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Melatonin Supplements

Melatonin Supplements Reviewed by ConsumerLab.com

Find the best melatonin supplement based on independent tests and reviews by ConsumerLab.com covering best quality, dose and price. Includes what melatonin can and cannot do, product comparisons, dose, and melatonin side effects.

Melatonin Supplements Review

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CL Answer

What is the best way to take melatonin to get a good night's sleep?

Learn more about the best way to take melatonin for better sleep. When to take it, how to take it, and general melatonin information.

Melatonin Supplements Reviewed by ConsumerLab.com

CL Answer

Do melatonin supplements reduce the body's own production of melatonin?

Find out if taking melatonin supplements can decrease the body's own natural production of melatonin (endogenous melatonin), plus other factors that can decrease melatonin levels. ConsumerLabcom's answer explains.

Effects of melatonin supplements on the body's own production of melatonin -- melatonin capsules, glass of water, eye mask

CL Answer

What are the side effects of melatonin supplements?

Melatonin side effects - are there any? Read about drowsiness, dizziness, headache, nausea, mood & behavior, the risk of fractures and others. ConsumerLab.com's answer explains.

Melatonin Supplements Reviewed by ConsumerLab.com

CL Answer

Can melatonin help with stomach pain?

Find out if melatonin supplements can help with stomach pain, ulcers, reflux and dyspepsia, or if it can cause stomach upset.

Melatonin and Stomach Pain -- women with stomach pain

CL Answer

Do pistachio nuts really provide as much melatonin as supplements?

Find out if pistachio nuts, or other nuts such as Brazil nuts, cashews, peanuts and others, provide enough melatonin to help with sleep with effects similar to melatonin supplements. ConsumerLab.com's answer explains.

Melatonin in pistachio nuts -- bowl of pistachio nuts

CL Answer

I take melatonin to help me fall asleep. Are there any drugs that interact with melatonin that I should be aware of ?

Melatonin interactions with drugs, including blood pressure medications, Xanax, Ambien, antidepressants, caffeine and more.

CL Answer

Can melatonin supplements cause depression or make depression worse?

Find out if melatonin supplements can cause depression or make depression worse. ConsumerLab.com's answer explains.

Depressed Man Lying in Bed

CL Answer

I've heard that melatonin may increase the risk of broken bones. I take melatonin regularly. Should I be concerned?

Learn more about how melatonin may affect bone density and risk of fracture.

Melatonin Supplements Reviewed by ConsumerLab.com

CL Answer

Is it safe to take melatonin when taking prescription sedatives or sleep aids like lorazepam (Ativan) or zolpidem (Ambien)?

Safety information on taking melatonin while using prescription sedatives or sleep aids like lorazepam (Ativan) or zolpidem (Ambien).

CL Answer

Do any supplements help with COVID-19? Do supplements like vitamin D, zinc, vitamin C, or herbals work?

Find out if natural remedies & supplements for coronavirus such as zinc, vitamin C, garlic, or elderberry help to prevent or treat COVID-19.

Supplements for Coronavirus (COVID-19)? -- mask and pills

CL Answer

I've heard that taking vitamin D can reduce your natural production of melatonin and interfere with sleep. Is this true?

Can Vitamin D interfere with your body's melatonin production, and can taking vitamin D interfere with sleep?

Vitamin D

CL Answer

Which supplements have been shown to be helpful for autism?

Find out which supplements may help reduce symptoms of autism, including multivitamins, probiotics, and melatonin.

Bottle and Pills Spread Out on Blue Background

CL Answer

What are the best supplements or lifestyle modifications for insomnia, and which can make insomnia worse?

Find out which vitamins may help you sleep and learn if any vitamins or supplements can cause insomnia.

News Release

2/25/2022

Top-rated Vitamin and Supplement Brands and Merchants for 2022 Based on Consumer Satisfaction

White Plains, New York, February 25, 2022 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 8,049 responses collected in November/December 2021.

News Release

2/24/2022

Consumers Returned to Pre-Pandemic Supplement Usage in 2021, ConsumerLab Survey Reveals

White Plains, New York, February 24, 2022 —A survey of 8,049 people who use dietary supplements shows many supplements that declined in use in 2020 began bouncing back in 2021, such as magnesium (+2.4 percentage points), and CoQ10 (+2.7 pts).

News Release

2/26/2021

COVID Changed Supplement Popularity in 2020, ConsumerLab Survey Reveals

White Plains, New York, February 26, 2021 — A survey of 9,647 people who use dietary supplements shows that the supplements which experienced the greatest growth in popularity in 2020 were those being promoted to prevent or treat infection with SARS-CoV-2, the coronavirus that causes COVID-19.

Clinical Update

3/03/2015

Caution Urged with Melatonin

In light of increasing use of melatonin in children, an expert is cautioning that its long-term safety has not been established and it should be used carefully. For more about this -- as well as other concerns with melatonin, its efficacy, and our reviews of melatonin supplements, see the Melatonin Supplements Review >>

Clinical Update

6/07/2015

Melatonin Increases Bone Density

Research has begun to suggest that melatonin may have a positive effect on the skeleton. The latest study shows that giving post-menopausal women with bone loss daily melatonin causes small, but significant improvements in bone density. Details, including dosage, as well as our tests of melatonin supplements, are found in the Melatonin Supplements Review >>

Clinical Update

11/29/2015

Melatonin for Itchy Skin

Atopic dermatitis is an itchy inflammation of the skin, affecting up to 10% of adults and 30% of children. A recent study in children and adolescents with atopic dermatitis found that taking melatonin modestly reduced symptoms and, not surprisingly, reduced the time needed to fall asleep. For details about this and other uses of melatonin, as well our reviews of available melatonin supplements (including several similar to the one studied), see the Melatonin Supplements Review >>

Clinical Update

11/27/2018

Melatonin for Headaches

Recent reports suggest that melatonin, taken daily, may eliminate episodes of stabbing headache. Melatonin may also benefit people with migraine headache. For details, see the Headache section of the Melatonin Supplements Review. (Also see our Top Picks for melatonin.)

