ConsumerLab.com uses JavaScript to provide the best possible experience for our content, but your browser has it disabled. Learn how to enable it here.

NAD Boosters (NAD+/NADH, Nicotinamide Riboside, and NMN)

NAD Boosters (NAD+/NADH, Nicotinamide Ribose, and NMN)

Several supplements can boost levels of NAD in the body, but does it matter and how do these products compare? Find out in this review in which ConsumerLab purchased and tested the quality of popular NAD+, NADH, nicotinamide riboside, and NMN supplements and evaluated the research behind them.

NAD Boosters (NAD+/NADH, Nicotinamide Riboside, and NMN) Review

Search term may appear only in full report available to members. Join now for full access.

Clinical Update

3/26/2024

NMN Off Walmart, iHerb

Walmart and iHerb have joined Amazon in no longer selling NMN (nicotinamide mononucleotide) supplements. To find out why, see the NAD Boosters Review, which includes our tests of NMN, NADH, and nicotinamide riboside products and our Top Picks among them.

Read more about NMN Off Walmart, iHerb

Clinical Update

1/02/2025

Is NMN Still Sold?

NMN (nicotinamide mononucleotide) supplements are no longer sold by Amazon and Walmart. Find out why and where NMN is still sold in our NAD Booster Supplements Review, which includes our Top Picks among products.

Read more about Is NMN Still Sold?

Clinical Update

2/15/2022

NMN for Better Sleep?

Can nicotinamide mononucleotide (NMN) improve sleep and reduce daytime drowsiness? See what a new study found in the What It Does section of our NAD Booster Supplements Review. Also see our Top Picks among products, including NMN, NAD+/NADH, and nicotinamide riboside.

See our answer to the question: Which supplements can help me sleep and which cause insomnia?

Read more about NMN for Better Sleep?

Clinical Update

9/19/2025

NMN for Anti-Aging?

Does nicotinamide mononucleotide (NMN) improve muscle or brain function in older men? See what research suggests – and our take on it -- in our NAD Booster Supplements Review, which includes our Top Picks for NMN, as well as NAD/NADH and nicotinamide riboside.

Read more about NMN for Anti-Aging?

Clinical Update

6/04/2026

NAD Levels and Aging: A Key Assumption Challenged

A new study challenges one of the biggest assumptions behind NAD boosters: Do NAD+ levels really decline with age? Explore the latest findings in our NAD Boosters Review, which includes our tests and Top Picks for the NAD Boosters NADH, nicotinamide riboside (NR), and nicotinamide mononucleotide (NMN).

Read more about NAD Levels and Aging: A Key Assumption Challenged

Clinical Update

12/10/2021

64% of NMN Supplements Fail Tests

Fourteen of the 22 most popular NMN supplements (which can boost NAD+ levels) on Amazon were recently discovered to contain no detectable NMN. See the results in the Update to our NAD Boosters Review, which includes CL's tests of additional NMN, NADH, and nicotinamide riboside supplements, as well as our Top Picks.

Read more about 64% of NMN Supplements Fail Tests

Product Update

9/29/2025

NMN Allowed in Supplements

The FDA has changed course on NMN which, earlier, it had said should not be sold as a dietary supplement. Get the details in our NAD Booster Supplements Review, which includes our Top Picks for NAD+/NADH, nicotinamide riboside, and NMN.

Read more about NMN Allowed in Supplements

Clinical Update

5/21/2025

Nicotinamide Riboside for Cognition?

Does taking nicotinamide riboside (an "NAD Booster" also known as NR) improve cognitive function in people with peripheral artery disease? See what a recent study found in the Nicotinamide riboside section of our NAD Booster Supplements Review, which includes our Top Picks for NAD+/NADH, nicotinamide riboside, and NMN.

Read more about Nicotinamide Riboside for Cognition?

Clinical Update

11/17/2025

A Supplement for Long COVID?

Did nicotinamide riboside (an NAD booster) improve symptoms like “brain fog” in people with long COVID? See the study results in our NAD Boosters Review, which includes our Top Picks for NAD, NADH, nicotinamide riboside, and NMN.

Read more about A Supplement for Long COVID?

