Our Members Asked:
Are there any supplements I should avoid when taking acetaminophen (Tylenol)?
Acetaminophen (Tylenol, paracetamol) is the most common drug ingredient in the U.S. and is found in more than 600 combination formulas, including Alka-Seltzer Plus Cold formula and the drug Percocet. Although few supplement interactions with acetaminophen have been reported in people, research suggests certain vitamins and herbs may affect how acetaminophen is metabolized in the body — increasing its potential for adverse effects or decreasing its effectiveness. In addition, if you are taking high doses of acetaminophen (which can cause liver damage), it may be best to avoid supplements with the potential to damage the liver. Certain foods can also interact with acetaminophen. There has been some concern over the risk of bleeding when using herbal supplements along with acetaminophen, although recent evidence argues against this. Be aware that effervescent formulations of acetaminophen may contain significant amounts of sodium.
For details, including the specific supplements of concern, see the full answer >>
Related Reviews (10)
Related CL Answers (10)
Can CBD cause a drop in blood pressure?
Find out if CBD (cannabidiol) can lower blood pressure or affect heart rate, plus information about other CBD side effects, drug interactions and safety concerns. ConsumerLab.com's answer explains.
Can hemp oil or CBD (cannabidiol) supplements cause me to fail a marijuana drug test?
Find out if you can fail a drug test dues to hemp oil or CBD (cannabidiol) supplements. Plus info on how much THC is in hemp oil and CBD products. ConsumerLab.com's answer explains.
Can taking N-acetylcysteine (NAC) supplements reduce my risk of liver damage from acetaminophen?
Information on taking NAC supplements (N-acetylcysteine) to reduce the risk of liver damage from acetaminophen.
What are the most common, potentially dangerous interactions between supplements and drugs?
Info on the most common, potentially dangerous, interactions between drugs & supplements, including Lisinopril interactions and others.
I take lisinopril (Zestril), an ACE inhibitor drug to lower blood pressure. Are there supplements I should avoid, or be taking, due to this drug?
When taking ACE inhibitors, find out which supplements should be avoided. Interaction info on Lisinopril or another ACE inhibitors.
I take levothyroxine (Synthroid), a thyroid hormone to treat hypothyroidism. Are there supplements or foods I should avoid, or be taking, due to this drug?
Is taking certain supplements and hypothyroidism medications bad? Learn which supplements can interact with thyroid hormone medications like levothyroxine (Synthroid), thyroid hormone levels, and laboratory tests.
I take insulin (Humalog) for diabetes. Are there supplements that could affect my blood sugar levels and how much insulin I need to take?
Learn more about the interactions between certain supplements and insulin (sold as Humalog, Humulin, Iletin, Lantus, Levemir, Novolin, Novolog, Velosulin, etc.).
I take fluoxetine (Prozac), a SSRI drug to treat depression. Are there supplements I should avoid, or be taking, due to this drug?
Learn about Prozac (fluoxetine) drug interactions along with other supplements and SSRIs.
When taking a statin drug like Lipitor or Crestor, are there supplements I should avoid or take?
Learn about the interactions between certain supplements and atorvastatin (Lipitor), rosuvastatin (Crestor), and other cholesterol-lowering statins.
I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?
Supplement interactions with proton pump inhibitor (PPI) drugs like omeprazole (Prilosec) and Nexium.
Join over 90,000 Members
Find the best products with instant access to our latest tests & reviews of over 1,400 health products.
Save money by finding high-quality products at lower cost.
Stay safe with the latest clinical findings & warnings.
See answers from our experts.
Stay informed with our e-newsletter.
Ratings of ConsumerLab
The "Updated" date indicates when new information was most recently added to this article. In the full article, the newest information is highlighted in yellow.