- / CL Answers
- / I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?
Our Members Asked:
I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?
Reviewed and edited by Tod Cooperman, M.D.
Answer:Fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil) and other selective serotonin-reuptake inhibitor (SSRI) drugs can be affected by taking supplements and can affect your ability to absorb certain vitamins and minerals. Certain herbal supplements, such as St. John's wort and Garcinia cambogia (HCA), may increase the risk of serotonin syndrome associated with SSRIs. Other supplements, like 5-HTP, and SAMe, may also increase this risk.
On the other hand, folic acid, a B vitamin, may be beneficial for some people taking an SSRI.
Join today to unlock all member benefits including full access to all CL Answers and over 1,300 reviews.Join Now
Already a member? Sign In Here.
Join now at www.consumerlab.com/join/
Related CL Answers (14)
Does Procera AVH really improve memory and mood?
Procera AVH information, including evidence from clinical studies on memory, cognition, mood, safety, and a lawsuit.
I take St. John's wort for depression. Your report notes that it can interact with other medications. Would taking it several hours apart from other meds avoid this interaction?
St. John's wort (Hypericum perforatum) can interact with other medications, but can this be avoided by spacing out the dosages?
I've heard that having low B-12 or B-6 can cause depression. Is that true?
Find out if vitamin B12 or B6 deficiency can cause depression and how they can affect antidepressants.
I'm taking Lumiday, a supplement to improve mood. It seems to help me but is it safe?
Lumiday info including side effects, drug interactions and reviews. Lumiday is a supplement marketed to improve mood.
Can melatonin supplements cause depression or make depression worse?
Find out if melatonin supplements can cause depression or make depression worse. ConsumerLab.com's answer explains.
What are the symptoms of vitamin D deficiency?
Learn about the symptoms of vitamin D deficiency, such as soft or weak bones, bone, joint and muscle pain, depression, insomnia, hair loss and others, and find out how much vitamin D you need. ConsumerLab.com's answer explains.
Is Rhodiola rosea effective for depression and does it have other uses? Will ConsumerLab.com be testing these supplements?
Learn more about Rhodiola rosea, it's impact on depression and anxiety, including evidence from clinical studies and safety.
What are the best supplements for depression and anxiety?
Best natural supplements for depression and anxiety, including the evidence for fish oil, vitamin D, probiotics, and herbal supplements for depression such as curcumin (from turmeric) and saffron.
Does magnesium help with depression?
Find out if having low magnesium levels increases the risk of depression and if supplements such as magnesium citrate, magnesium chloride, can help for depression. Also, find out how to make sure you are getting adequate magnesium. ConsumerLab.com's answer explains.
Are light boxes effective for preventing and treating seasonal affective disorder (SAD), also known as "winter depression"? Which light boxes are best?
Learn about the benefits and safety of light boxes (including who is most likely to benefit), how to use these devices, which commercially available products appear to meet the technical requirements, and who should not use light boxes.
Are there any supplements I should avoid when taking acetaminophen (Tylenol)?
Find out if there are any supplements that should be avoided when taking acetaminophen (Tylenol).
I've read about several different forms of SAMe. Is one form better than another?
Learn about the various types of SAMe (S-adenosyl-L-methionine) supplements, along with their benefits for hormones & cell membrane health.
What are the most common, potentially dangerous interactions between supplements and drugs?
Info on the most common, potentially dangerous, interactions between drugs & supplements, including Lisinopril interactions and others.
Related Reviews (4)
Recent CL Answers
- Are supplements such as Thyroid Care Plus helpful for hypothyroidism? Can supplements worsen thyroid function? And what is nascent iodine?
- Which supplements can help treat anemia? Can any supplements cause a low red blood cell count?
- Can fluoride in toothpaste, mouth rinses or drinking water cause attention-deficit/hyperactivity disorder (ADHD) in children?