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NAD Boosters (NAD+/NADH, Nicotinamide Riboside, and NMN)

NAD Boosters (NAD+/NADH, Nicotinamide Ribose, and NMN)

Several supplements can boost levels of NAD in the body, but does it matter and how do these products compare? Find out in this review in which ConsumerLab purchased and tested the quality of popular NAD+, NADH, nicotinamide riboside, and NMN supplements and evaluated the research behind them.

NAD Boosters (NAD+/NADH, Nicotinamide Riboside, and NMN) Review

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CL Answer

Does nicotinamide riboside (as in Niagen and Basis) really have anti-aging or other health benefits?

Niagen (Nicotinamide riboside) information, including if it actually provides anti-aging or other health benefits. ConsumerLab explores this question.

CL Answer

Is it okay to take vitamin D3 and fish oil together?

Find out if taking vitamin D and fish oil is okay, how it effects absorption, and the best way to take vitamin D to improve absorption. ConsumerLab.com's answer explains.

hand holding vitamin D and fish oil capsules

Clinical Update

2/15/2022

NMN for Better Sleep?

Can nicotinamide mononucleotide (NMN) improve sleep and reduce daytime drowsiness? See what a new study found in the What It Does section of our NAD Booster Supplements Review. Also see our Top Picks among products, including NMN, NAD+/NADH, and nicotinamide riboside.

See our answer to the question: Which supplements can help me sleep and which cause insomnia?

Clinical Update

12/10/2021

64% of NMN Supplements Fail Tests

Fourteen of the 22 most popular NMN supplements (which can boost NAD+ levels) on Amazon were recently discovered to contain no detectable NMN. See the results in the Update to our NAD Boosters Review, which includes CL's tests of additional NMN, NADH, and nicotinamide riboside supplements, as well as our Top Picks.

Clinical Update

12/12/2023

Nicotinamide Riboside Side Effects

What are the common side effects of nicotinamide riboside (found in Tru Niagen), and is it safe? Find out what a recent study showed in the Concerns and Cautions section of our NAD Booster Supplements Review. Also see our Top Picks for nicotinamide riboside and other NAD boosters.

Clinical Update

11/15/2022

NAD Booster & Cancer Risk

The NAD booster, nicotinamide riboside, increased the spread of certain aggressive cancers in a recent laboratory study, adding to existing concerns. Get the details in the Concerns and Cautions section of our NAD Booster Supplements Review.

Also, see our CL Answer about vitamins and cancer risk.

Clinical Update

2/03/2023

Niacin & Cancer?

The NAD booster, nicotinamide riboside, might promote growth of existing cancers. Is there similar risk with niacin and niacinamide (nicotinamide)? Find out what evidence suggests in the Concerns and Cautions section of our NAD Booster Supplements Review.

Also, see our Top Pick among niacin supplements in our B Vitamin Supplements Review.

Clinical Update

5/13/2022

New Nicotinamide Riboside Top Pick

We recently tested and Approved a nicotinamide riboside supplement that provides the most-studied form of nicotinamide riboside and is our new Top Pick for nicotinamide riboside in our NAD Booster Review.

Clinical Update

2/13/2024

Supplement for Cognition?

Does taking nicotinamide riboside improve cognitive or physical function among older people with mild cognitive impairment? See what a recent study showed in the Nicotinamide riboside section of our NAD Booster Supplements Review. Also see our Top Pick for nicotinamide riboside.

Also see our article about supplements for memory and cognition.

Clinical Update

2/28/2023

Nicotinamide Riboside for Alzheimer's?

A preliminary clinical study suggested that taking nicotinamide riboside reduced blood markers of Alzheimer’s disease. For details, see the What It Does section of our NAD Boosters Review, which includes our Top Pick among nicotinamide riboside supplements.

Also see: Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?

Clinical Update

1/13/2021

Nicotinamide Riboside to Slow Aging and Reverse NAD+ Decline?

Nicotinamide riboside, a form of niacin, has been promoted to slow aging, partially based on the belief that it raises NAD+ levels that fall with age. A new study raises doubts about this. Get the details in the Niacin section of our B Vitamin Supplement Review. Also, learn about a concern with taking too much nicotinamide riboside.

News Release

November 05, 2021

NAD Boosters for Energy and Memory? ConsumerLab Reviews NAD+, NAHD and NMN Supplements

White Plains, New York, November 5, 2021 — Most cells in the body use NAD (nicotinamide adenine dinucleotide) in the process of energy production, and compounds that boost blood levels of NAD are often sold in supplements marketed for a wide range of benefits, from increasing energy and ...

Clinical Update

6/19/2019

NAD+ and Cancer?

Supplements that raise NAD+ levels in the body have been promoted for anti-aging effects. But there is a theoretical risk that they could stimulate cancerous cells, and a CL member reported this week that a supplement containing such an ingredient, nicotinamide riboside, appeared to increase his PSA level. Learn more in the Niacin section of the B Vitamin Supplements Review.

Clinical Update

11/15/2022

NMN Can No Longer Be Sold as a Supplement

The FDA recently took the position that NMN, an NAD booster, cannot be sold as a dietary supplement. For details, see the NAD Boosters Review.

Clinical Update

7/20/2019

Is Niagen Safe?

Niagen (nicotinamide riboside) was recently studied for its safety and ability to raise NAD+ in the body. See the results and learn more about this form of niacin (which is also in the product Basis) in the Niacin section of the B Vitamin Supplements Review. Also see our Top Picks for niacin and other B vitamin supplements.

Recalls & Warnings

December 01, 2020

Niagen Cannot Be Promoted to Prevent or Treat COVID-19, Warns FDA

On November 17, 2020, the FDA issued warning letters to the sellers of Niagen and Nadovim, supplements that contain different forms of niacin, for selling products with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

May 09, 2020

FDA Warns Sellers of Essential Oils, CBD, Vitamins, and More Promoted to Treat Coronavirus

Between May 7 and May 8, 2020, the FDA issued warning letters to seven companies for selling products such as essential oils, CBD, hand sanitizers, and vitamins with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

December 06, 2013

Weight Loss Supplement Claims Challenged

On November 27, 2013, the National Advertising Division (NAD) recommended HealthyLife Sciences, LLC, modify or discontinue the use of certain claims made about the company's weight loss supplement Healthe Trim.

Recalls & Warnings

April 12, 2013

Zicam Advised Against Using Cold Prevention Claim In Advertising

On April 5, 2013, it was reported that the National Advertising Division (NAD) recommended that Matrixx Initiatives, maker of Zicam cold products, stop making claims in its advertising that the product can prevent colds.

Recalls & Warnings

September 13, 2014

Marketer Banned From Selling Weight Loss Products

In order to settle FTC charges of deceptive weight loss claims, John Matthew Dwyer III, the co-founder of HealthyLife Sciences, LLC, has agreed to no longer manufacture or market weight loss supplements.