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CoQ10 and Ubiquinol Supplements Review

Find the Best CoQ10 and Ubiquinol Supplements and Learn What They Do

Medically reviewed and edited by Tod Cooperman, M.D.

Last Updated

: 10/18/2021 | Initially Posted: 09/11/2021

CoQ10 and Ubiquinol Supplements Reviewed by ConsumerLab.com

Alphabetical list of CoQ10 and ubiquinol supplements compared in this review

ActiveQ Ubiquinol 50 mg

Bluebonnet Ubiquinol 100 mg

ChewQ 100 mg

Doctor's Best High Absorption CoQ10 With BioPerine

Dr. Mercola Liposomal CoQ10

Dr. Sinatra Omega Q Plus Max

Finest Nutrition [Walgreens] CoQ-10

Garden of Life RAW CoQ10 200 mg

H2Q

Healthy Origins Natural Ubiquinol

Kirkland Signature [Costco] Maximum Potency CoQ10 300 mg

Life Extension CoQ10 100 mg with PQQ

LiQsorb

Mary Ruth's CoQ10 Gummies - Raspberry

Mito-Medica H2Q 200 mg

Nano Food Wonder Heart Liposomal CoQ10 - Raspberry Flavor

Natural Factors Ubiquinol Active CoQ10 100 mg

Nature's Bounty CoQ-10 200 mg

NOW Extra Strength Ubiquinol 200 mg

Nutrifii Omega-Q

Premier Research Labs CardioVen

Pure Encapsulations CoQ10 60 mg

Puritan's Pride Q-Sorb CoQ-10 200 mg

Qgel 200 Double Strength Coenzyme Q10 200 mg

QGel ETS

Qgel LiQH

Qunol Mega CoQ10 Ubiquinol

Qunol Ultra CoQ10

Spring Valley [Walmart] CoQ10 200 mg

The Vitamin Shoppe Triple Strength Ubiquinol CoQ-10

USANA Coquinone 30

VetriScience Coenzyme Q10 10 mg - For Dogs + Cats

Vitafusion CoQ10 - Natural Peach Flavor

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Summary

What are the health benefits of CoQ10 and ubiquinol? People often take CoQ10 to offset a decline in natural levels that occurs with the use of statin (cholesterol-lowering) medication. Some take it to feel more energized or for a variety of other purposes. It may also modestly help with elevated cholesterol levels, migraine, and other conditions. The evidence supporting these uses remains preliminary, although it does benefit people with congestive heart failure (see What It Does). After being absorbed into the body, more than 90% of CoQ10 is converted to its active form, known as ubiquinol (CoQH2-10), which is also available as a supplement and appears to have greater bioavailability (i.e., it raises blood levels more) (see What It Is).
How much CoQ10 or ubiquinol should I take? CoQ10 and ubiquinol are typically taken at a dose of 50 to 200 mg per day, although higher doses have been used (see Dosage).
What did CL's tests of CoQ10 show? In laboratory testing, all of the products were shown to provide their listed amounts of CoQ10 or ubiquinol, which is an improvement over the results of our previous review. Cost comparisons, based on a 100 mg dose, showed you could spend as little as 8 cents to over $6 for an equivalent amount of CoQ10, and from 34 cents to $1.18 for ubiquinol (See What CL Found).
Best CoQ10 supplement? Among 33 CL Approved products, CL selected several Top Picks for regular as well as bioavailability-enhanced CoQ10 and ubiquinol supplements, each providing high quality CoQ10 or ubiquinol at very good value.
How to take CoQ10? Gastrointestinal side-effects may occur but can be minimized by breaking up the dose throughout the day, although it may interfere with sleep if taken before bed. CoQ10 and ubiquinol are best absorbed when taken with or shortly after a fatty meal, although certain forms can be taken without fats (see Absorption and Bioavailability Enhancers).
CoQ10 safety and side effects: At typical doses, CoQ10 and ubiquinol appear to be generally safe, but there are possible interactions with blood thinners and diabetes medications (see Concerns and Cautions).

You must be a member to get the full test results along with ConsumerLab.com's recommendations and quality ratings. You will get results for 15 CoQ10 and ubiquinol supplements selected by ConsumerLab.com and 18 others that passed testing in its voluntary Quality Certification Program. In this comprehensive review, you'll discover:

Which CoQ10 and ubiquinol supplements failed testing and which passed
CL's Top Picks, representing the best CoQ10 and ubiquinol supplements at lowest cost
Which supplements have special ingredients which may increase their absorption (such as polysorbate 80) and/or bioavailability (such as black pepper extract) — and the pros and cons of these formulas