Clinical Update

11/07/2017

Melatonin Improves Sleep in Children with Autism

Prolonged-release melatonin helped children with autism fall asleep faster and stay asleep longer in a new study. Get the details, plus more about the best way to take melatonin to get a good night's sleep, in the "What It Does" section of the Melatonin Supplements Review >> [Also see our Top Picks for melatonin supplements in the Review.]

Clinical Update

10/08/2019

Melatonin & Post-Op Delirium

Reduced melatonin levels following surgery have been implicated in the development of post-operative delirium. But does taking melatonin around the time of surgery reduce this risk? Find out in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

8/21/2020

Caution With Melatonin & Diabetes

Research is raising concern regarding the use of melatonin by people with diabetes. For more details – as well as other concerns with melatonin – see the Concerns and Cautions section of the Melatonin Supplements Review. Also see our Top Picks for Melatonin.

Clinical Update

10/16/2020

Melatonin for Better Sleep

Can melatonin improve sleep in people hospitalized and receiving intensive care? See what a recent study found in the What It Does section of our Melatonin Supplements Review. Also learn about melatonin for improving sleep with other conditions, and see our Top Picks for melatonin.

Clinical Update

3/19/2021

Melatonin and Cancer

Can high-dose melatonin increase survival time or improve symptoms in people with advanced lung cancer? See what a new study found in the What It Does section of our Melatonin Supplements Review.

Also see results of a study in which melatonin was given during breast cancer treatment.

See our Top Picks among melatonin supplements.

Clinical Update

11/02/2021

Melatonin in Nuts?

Do pistachios or other nuts contain significant amounts of melatonin? How does roasting affect the melatonin content in nuts? See what a new study found in the ConsumerTips section of our Melatonin Supplements Review. Also see our Top Picks among melatonin supplements.

Clinical Update

11/05/2021

When Melatonin Does or Doesn't Help in Hospitals

See the latest research on whether or not melatonin helps people undergoing medical procedures or when hospitalized. Also learn if melatonin has been shown to help with other sleep issues. It's all in our Melatonin Supplements Review, which includes our Top Picks for melatonin.

News Release

2/25/2021

Top-rated Vitamin and Supplement Brands and Merchants for 2021 Based on Consumer Satisfaction -- Results of the ConsumerLab.com Survey of Vitamin & Supplement Users

White Plains, New York, February 25, 2021 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 9,647 responses collected in November 2020.

Clinical Update

6/06/2020

Melatonin for Sleep and Parkinson's

Melatonin is known to trigger sleep, but can it help people with Parkinson’s disease? See the results of the latest study in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

4/22/2020

Melatonin During Chemotherapy?

Does melatonin improve sleep quality and have other benefits during chemotherapy for breast cancer? Find out what a recent study showed in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

3/07/2020

Melatonin and Cataracts

Do you have cataracts (clouded lenses of the eye)? A recent study suggests that having them removed and replaced with a certain type of intraocular lens may increase natural melatonin production. For details, see the ConsumerTips section of the new Melatonin Supplements Review. Also see our Top Picks among melatonin supplements.

Clinical Update

8/29/2020

Melatonin for Nightshift Workers?

Does using melatonin before going to sleep in the morning improve attention and concentration in people working nightshifts? Find out what a recent study showed in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for Melatonin.

Clinical Update

6/20/2018

Melatonin for Poor Sleepers

For people who cannot fall asleep until early morning, a recent study showed some benefit with a low-dose form of melatonin. For details, see the What It Does section of the Melatonin Supplements Review. (Also see our Top Picks among melatonin supplements.)

Clinical Update

3/19/2019

Melatonin for Troubled Sleep?

Does melatonin supplementation help people with a condition involving intense dreams as well as laughing, yelling, kicking or punching during sleep? Learn what a recent study found in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

11/17/2018

Melatonin for Fibromyalgia

Daily melatonin supplementation has been found to decrease pain and improve other symptoms of fibromyalgia. For details, see the What It Does section of the Melatonin Supplements Review. (Also see our Top Picks for melatonin.)

Clinical Update

7/13/2018

Melatonin and Restless Legs Syndrome

Taking a melatonin supplement can help some people fall asleep, but a study suggests that it may be a problem for people with restless legs syndrome. Get the details, and learn about potential side effects of melatonin in the Concerns and Cautions section of the Melatonin Supplements Review.

Clinical Update

7/29/2017

Melatonin Increases Aggression

A study among young men found melatonin to modestly increase aggressive behavior. For more about this and other potential side effects of melatonin see the "Concerns and Cautions" section of the Melatonin Supplements Review (which also includes our Top Picks among products).

Clinical Update

1/28/2020

Is Melatonin Safe for Children?

Find out what side effects melatonin had when taken for up to two years by children and adolescents in a small study. See the What It Does section of the Melatonin Supplements Review. Also see our Top Pick for melatonin.

Clinical Update

6/02/2018

Melatonin and Balance

If you take melatonin, be aware that it can potentially affect balance for a period of time, as demonstrated in a recent study. For details, see the Concerns and Cautions section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

6/18/2019

Melatonin for PCOS?