Product Update

3/19/2026

Niagen Overhyped

The maker of Niagen (a supplement containing nicotinamide riboside) was recently challenged regarding several of its marketing claims. Find out why, and how the company responded, in our NAD Boosters Review, which includes our Top Picks for NAD/NADH, nicotinamide riboside, and NMN.

Read more about Niagen Overhyped

Product Update

4/20/2026

NR: Many Don’t Match the Label

Testing found only 26 of 70 NR (nicotinamide riboside) supplements near their label claim – and many had little to none. For details, see our NAD Booster Supplements Review, which includes our Top Picks for NAD/NADH, nicotinamide riboside, and NMN.

Read more about NR: Many Don’t Match the Label

Clinical Update

8/12/2025

Many NAD Fail Tests

Recent tests of popular NAD+ supplements revealed that half of the products contained hardly any NAD+. For details by brand, see the Quality Concerns section of our NAD Booster Supplements Review. Also see our Top Picks among NAD boosters (including NMN and nicotinamide riboside).

Read more about Many NAD Fail Tests

Product Update

10/20/2025

Misleading Liposome Labels

Some "liposomal" supplements may not deliver what their labels proclaim. See an example in our NAD Booster Supplements Review, which includes our Top Picks for NAD+/NADH, nicotinamide riboside, and NMN. Also learn 8 Red Flags with Supplements.

Read more about Misleading Liposome Labels

CL Answer

Are David Beckham’s IM8 Supplements Worth Taking?

IM8 markets two main products that claim to help you "feel amazing today," and "stay young tomorrow." Find out if these products work and if we think they're worth the cost.

IM8

CL Answer

Is it okay to take vitamin D3 and fish oil together?

Find out if taking vitamin D and fish oil is okay, how it effects absorption, and the best way to take vitamin D to improve absorption. ConsumerLab.com's answer explains.

hand holding vitamin D and fish oil capsules

Product Update

5/26/2026

How Much NMN is Safe?

Most supplements that provide NMN – an NAD booster -- deliver amounts of niacin that would normally exceed tolerable limits. Does that make NMN unsafe? Learn what an expert panel concluded in our NAD Boosters Review + see our Top Picks among tested products.

Read more about How Much NMN is Safe?

Clinical Update

10/01/2026

Can NMN Improve Strength and Metabolism as You Age?

Does taking NMN help with strength, hearing, blood sugar, cholesterol, or body composition in older people? See what the latest evidence shows in our NAD Boosters Review + see our Top Picks for NMN, NAD+, and other NAD boosters.

Read more about Can NMN Improve Strength and Metabolism as You Age?

News Release

November 05, 2021

NAD Boosters for Energy and Memory? ConsumerLab Reviews NAD+, NAHD and NMN Supplements

White Plains, New York, November 5, 2021 — Most cells in the body use NAD (nicotinamide adenine dinucleotide) in the process of energy production, and compounds that boost blood levels of NAD are often sold in supplements marketed for a wide range of benefits, from increasing energy and ...

Clinical Update

4/19/2024

NMN and Kidney Injury

New laboratory research suggests that long-term supplementation with NMN might cause kidney injury in older people. Learn more in the Concerns and Cautions section of our NAD Booster Supplements Review.

Read more about NMN and Kidney Injury

Clinical Update

11/15/2022

NMN Can No Longer Be Sold as a Supplement

The FDA recently took the position that NMN, an NAD booster, cannot be sold as a dietary supplement. For details, see the NAD Boosters Review.

Read more about NMN Can No Longer Be Sold as a Supplement

Clinical Update

1/20/2025

Nicotinamide Riboside for Cognition?

Did nicotinamide riboside improve memory, attention or cognition among older people with cognitive decline in a recent study? Find out in the Nicotinamide riboside section of our NAD Booster Supplements Review, which includes our Top Picks for nicotinamide riboside.

Also see: Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?

Read more about Nicotinamide Riboside for Cognition?

Clinical Update

5/13/2022

New Nicotinamide Riboside Top Pick

We recently tested and Approved a nicotinamide riboside supplement that provides the most-studied form of nicotinamide riboside and is our new Top Pick for nicotinamide riboside in our NAD Booster Review.

Read more about New Nicotinamide Riboside Top Pick

Clinical Update

1/13/2021

Nicotinamide Riboside to Slow Aging and Reverse NAD+ Decline?

