Our Members Asked:
Can melatonin supplements cause depression or make depression worse?
Only when taken at extremely high doses has melatonin has been reported to worsen symptoms of depression or to cause depression. For details, as well as information about other potential side effects of melatonin, see the Concerns and Cautions section of the Melatonin Supplements Review >>
Related CL Answers (12)
Are light boxes effective for preventing and treating seasonal affective disorder (SAD), also known as "winter depression," or circadian rhythm disorders such as jet lag? Which light boxes are best?
Learn about the benefits and safety of light boxes (including who is most likely to benefit), how to use these devices, which commercially available products appear to meet the technical requirements, and who should not use light boxes.
Does magnesium help with depression?
Find out if having low magnesium levels increases the risk of depression and if supplements such as magnesium citrate, magnesium chloride, can help for depression. Also, find out how to make sure you are getting adequate magnesium. ConsumerLab.com's answer explains.
What are the side effects of melatonin supplements?
Melatonin side effects - are there any? Read about drowsiness, dizziness, headache, nausea, mood & behavior, the risk of fractures and others. ConsumerLab.com's answer explains.
Can melatonin help with stomach pain?
Find out if melatonin supplements can help with stomach pain, ulcers, reflux and dyspepsia, or if it can cause stomach upset.
I take melatonin to help me fall asleep. Are there any drugs that interact with melatonin that I should be aware of ?
Melatonin interactions with drugs, including blood pressure medications, Xanax, Ambien, antidepressants, caffeine and more.
I've heard that melatonin may increase the risk of broken bones. I take melatonin regularly. Should I be concerned?
Learn more about how melatonin may affect bone density and risk of fracture.
Is it safe to take melatonin when taking prescription sedatives or sleep aids like lorazepam (Ativan) or zolpidem (Ambien)?
Safety information on taking melatonin while using prescription sedatives or sleep aids like lorazepam (Ativan) or zolpidem (Ambien).
What are the best supplements for depression and anxiety?
Best natural supplements for depression and anxiety, including the evidence for fish oil, vitamin D, probiotics, and herbal supplements for depression such as curcumin (from turmeric) and saffron.
What is the best way to take melatonin to get a good night's sleep?
Learn more about the best way to take melatonin for better sleep. When to take it, how to take it, and general melatonin information.
I'm taking Lumiday, a supplement to improve mood. It seems to help me but is it safe?
Lumiday info including side effects, drug interactions and reviews. Lumiday is a supplement marketed to improve mood.
I've read about several different forms of SAMe. Is one form better than another?
Learn about the various types of SAMe (S-adenosyl-L-methionine) supplements, along with their benefits for hormones & cell membrane health.
I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?
Learn about Prozac (fluoxetine) drug interactions along with other supplements and SSRIs.
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