Can melatonin help women who suffer from polycystic ovary syndrome (PCOS)? See what a recent study found in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

1/13/2017

Melatonin Quality Concern

A recent Canadian study found that 71% of melatonin supplements did not contain within 10% of labeled amounts of melatonin. Certain types were more likely to be off-the-mark than others. For details, and our own tests of (U.S.) products, see the "Quality Concerns" section of the Melatonin Supplements Review >>

Clinical Update

7/28/2018

Melatonin and Menopause

Can taking melatonin reduce the severity of menopause symptoms, such as difficulty sleeping, hot flashes, and sweats? Find out what a recent study showed in the What It Does section of the Melatonin Supplements Review. (Also see our Top Pick for melatonin.)

Clinical Update

10/03/2015

Melatonin Safety in Women

A year-long, placebo-controlled study in postmenopausal women found that moderate doses of melatonin resulted in no increase in daytime drowsiness or adverse events. Get more details and about this and other melatonin studies (and see tests of products) in the Melatonin Supplements Review >>

Clinical Update

9/05/2015

Melatonin for Anxiety Before Medical Procedures?

Some studies in men and women show that melatonin can reduce anxiety before surgery. A recent study in children found it can also reduce the anxiety and pain associated with blood tests. For details, including dosage, evidence for other uses of melatonin, and our tests of popular products, see the Melatonin Supplements Review >>

Clinical Update

7/13/2021

Melatonin and Autism

Can melatonin supplementation improve sleep, behavior, or mood in children with autism spectrum disorder? See what a new study found in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks among melatonin supplements.

Clinical Update

12/03/2021

Fracture Risk with Melatonin Supplements?

This week a newsletter reader asked if taking 3 mg of melatonin every night for sleep can increase the risk of fractures. Get the answer and find out why this is a valid concern in the Concerns and Cautions section of our Melatonin Supplements. Also see our Top Picks among melatonin supplements.

Clinical Update

3/06/2021

Melatonin After Stroke?

Melatonin supplementation may reduce the risk of developing delirium after a stroke, according to a new study. Get the details in the What It Does section of our Melatonin Supplements Review. Also see our Top Picks among melatonin supplements.

Clinical Update

6/08/2021

Melatonin & Weight

Can melatonin supplementation improve sleep or reduce weight? See what a new study among nightshift workers found in the What It Does section of the Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

12/20/2020

Melatonin for COVID-19?

Can melatonin reduce the duration of symptoms in people with COVID-19? Get the details in the COVID-19 section of our Melatonin Supplements Review. Also, see our Top Picks for melatonin.

Clinical Update

12/20/2020

Melatonin for Anxiety?

Can taking melatonin reduce anxiety before surgery? Find out what a recent analysis of studies showed in the What It Does section of the Melatonin Supplements Review. Also, see our Top Picks for melatonin.

Clinical Update

10/23/2020

Lower Dose Melatonin for Children

A new report suggests that very low doses of melatonin may be adequate to raise levels in children. For details, see the Dosage section of our Melatonin Supplements Review. Also see our Top Picks for low-dose melatonin.

Clinical Update

10/20/2020

Melatonin and COVID-19

Can melatonin supplementation reduce the risk of death in people with severe COVID-19? See what a recent study showed in the What It Does section of our Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

10/31/2020

Melatonin for Insomnia?

Can melatonin help middle-aged men and women with insomnia fall asleep faster or improve sleep quality? Find out what a new study showed in the What It Does section of our Melatonin Supplements Review. Also see our Top Picks for melatonin.

Clinical Update

2/11/2022

Melatonin & COVID

Can supplementing with melatonin help prevent death among people hospitalized with COVID-19? See what a recent study found in the COVID-19 section of our Melatonin Supplements Review, which includes our Top Picks for melatonin.

Also see our answer to the question: Do any supplements help with COVID-19?

Clinical Update

3/01/2022

Melatonin and Heart Palpitations?

Can taking melatonin cause heart palpitations? Find out in the Concerns and Cautions section of our Melatonin Supplements Review. Also see our Top Pick for melatonin.

Clinical Update

6/03/2022

Melatonin Poison Reports Jump

Reports to poison control centers regarding melatonin ingestion have skyrocketed in recent years among infants, children and adolescents. See the Concerns and Cautions section of our Melatonin Supplements Review for details and other potential safety issues with melatonin.

CL Answer

7 Supplements That May Help Treat Peptic Ulcers and 3 To Avoid

Peptic ulcers caused by H. pylori infection are typically treated with antibiotics, but certain supplements may also help. Find out which 7 supplements might be beneficial and which 3 should be avoided.

Supplements for peptic ulcer disease - young man with stomachache

CL Answer

What are the health benefits of tart cherry juice?

See the evidence for tart cherry juice health benefits from clinical studies. Find out if tart cherry has anti-inflammatory effects, if it can improve sleep, lower high blood pressure, or help for muscle pain and osteoarthritis.

Tart Cherry Benefits -- glass of cherry juice and two tart cherries

Clinical Update

1/21/2022

Melatonin, Sleep & Nighttime Asthma

There is some concern about the use of melatonin among people with nighttime asthma. Get the facts in the Concerns and Cautions section of our Melatonin Supplements Review.

Clinical Update

11/18/2021

Does Melatonin Increase Alzheimer’s Risk?

My doctor said that melatonin may increase the risk of Alzheimer's as some sleeping pills do. Is this true? See the answer in Concerns and Cautions section of the Melatonin Supplements Review.

