Our Members Asked:
What are the best supplements for depression and anxiety?
A wide variety of natural supplements have shown some benefit in reducing depression and/or anxiety. Certain vitamin and mineral deficiencies can also cause depression.
Sign in to learn more how the following relate to depression and anxiety: Fish oil, CBD oil, probiotics, curcumin (from turmeric), saffron, 5-HTP, St. John's wort, SAMe, DHEA, Rhodiola rosea, folic acid, L-theanine, ashwagandha, N-acetyl cysteine (NAC), melatonin, valerian, kava, palmitoylethanolamide (PEA), apple cider vinegar, B vitamins, vitamin D, magnesium, and glucosamine.
Latest Research Updates (Clinical Updates)
Kava Interactions With Medications
A CL Member noted that kava (which some people take to treat anxiety) may interact with medications prescribed to treat anxiety. We have added information about this to our CL Answer about kava interactions with medications.
Also see our article about supplements to avoid when taking Valium or Xanax.
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What are the health benefits of holy basil extract?
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Does magnesium help with depression?
Find out if having low magnesium levels increases the risk of depression and if supplements such as magnesium citrate, magnesium chloride, can help for depression. Also, find out how to make sure you are getting adequate magnesium. ConsumerLab.com's answer explains.
Rhodiola and ashwagandha are both promoted to help with stress and anxiety. Is it safe to take them at the same time?
Find out if it is safe to take ashwagandha and rhodiola together. Both herbs are promoted to help with stress and anxiety, but may also lower blood pressure and have other side effects. ConsumerLab.com's answer explains.
Can melatonin supplements cause depression or make depression worse?
Find out if melatonin supplements can cause depression or make depression worse. ConsumerLab.com's answer explains.
Are lithium orotate supplements as effective and safe as prescription lithium for bipolar disease and depression?
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I've heard that having low B-12 or B-6 can cause depression. Is that true?
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I take St. John's wort for depression. Your report notes that it can interact with other medications. Would taking it several hours apart from other meds avoid this interaction?
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A blood test showed my vitamin D level is low. How do I know how much vitamin D to take?
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Are there any supplements I should avoid when taking Valium or Xanax?
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Is Rhodiola rosea effective for depression and does it have other uses? Will ConsumerLab.com be testing these supplements?
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I'm taking Lumiday, a supplement to improve mood. It seems to help me but is it safe?
Lumiday info including side effects, drug interactions and reviews. Lumiday is a supplement marketed to improve mood.
I've read about several different forms of SAMe. Is one form better than another?
Learn about the various types of SAMe (S-adenosyl-L-methionine) supplements, along with their benefits for hormones & cell membrane health.
I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?
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