Nicotinamide riboside, a form of niacin, has been promoted to slow aging, partially based on the belief that it raises NAD+ levels that fall with age. A new study raises doubts about this. Get the details in the Niacin section of our B Vitamin Supplement Review. Also, learn about a concern with taking too much nicotinamide riboside.

Read more about Nicotinamide Riboside to Slow Aging and Reverse NAD+ Decline?

Clinical Update

2/28/2023

Nicotinamide Riboside for Alzheimer's?

A preliminary clinical study suggested that taking nicotinamide riboside reduced blood markers of Alzheimer’s disease. For details, see the What It Does section of our NAD Boosters Review, which includes our Top Pick among nicotinamide riboside supplements.

Also see: Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?

Read more about Nicotinamide Riboside for Alzheimer's?

Clinical Update

12/12/2023

Nicotinamide Riboside Side Effects

What are the common side effects of nicotinamide riboside (found in Tru Niagen), and is it safe? Find out what a recent study showed in the Concerns and Cautions section of our NAD Booster Supplements Review. Also see our Top Picks for nicotinamide riboside and other NAD boosters.

Read more about Nicotinamide Riboside Side Effects

Clinical Update

2/13/2024

Supplement for Cognition?

Does taking nicotinamide riboside improve cognitive or physical function among older people with mild cognitive impairment? See what a recent study showed in the Nicotinamide riboside section of our NAD Booster Supplements Review. Also see our Top Pick for nicotinamide riboside.

Also see our article about supplements for memory and cognition.

Read more about Supplement for Cognition?

Clinical Update

6/18/2024

Nicotinamide Riboside for Peripheral Artery Disease?

Does taking nicotinamide riboside improve physical capabilities in people with peripheral artery disease? Find out what a recent study found in the Nicotinamide riboside section of our NAD Booster Supplements Review, which includes our Top Picks among products.

Read more about Nicotinamide Riboside for Peripheral Artery Disease?

Clinical Update

10/08/2026

Nicotinamide Riboside for Parkinson’s?

A large study tested whether nicotinamide riboside eases Parkinson’s symptoms. See the results in our NAD Booster Supplements Review + see our Top Picks for nicotinamide riboside and other NAD boosters.

Read more about Nicotinamide Riboside for Parkinson’s?

Clinical Update

6/11/2026

Is Niacinamide Worth Considering for Skin Cancer Risk?

High-dose nicotinamide (a common form of niacin) may reduce the risk of skin cancer -- and even the cost of healthcare -- according to a new analysis. Learn more in the Niacin section of our B Vitamin Supplements Review, which includes our Top Picks for niacin/nicotinamide and other B vitamins.

Read more about Is Niacinamide Worth Considering for Skin Cancer Risk?

Clinical Update

9/19/2025

Niacin May Reduce Skin Cancer?

Taking high-dose nicotinamide (a common form of niacin) may reduce the risk of certain types of skin cancer, according to a new study. Get the details in the Niacin section of our B Vitamin Supplements Review, which includes our Top Picks for niacin/nicotinamide and other B vitamins.

Read more about Niacin May Reduce Skin Cancer?

Clinical Update

2/03/2023

Niacin & Cancer?

The NAD booster, nicotinamide riboside, might promote growth of existing cancers. Is there similar risk with niacin and niacinamide (nicotinamide)? Find out what evidence suggests in the Concerns and Cautions section of our NAD Booster Supplements Review.

Also, see our Top Pick among niacin supplements in our B Vitamin Supplements Review.

Read more about Niacin & Cancer?

Clinical Update

1/20/2025

Nicotinamide for Glaucoma?

Some preliminary research suggests nicotinamide (a form of niacin) may help with glaucoma, but is this recommended? Find out in our B Vitamins Supplements Review, which includes our Top Picks among B vitamin supplements.

Read more about Nicotinamide for Glaucoma?

Clinical Update

10/09/2021

Niagen for Energy?

The maker of Niagen (a supplement containing nicotinamide riboside) was challenged regarding its claim that Niagen boosts energy and performance. See how the company responded in the Nicotinamide Riboside section of our B Vitamins Supplements Review.

Read more about Niagen for Energy?