Clinical Update

9/29/2015

Melatonin Helps Post-Op Sleep

A study found that giving melatonin to women significantly improved their sleep time during the weeks after breast cancer surgery. For details, including our tests of products, see the Melatonin Supplements Review >>

Clinical Update

11/05/2016

Melatonin for Migraine

Melatonin was shown to reduce migraine headaches as well as a prescription migraine drug but with fewer side-effects in a recent study. Get the details in the "What It Does" section of the Melatonin Supplements Review >>

Clinical Update

4/12/2017

Melatonin vs. Light Therapy for Sleep

A recent study found that melatonin was slightly better than light therapy in helping children fall asleep. The overall results, however, may have been better with a lower dose. For details see the "What It Does" section of the Melatonin Supplements Review >>

Clinical Update

6/21/2022

Melatonin for MS?

Can taking melatonin help people with multiple sclerosis (MS)? Find out what a recent study showed in the What It Does section of our Melatonin Supplements Review.

Also see our article about supplements for MS.

Clinical Update

5/27/2022

Melatonin and Urinary Frequency

Can melatonin supplementation decrease nighttime urinary frequency in older women? See what a recent study found in the Concerns and Cautions section of the Melatonin Supplements Review.

Clinical Update

9/28/2022

Better Sleep Habits Instead of Melatonin

An expert group is encouraging parents to improve sleep habits in children rather than give melatonin, citing potential safety concerns. Get the details in the What It Does section of our Melatonin Supplements Review.

Clinical Update

3/01/2022

Melatonin to Prevent COVID?

Does taking melatonin help prevent COVID-19? Find out what a study found in the COVID-19 section of our Melatonin Supplements Review.

Also see our article about Supplements for COVID.

CL Answer

I take omeprazole (Prilosec), a proton pump inhibitor, to reduce stomach acid. Are there supplements I should avoid, or be taking, due to this drug?

Supplement interactions with proton pump inhibitor (PPI) drugs like omeprazole (Prilosec) and Nexium.

CL Answer

Do any supplements or diets help prevent or treat osteoporosis?

If you have osteoporosis, you may be interested in supplements or diets for bone health. Find out which can increase bone strength and density.

Supplements and Osteoporosis

CL Answer

Supplements for multiple sclerosis (MS): Do any supplements reduce symptoms or relapse?

Find out if vitamins or supplements such as ginkgo, fish oil, biotin, vitamins A, C, E, D, and B12, or selenium reduce symptoms or relapse in people with multiple sclerosis (MS).

Older woman with multiple sclerosis who is experiencing back pain while sitting on her bed

CL Answer

Do supplements help with Parkinson’s disease treatment or prevention?

Learn what has been shown with vitamins D and E, niacin, CoQ10, melatonin, creatine, SAMe, NAC, valerian, CoQ10, and CBD, as well as with coffee and the Mediterranean and MIND diets for treating and/or preventing Parkinson's disease.

Elderly man with parkinsons holding trembling hand while eating

News Release

3/25/2020

Trouble Sleeping? ConsumerLab Tests Reveal the Best Melatonin Supplements

White Plains, New York, March 25, 2020 — Melatonin supplements can help you fall asleep faster, and some may help you stay asleep.

CL Answer

I have been having dizziness for the past few months and am wondering if it could be a side effect of supplements I take. Which supplements cause dizziness?

Find out which supplements that may cause dizziness, vertigo, or imbalance, including garlic, melatonin, saw palmetto, and red yeast rice.

Young Woman Helping Elderly Woman Remain Upright

CL Answer

Do any supplements or lifestyle changes reduce the symptoms of tinnitus? Is it true that some supplements can cause tinnitus?

Learn which supplements can ease tinnitus, including melatonin and pine bark extract. Understand which may actually cause tinnitus.

Supplements for Tinnitus -- Woman Holding Her Ears

Clinical Update

8/05/2022

Vitamin C or Melatonin for COVID?

Find out if supplementing with vitamin C or melatonin reduced symptoms in people with mild to moderate COVID in a recent study.

CL Answer

Which supplements may help with PCOS (polycystic ovarian syndrome)?

Many supplements are promoted to help treat symptoms of PCOS (polycystic ovarian syndrome), but do they really work? See the clinical evidence for inositol (myo-inositol and D-chiro-inositol), alpha lipoic acid, vitamin B-12, folic acid, vitamin D and more.

Supplements for PCOS

CL Answer

I have low blood pressure. Are there any supplements I should avoid?

Find out which supplements can cause decreases in blood pressure, including melatonin, arginine, magnesium, and calcium.

Woman Checking Blood Pressure

CL Answer

Are there any supplements I should avoid when taking Valium or Xanax?

Find out which supplements should be avoided when taking benzodiazepines like Valium, Xanax, and Ativan.

Supplements to avoid with Valium or Xanax

CL Answer

Is it okay to crush a tablet and consume the powder or add the powder to food, rather than swallowing the tablet whole?

Find out if it is safe to crush supplements and ingest the powder with food or if it is better to swallow the tablet whole.

Whole Tablets and Crushed Tablet on Blue Table

CL Answer

Do any supplements help prevent or treat a cold?

Are there supplements that can help prevent or treat cold symptoms? Learn more about zinc, probiotics, vitamin C and more.

Supplements for Colds: Zinc, Echinacea & More -- Couple with cold, sitting on couch blowing their noses

News Release

2/25/2020

Top-rated Vitamin and Supplement Brands and Merchants for 2020 Based on Consumer Satisfaction -- Results of the ConsumerLab.com Survey of Vitamin & Supplement Users

White Plains, New York, February 25, 2020 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 9,782 responses collected in late November and early December 2019.

