Answer: Curcumin is fat-soluble, so if you take regular curcumin with just water, you will absorb very little. Consequently, it is best to take curcumin with a fatty meal. In addition, curcumin has a short-half life, i.e., it does not stay in body. As a result, to keep levels up, it is best to take curcumin twice daily. This is discussed in the Best Way to Take Curcumin and Turmeric section of the Curcumin and Turmeric Supplements and Spices Review.
Formulated curcumin products such NovaSol, CurcuWIN, Meriva, Theracurmin, and products that contain Bioperine (black pepper extract) can increase the half-life and bioavailability of curcumin (see the Absorption and Bioavailability section of the Curcumin and Turmeric Supplements Review.)