Clinical Update

4/03/2018

What Niagen Does

Niagen (nicotinamide riboside) has been promoted as an anti-aging supplement. Find out what's been shown in clinical studies, including one published recently, in the Niacin section of the B Vitamin Supplements Review.

Read more about What Niagen Does

Clinical Update

7/10/2018

Niagen for Blood Sugar Control?

Niagen, a brand of nicotinamide riboside (a form of niacin), was recently tested in a clinical trial to control blood sugar levels. Get the results in the Niacin section of the B Vitamins Review. (Also see our Top Picks among niacin supplements.)

Read more about Niagen for Blood Sugar Control?

Clinical Update

6/19/2019

NAD+ and Cancer?

Supplements that raise NAD+ levels in the body have been promoted for anti-aging effects. But there is a theoretical risk that they could stimulate cancerous cells, and a CL member reported this week that a supplement containing such an ingredient, nicotinamide riboside, appeared to increase his PSA level. Learn more in the Niacin section of the B Vitamin Supplements Review.

Read more about NAD+ and Cancer?

Clinical Update

7/20/2019

Is Niagen Safe?

Niagen (nicotinamide riboside) was recently studied for its safety and ability to raise NAD+ in the body. See the results and learn more about this form of niacin (which is also in the product Basis) in the Niacin section of the B Vitamin Supplements Review. Also see our Top Picks for niacin and other B vitamin supplements.

Read more about Is Niagen Safe?

Clinical Update

11/15/2022

NAD Booster & Cancer Risk

The NAD booster, nicotinamide riboside, increased the spread of certain aggressive cancers in a recent laboratory study, adding to existing concerns. Get the details in the Concerns and Cautions section of our NAD Booster Supplements Review.

Also, see our CL Answer about vitamins and cancer risk.

Read more about NAD Booster & Cancer Risk

Clinical Update

3/03/2025

Counterfeit Supplements

Twenty-nine out of 39 supplements containing the "NAD booster" nicotinamide riboside were recently found to contain much less ingredient than claimed, with many containing under 1%. Counterfeit versions of Tru Niagen were also identified. Details are in our NAD Booster Supplements Review, which includes our Top Picks among products.

Also see our article about avoiding counterfeit supplements online.

Read more about Counterfeit Supplements

Clinical Update

5/22/2025

Niacin for Skin Cancer

Some research suggests that taking high-dose niacin (as nicotinamide, also called niacinamide) can reduce skin cancer risk. Learn more about this (and an observational study of its safety) in the Niacin section of our B Vitamins Review, which includes our Top Picks for niacinamide supplements and other B vitamins.

Read more about Niacin for Skin Cancer

Clinical Update

6/25/2026

Does an NAD Booster Boost Cognition?

Does the NAD booster nicotinamide riboside help in people with mild cognitive impairment? See the latest findings in our NAD Boosters Review + see our Top Picks among NAD boosters.

Read more about Does an NAD Booster Boost Cognition?

Clinical Update

7/23/2026

NAD Booster for Boosting Memory?

Did nicotinamide riboside improve memory in people with mild cognitive impairment? See what a recent study found in our NAD Booster Supplements Review + see our Top Picks for NAD boosters.

Read more about NAD Booster for Boosting Memory?

Product Update

5/28/2026

Is This NAD Booster Overhyped?

The maker of Tru Niagen (which contains the NAD booster nicotinamide riboside) challenged recommendations that it stop making certain health-benefit claims. Find out how a review board responded in our NAD Boosters Review + see our Top Picks among NAD Boosters.

Read more about Is This NAD Booster Overhyped?

Recalls & Warnings

December 01, 2020

Niagen Cannot Be Promoted to Prevent or Treat COVID-19, Warns FDA

On November 17, 2020, the FDA issued warning letters to the sellers of Niagen and Nadovim, supplements that contain different forms of niacin, for selling products with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

May 09, 2020

FDA Warns Sellers of Essential Oils, CBD, Vitamins, and More Promoted to Treat Coronavirus

Between May 7 and May 8, 2020, the FDA issued warning letters to seven companies for selling products such as essential oils, CBD, hand sanitizers, and vitamins with unsupported claims that they can treat coronavirus (COVID-19).