CL Answer

Do any supplements help for irritable bowel syndrome (IBS)?

IBS supplements may help reduce irritable bowel symptoms such as pain, diarrhea and constipation. Supplements include probiotics, melatonin, and flaxseed.

Supplements for IBS? -- Women With Stomach Pain

CL Answer

Are light boxes effective for preventing and treating seasonal affective disorder (SAD), also known as "winter depression," or circadian rhythm disorders such as jet lag? Which light boxes are best?

Learn about the benefits and safety of light boxes (including who is most likely to benefit), how to use these devices, which commercially available products appear to meet the technical requirements, and who should not use light boxes.

Man reading a book while sitting in front of a light box

News Release

2/25/2019

Top-rated Vitamin and Supplement Brands and Merchants for 2019 Based on Consumer Satisfaction -- Results of the ConsumerLab.com Survey of Vitamin & Supplement Users

White Plains, New York, February 25, 2019 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 10,931 responses collected in late November and early December 2018.

CL Answer

Which supplements are helpful to have when traveling? Any tips on how to best store supplements on trips?

Find out which vitamins & supplements can be helpful when traveling, including melatonin, ginger, and more, and find out how you can carry them with you.

CL Answer

Which vitamins and minerals should be taken together or separately?

Find out the best way to take vitamins and minerals and which vitamins and minerals should be taken together or separately for proper absorption. ConsumerLab answer explains the best way to take vitamins and minerals.

Vitamins & Minerals That Should Be Taken Together or Separately -- various vitamins in spoons

CL Answer

9 Supplements That May Help Reduce Nighttime Urination (And 4 That Might Not Help)

Waking up more than once during the night to use the bathroom? Learn more about the 9 supplements that may help and 4 others that don't.

A toilet in an empty bathroom at night

CL Answer

Which supplements help to improve energy and decrease fatigue?

Energy supplements and vitamins - Some can help increase energy and reduce fatigue, including CoQ10, curcumin/turmeric, cocoa, and B vitamins.

Supplements to Improve Energy and Decrease Fatigue -- tired woman yawning at desk

CL Answer

What is GABA (gamma-aminobutyric acid)? Is it beneficial for stress, anxiety, insomnia or other conditions, and is it safe?

Find out about GABA (gamma-aminobutyric acid), including if it's beneficial for insomnia, epilepsy, stress and anxiety, high blood pressure and building muscle, and learn if taking GABA supplements is safe.

Older women sitting calmly on a couch with her hands behind her head and her eyes closed

CL Answer

Are there supplements, foods, or beverages that I should avoid when taking clopidogrel (Plavix)?

Learn about supplement interactions with clopidogrel (Plavix). Supplements that may interact with this medication include cannabidiol (CBD), grapefruit, St. John's wort, ginkgo and others.

CL Answer

Is it dangerous to use certain herbals, vitamins, or other dietary supplements when breastfeeding?

Find out which supplements should be avoided when breastfeeding, including medicinal herbs, soy, and flaxseed.

Herbs and Supplements to Avoid When Breastfeeding

CL Answer

How much should I expect to pay for supplements? Are higher-priced supplements any better than low-priced brands?

Learn about the cost of supplements. Info including the best pricing on fish oil, CoQ10, vitamins C & D, magnesium, and calcium.

Cost and Quality of Dietary Supplements -- supplement bottles on store shelves

CL Answer

What is Perque Bone Guard Forté? It is safe and effective for bone health?

Find out about the ingredients in Perque Bone Guard Forté, including which ingredients may be beneficial for osteoporosis and bone health and which may be a safety concern.

Bottle of Perque Bone Guard Forte

CL Answer

Do any supplements improve balance or reduce the risk of falls?

Find out which vitamins & supplements may improve your balance to help reduce the risk of falling, including vitamin D and protein.

Supplements to Improve Balance & Reduce the Risk of Falls -- older woman walking up stairs

CL Answer

Is it okay to crush or break vitamin pills to lower the dose or mix into food?

Learn about the safety of crushing vitamin pills, tablets, capsules or enteric-coated tablets and ingesting the powder with food, as opposed to taking a whole pill.

Is it okay to crush or cut supplement pills? -- Large, broken vitamin pill

Clinical Update

12/08/2016

Vitamin D Keeping You Up?

A study of women given daily doses of vitamin D found that those who achieved the highest blood levels of vitamin D experienced a deterioration in the quality of their sleep. This is consistent with an earlier study showing decreased production of melatonin with high-dose vitamin D. For details, see the "Concerns and Cautions" section of the Vitamin D Supplements Review >>

Clinical Update

1/04/2020

Foods That May Help Sleep

In addition to supplements like melatonin that can aid sleep, certain foods are associated with reduced risk of insomnia. We've added information about this to our answer to the question: Which supplements can help me sleep?

Product Review

L-Tryptophan and 5-Hydroxytryptophan (5-HTP) Supplements Review

Choose the Best L-Tryptophan and 5-HTP Supplements. CL Tests Identify High Quality L-Tryptophan and 5-HTP (5-Hydroxy-L-Tryptophan) at the Best Value.

L-Tryptophan and 5-HTP (5-Hydroxy-L-tryptophan) Supplements Reviewed By Consumerlab.com

CL Answer

Which supplements, foods or diet and lifestyle changes help relieve acid reflux (heartburn), and which worsen it?

Find out which supplements and foods can help relieve acid reflux, and which can make it worse.

Supplements Making Acid Reflux Worse -- Man with acid reflux pain

CL Answer

Are liquid or gummy vitamins better than tablets, capsules or softgels?

