs of B12 Deficiency
11/26/2017
B Vitamins for Memory
11/04/2017
Best form of B12?
10/29/2017
Niacinamide for Alzheimer's Disease?
9/19/2017
Lower Cognitive Function in Kids Linked to High Prenatal Folic Acid
9/06/2017
High-Dose B Vitamins & Lung Cancer Risk
8/29/2017
High-Dose B Vitamins & Cataract Risk
8/26/2017
How Vitamin B6 May Backfire
7/26/2017
Warning: Biotin Can Affect Thyroid Tests
6/20/2017
B12 Can Cause Acne
6/20/2017
Hip Fracture Risk With Too Much B-6
6/10/2017
POTS and Thiamin
5/24/2017
Niacin & Skin Cancer
4/19/2017
Cognitive Decline With Too Little B6
2/03/2017
Side-Effect With B-12
1/20/2017
Potential Risk with High B-12
1/10/2017
High-Dose Vitamin D Reduces Respiratory Infections, But With a Risk
1/10/2017
Too Much Folate & Nerve Damage
10/22/2016
Niagen Form of Niacin May Cause Flushing
10/11/2016
Getting Too Much Folic Acid
9/16/2016
Biotin Caution
8/20/2016
Folic Acid Supplementation Mitigates Alzheimer's
7/05/2016
B Vitamins & Autism Risk
6/12/2016
Omega-3's May Be Important in Preventing Cognitive Decline
1/20/2016
Niacin Helps Prevent Skin Cancers
10/24/2015
How Vitamin B-12 Causes Acne
6/27/2015
Niacin Reduces Skin Cancer
5/16/2015
Folic Acid Reduces Risk of Stroke
3/15/2015
Keep Energy Drinks Away from Kids
11/17/2014
Do B Vitamins Boost Memory?
11/16/2014
Energy Drinks: Athletic Performance & Side Effects
10/08/2014
High-Dose Niacin with Statins Not Worth It
7/19/2014
B-12 Deficiency and Acid Inhibitors
12/14/2013
For more information, see ConsumerLab's answer to the question, I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?.
B Vitamin Supplements for Stroke?
9/21/2013
Alzheimer's Changes Slowed with B Vitamins
5/27/2013
Concern Over Carnitine Causing Cardiovascular Disease
4/14/2013
For more details, see the updated reviews of B Vitamin Supplements & Energy Drinks and Protein Powders, as some of these products contain L-carnitine. The Acetyl-L-Carnitine Supplements review has also been updated because acetyl-L-carnitine is chemically similar to L-carnitine, suggesting a potential concern.
Concern Over Niacin
3/17/2013
Autism and Folic Acid Supplements
2/17/2013
Higher Vitamin Level May Slow Cognitive Decline
12/16/2012
Caution with Energy Drinks
11/18/2012
B Vitamin May Lower Blood Pressure
5/20/2012
B-12 and Folic Acid for Memory
1/08/2012
No Benefit of Niacin with Statins
11/20/2011
B Vitamins May Help Memory
10/30/2011
Niacin Concern Stops Cardiovascular Study
5/31/2011
Does folic acid affect the risk of colon cancer?
5/09/2011
Related CL Answers (74)
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