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Lysine and Vitamin B12 for Canker Sores
Question: Can lysine or vitamin B-12 help prevent or reduce canker sores?
Answer: There is some evidence that the amino acid L-lysine may help to prevent canker sores (also known as aphthous stomatitis) and reduce healing time. (Lysine may also help to reduce the occurrence and severity of cold sores (herpes simplex labialis), although the evidence is mixed). For details, including dosage and our tests of products, see the Lysine Supplements Review >>
In people with recurrent canker sores, a daily dose of vitamin B-12 was found to reduce the number and duration of outbreaks, as well as decrease pain, according to one study. More details, including dosage, and our tests of B-12 supplements, can be found in the B Vitamins Supplements Review >>
For information about other proposed treatments, see the Encyclopedia article about Canker Sores.