Find out if liquid or gummy vitamins and supplements are better than tablets, capsules or softgels, are better absorbed, or better for people who have had gastric bypass or who have other conditions.

Are Liquid Vitamins Better? -- liquid vitamin bottle and dropper

CL Answer

Are gummy vitamins better or worse than pills?

Learn more about gummy supplements, including those for multivitamins, vitamins C and D, calcium, and B vitamins.

Problems With Gummy Vitamins -- bottle of gummy vitamins

CL Answer

Can any supplements improve or worsen symptoms of fibromyalgia?

Find out if any supplements may help improve fibromyalgia symptoms, learn which supplements do not seem beneficial, and find out if any supplements worsen symptoms.

Woman holding her neck and lower back due to fibromyalgia pain

Recalls & Warnings

4/24/2021

Metal Reported in Church & Dwight Gummy Melatonin, Multis & Fiber Supplements

On April 20, 2021, Church & Dwight Co., Inc.

CL Answer

Do any supplements help for restless legs syndrome?

Find out whether supplements or vitamins like iron, magnesium, vitamin E and others can help for restless leg syndrome (RLS). ConsumerLab.com's answer explains.

Supplements for Restless Legs Syndrome

Product Review

Vitamin D Supplements Review (Including Calcium, Magnesium, Boron, and Vitamin K)

Find the Best Vitamin D Supplement with the Right Dose

CL Answer

Do any supplements, like Nervive, help with nerve pain, like sciatica or diabetic neuropathy?

Find out which supplements for nerve pain are effective. Sciatica & diabetic neuropathy may be helped, including fish oil and alpha-lipoic acid.

CL Answer

Do any supplements or foods benefit people with Crohn's disease? Are there any supplements that should be avoided?

Find out the most common vitamin and mineral deficiencies in people with Crohn's disease, including iron, B6, B12, vitamin D, zinc and others, plus evidence for N-acetyl-glucosamine (NAG), fish oil, and curcumin.

Supplements for Crohn's Disease -- Crohn's Disease Written on Notepad, Pills

CL Answer

Can taking too much vitamin B-6 be dangerous?

Find out if multivitamins contain excessive amounts of B-6, how much B-6 is too much, and symptoms of toxicity and overdose.

Vitamin tablets placed on a table to spell B6

CL Answer

Is it true that there is no point in taking fish oil supplements for heart health?

Taking fish oil for heart health may be a benefit. Learn more about omega fatty acids from fish oil and it's impacts.ains.

Fish Oil for Heart Health? -- fish oil capsules and stethoscope

Product Review

Magnesium Supplements Review (Including Calcium, Boron, and Vitamins D & K)

Find Out What Magnesium Does, Who Needs It, and Our Top Picks Among Supplements

CL Answer

What are the best supplements for depression and anxiety?

Best natural supplements for depression and anxiety, including the evidence for fish oil, vitamin D, probiotics, and herbal supplements for depression such as curcumin (from turmeric) and saffron.

Best Supplements for Depression and Anxiety -- sad young woman sitting on couch, looking toward the window

CL Answer

Risks of Too Many Vitamins & Supplements

Taking too many vitamin supplements -- or taking too much of a particular supplement -- can have short and long-term adverse effects.

Too Many Vitamins

CL Answer

Are there supplements I should avoid when taking apixaban (Eliquis) or similar blood thinner drugs like Xarelto?

Learn about supplement interactions with apixaban (Eliquis), rivaroxaban (Xarelto) and other blood thinner drugs in the direct factor Xa inhibitors class. Supplements that may interact with these medications include fish oil and St. John's wort. ConsumerLab.com's answer explains.

Eliquis Supplement Interactions -- box of Eliquis

CL Answer

What are the side effects of ashwagandha supplements?

Learn about the safety and side effects of ashwagandha supplements, including headache, sleepiness, upset stomach, blood pressure and more. ConsumerLab.com's answer explains.

ashwagandha side effects

CL Answer

Do hair loss supplements, such as Viviscal, Hair La Vie, and Nutrafol, or topical essential oils work?

Vitamins and supplements that may help with hair loss and thinning, including saw palmetto, beta-sitosterol, protein, iron, and vitamin D.

Supplements for Hair Loss -- woman looking at hairbrush

Recalls & Warnings

2/22/2021

FDA Warns Seller of Melatonin & Other Sleep Supplements

On February 18, 2021, the FDA issued a warning letter to SANA Group LLC following a review of the company's website, which found statements made about the company's products Sleep Sana Sleep Drops and Sleep Shots to be drug claims.

Recalls & Warnings

4/11/2015

FDA Warns Maker of "Relaxation" Drink

On March 4, 2015, the FDA issued a warning letter to Bebida Beverage Company (BeBevCo) following a review of the company's website and product label, which found the "relaxation beverage"Koma Unwind Liquid Relaxation to be adulterated because it contains melatonin.

Recalls & Warnings

4/09/2014

Maker of Relaxation Drink Warned For Melatonin Ingredient

On March 27, 2014, the FDA issued a warning letter to Dewmar International BMC, Inc. following a review of the company's product packaging and labels, which found the "relaxation beverage" Lean Slow Motion ...

Recalls & Warnings

8/20/2019

Seller of Liposomal Curcumin, Vitamin C & Melatonin Warned for Manufacturing Violations

On August 6, 2019, the FDA issued a warning letter to Let's Talk Health, Inc.

