Do Probiotics, Such as Those by Bioma and Pendulum, Boost GLP-1 to Help with Weight Loss?

Medically reviewed and edited by Tod Cooperman, M.D.

Written by Meredith A. Worthington, Ph.D.

Published September 25, 2025

Answer:

Although some probiotic strains have been shown to temporarily and indirectly increase levels of glucagon-like peptide-1 (GLP-1), a natural hormone involved in blood sugar and appetite control, there is conflicting evidence about whether probiotics can significantly reduce body weight. In contrast, GLP-1 agonists like Wegovy and Ozempic are long-lasting and act directly on the GLP-1 pathway, making them more potent than probiotics.

Sign in as a member for more details. Products discussed include Pendulum Glucose Control, Pendulum GLP-1 Probiotic, and Bioma Gut Health Probiotics.

Also see our Probiotics Review, which includes our test results for supplements from Pendulum and many other brands, as well as our article about the probiotic Akkermansia muciniphila, which includes information about its safety and other possible health effects.

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