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Supplements for Raynaud's Phenomenon -- woman standing outside in snow, with cold, red hands


There is some evidence that certain supplements may be helpful for Raynaud's phenomenon (abnormal sensitivity of hands and feet to cold). For example, Ginkgo biloba, inositol hexanicotinate (a form of the B vitamin niacin), and ginseng have shown some benefit (click on the links for more details). One small study suggests a possible benefit with fish oil supplementation, but more research is needed.

Combined with standard management (avoiding cold, wearing gloves, etc.) Pycnogenol, a branded pine bark extract supplement, was shown to reduce pain and discoloration, and increase finger temperature compared to standard management alone in a preliminary study.

Several other types of supplements have been tried without success. For example, beetroot juice was found to provide little benefit to people with Raynaud's in a small study of older adults. In comparison to the reaction to cold before being given beetroot juice, the reaction to cold after taking beetroot juice daily for two weeks (2.4 oz for 13 days and 4.7 oz. on the fourteenth day), showed modestly increased blood flow to the thumb but not to all fingers (averaged) and improved vasodilation in the forearm. However, it did not reduce pain or increase skin temperature and it had no effect on the feet (Shepherd, J Appl Physiol 2019). (See the CL Answers about beetroot juice for lowering blood pressure and improving exercise performance).

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September 7, 2016

What about L-Arginine?
September 8, 2016

Hi Mike - L-arginine has been tried in treating Raynaud's but results to-date have been mixed. This is discussed in more detail in our L-arginine Supplements Review:

September 6, 2016

B6 has helped me regulate temperature and reduce my temperature sensitivity to cold.

September 5, 2016

I have had Raynaud's phenomena for years. It was really accelerating and affecting me in summer months and moved to my face. Doctor's talked about pills to help with vascular issues but I wanted to get to the root cause. i went off of all gluten and corn and my Raynaud's is 95% better. I only have sporadic issues and it is only the tips of my fingers. I went off of gluten and corn for gut issues and my Raynaud's became controlled.

September 6, 2016

Yes! so much of what goes on in the body arises from the gut...

September 4, 2016

I suffer from what seems to like Reynaud's, I have Multiple Sclerosis, Raynaud's or a Reynauds like effect seems to be fairly common among some with MS. Do any of the supplements appear helpful with MS patients?

September 4, 2016

I have had great results with a product called METANX that is a mixture of methylated B6, methylated B12 and methylated Folate. I am not sure which of these ingredients is actually responsible for the improvement since this product contains all 3. All I know is that it has helped me significantly. I passed this along to several others I know that have Raynauds phenomenon, and they benefited as well. I have no financial interest in Metanx nor in any competing product.

Teresa 18541
October 16, 2019

Angela 11236
Thank you so much for posting this information. I am excited to give this a try since my Raynauds is so painful.

September 4, 2016

Magnesium needs to be studied as a means of improving vascular dysregulation. It is involved in normal tension glaucoma, which results from this condition. Supplements may offer the equivalent of about 400 mg per day, which is a very reasonable amount.

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