Recalls & Warnings

3/07/2012

Melatonin in Cookies and Drinks -- Not Allowed, Says FDA

On December 8, 2011 FDA issued a letter to Revolt Distribution, Inc. warning that their food and beverage products contain an unsafe food additive.

Recalls & Warnings

8/03/2011

FDA Calls "Melatonin Brownie" Unsafe and Sends Warning to Manufacturer

On July 28, 2011 the U.S. FDA sent a Warning Letter to the manufacturer of meltonin-containing "Lazy Larry" brownies, advising that the government considers them unsafe, illegal, and subject to seizure, giving the company fifteen days to respond.

News Release

2/25/2018

Top-rated Vitamin and Supplement Brands and Merchants for 2018 Based on Consumer Satisfaction

White Plains, New York, February 25, 2018 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 11,446 responses collected in late November and early December 2017.

Recalls & Warnings

2/14/2017

Life Extension Warned for Drug Claims

On February 1, 2017, the FDA issued a warning letter to Life Extension Foundation Buyers Club, Inc.

News Release

2/24/2018

Magnesium, Curcumin, and Apple Cider Vinegar Rise in Popularity, While Probiotics Dip and Calcium Continues to Decline in Latest ConsumerLab.com Survey of Supplement Users

White Plains, New York, February 24, 2018 — A recent survey of 11,446 people who use dietary supplements shows that magnesium and curcumin and turmeric have leapt into the top 5 most popular dietary supplements, just behind vitamin D, fish oil and CoQ10.

Recalls & Warnings

8/15/2020

FTC Warns 20 More Companies for Coronavirus Claims

On August 14, 2020, the FTC announced that it sent warning letters to 20 companies for selling products such as vitamin C, hydrochloroquine, omega 3, and melatonin with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

5/03/2013

Maker of Omega-3, Saw Palmetto, St. John’s Wort Supplements And More Warned For Manufacturing Violations and Drug Claims

On March 19, 2013, the FDA issued a warning letter to Sunset Natural Products Inc.

News Release

9/26/2017

ConsumerLab.com Explains How to Take Melatonin and Reveals Its Top Supplement Picks

White Plains, New York, September 26, 2017 — Melatonin is now one of the most popular supplements, largely due to its proven ability to trigger sleep.

News Release

2/24/2017

Vitamin D Supplements Maintain Top Spot in Popularity, as Probiotics Surpass Multivitamins to #4 Behind Fish Oil and CoQ10 in Latest ConsumerLab.com Survey

White Plains, New York, February 24, 2017 — A recent survey of over 9,505 people who use dietary supplements shows the most popular dietary supplement to be vitamin D, followed by fish oil, CoQ10, probiotics, and multivitamins.

News Release

2/24/2016

Vitamin D Supplements Jump to Top Spot in Popularity, Surpassing Fish Oil, as Probiotics Rise to #5 Spot Behind CoQ10 and Multivitamins in ConsumerLab.com Survey

White Plains, New York, February 25, 2016 — A recent survey of over 11,000 people who use dietary supplements shows the most popular dietary supplement to be vitamin D, followed by fish oil, CoQ10, multivitamins, and probiotics.

Recalls & Warnings

10/25/2016

FDA Warns Maker of Sublingual Melatonin and Progesterone Cream

On October 12, 2016, the FDA issued a warning letter to Threshold Enterprises, Ltd.

Recalls & Warnings

6/05/2020

LifeHealth Science Warned for Manufacturing Violations

On May 15, 2020, the FDA issued a warning letter to LifeHealth Science, which found the company's ORËÁ product to be adulterated because it was prepared, packed, or held under conditions that violate Current Good Manufacturing Practices for dietary supplements.

Recalls & Warnings

8/14/2020

The Green Herb and New Genesis Health Warned for Manufacturing Violations

On July 31, 2019, the FDA issued a warning letter to Davis Ventures, Inc.

Recalls & Warnings

9/01/2020

Custom Nutraceuticals, LLC Warned for Manufacturing Violations

On August 6, 2020, the FDA issued a warning letter to Custom Nutraceuticals, LLC, following a facility inspection which found the company's products, including Thermal Revolution Black, Anabolic Blackout Raspberry Lemonade, Militia Re-COMP, and Rhino Rampage Wildberry to be ...

Recalls & Warnings

7/11/2014

Maker of Cough and Sleep "Remedies" Warned for Drug Claims

On June 27, 2014, the FDA issued a warning letter to Zarbee's, Inc.

Recalls & Warnings

4/18/2013

Cardio, Energy and Sexual Enhancement Supplement Distributor Warned For Manufacturing Violations and Drug Claims

On December 21, 2012, the FDA issued a warning letter to ForMor Inc, dba ForMor International, following a facility inspection which found the company's Cardio Cocktail and Argenix dietary supplements to be adulterated because because they were prepared, packed, or held under conditions that do ...

News Release

5/28/2015

ConsumerLab.com Shows How to Choose the Right Melatonin Supplement for Sleep

White Plains, New York, May 28, 2015 — An estimated 60 million Americans experience insomnia each year, according to the National Institutes of Health, and they increasingly turn to the supplement melatonin for potential help. In fact, U.S. sales of melatonin increased 16.

News Release

2/28/2015

Use of Magnesium and Probiotics Rise, Multivitamins and Weight Loss Supplements Fall, According to ConsumerLab.com Survey

White Plains, New York, February 28, 2015 — A recent survey of over 10,000 people who use dietary supplements shows the most popular dietary supplement to be fish oil, followed by multivitamins, CoQ10, vitamin D, B vitamins, magnesium, calcium, probiotics, and vitamin C.

News Release

1/31/2013

Use of CoQ10, Digestive Enzymes, Probiotics and B Vitamins on the Rise According to ConsumerLab.com Survey

White Plains, New York — February 1, 2013 — A recent survey of over 10,000 people who take supplements shows that CoQ10, digestive enzymes, probiotics, and B vitamins are the four categories experiencing the most growth over the prior year.

Recalls & Warnings

12/11/2020

FDA Warns Seller of Curcumin and Cholesterol Supplements

On November 20, 2020, the FDA issued a warning letter to Natures Boost LLC following a review of the company's websites, which found statements made about the company's products Blood Boost Formula and Turmeric Curcumin to be drug claims.

Recalls & Warnings

9/11/2020

Seller of "COVID PACK" Warned for Coronavirus Claims

On September 9, 2020, the FDA issued a warning letter to Pharmacy Plus, Inc. dba Vital Care Compounder for selling COVID PACK and COVID 'POSITIVE' PACK products with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

5/23/2020

BIOTA Biosciences Recalls Injectable CBD and Curcumin Products

On May 20, 2020, BIOTA Biosciences LLC issued a recall of five lots of three injectable products because they were marketed without FDA approval.

Recalls & Warnings

4/25/2020

Injectable Curcumin, CBD Are Not Safe, Warns FDA

On April 9, 2020, the FDA issued a warning letter to BIOTA Biosciences LLC following a review of the company's website, which found statements made about some of the company's, products, including Canabidiol (CBD) Complex, Cannabidiol+Curcumin, and Curcumin Complex to be ...

Recalls & Warnings

3/31/2020

Bulletproof Warned for Manufacturing Violations

On March 20, 2020, the FDA issued a warning letter to Bulletproof 360, Inc.

Recalls & Warnings

10/08/2019

Seller of Tea, Colloidal Silver, Homeopathic Products Warned for Manufacturing Violations

On September 12, 2019, the FDA issued a warning letter to Herbal Healer Academy, Inc.

News Release

11/29/2011

ConsumerLab.com identifies many quality melatonin sleep supplements, but prices range from 4 cents to over $1 for the same dose

White Plains, New York — November 29th, 2011 — Can melatonin help you sleep? "Melatonin supplements may help some people get to sleep sooner, particularly those with chronic sleeping problems, but don't just buy any supplement - they vary significantly in strength, dosage, and cost," ...

News Release

10/02/2008

ConsumerLab.com finds melatonin supplements range in strength but ingredient quality is high

WHITE PLAINS, NEW YORK — OCTOBER 2, 2008 — ConsumerLab.com announced test results today from its new Product Review of Melatonin Supplements.  Melatonin supplements may help treat certain sleep disorders and disturbances, including jet lag.

News Release

9/17/2008

ConsumerLab.com's tests of menopause supplements reveal wide range in strength and quality; mislabeling and contamination discovered -- Soy and red clover isoflavones, black cohosh, and progesterone products tested

WHITE PLAINS, NY — September 17, 2008 — Risks associated with traditional hormone therapy for symptoms of menopause have increased public interest in alternative treatments, particularly dietary supplements. But a report today of recent tests by ConsumerLab.

News Release

8/12/2008

ConsumerLab.com finds improvements in labeling of nutrition bars but potential pitfalls exist -- New report compares 20 bars, including those for protein, fiber, energy and whole food

WHITE PLAINS, NY — August 12, 2008 — Labeling on nutrition bars has become more accurate, according to a new report by ConsumerLab.com.

News Release

8/05/2008

ConsumerLab.com Find Fifty Fish Oil Supplements Pass Quality Testing -- New Report Helps Consumers Choose Among Pills, Liquids, Foods and Beverages with Omega-3 Fatty Acids (EPA and DHA)

WHITE PLAINS, NEW YORK — AUGUST 5, 2008 — ConsumerLab.com announced today that testing of fifty omega-3 fish oil supplements, foods or beverages (including two marketed for pets) found all to have safe levels of mercury, lead and PCBs.

News Release

7/01/2008

Tests of ten red yeast rice supplements by ConsumerLab.com reveal significant statin levels, but some pills contaminated -- Popular cholesterol-lowering supplements compared in new report

WHITE PLAINS, NEW YORK — JULY 1, 2008 — ConsumerLab.

News Release

3/29/2006

ConsumerLab.com reports on 29 popular melatonin sleep supplements

WESTCHESTER COUNTY, NEW YORK — MARCH 29, 2006 (UPDATED APRIL 7, 2006) — ConsumerLab.com announced test results today from its new Product Review of Melatonin Supplements covering 29 products.

News Release

3/13/2006

ConsumerLab.com reports on supplements for bone health containing calcium and vitamin D— Results posted for 32 supplements for adults and children; One found contaminated with lead

WESTCHESTER COUNTY, NEW YORK — MARCH 13, 2006 — ConsumerLab.com announced test results today from its new Product Review of Supplements for Bone Health covering 32 adult and children's products containing calcium and vitamin D. Sales of calcium supplements in the U.S.

News Release

12/30/2002

Top quality melatonin products identified by ConsumerLab.com — Hormone supplement used to treat sleep disturbances due to jet travel and other causes

WHITE PLAINS, NY — December 30, 2002 — In its latest Product Review, ConsumerLab.com found that 16 of 18 melatonin dietary supplements met their label claims and were free of lead contamination.

Recalls & Warnings

6/20/2020

FTC Warns 30 More Companies for Coronavirus Claims

On June 18, 2020, the FTC announced that it sent warning letters to 30 companies for selling products such as immune system boosters, colloidal silver, vitamin C, and CBD with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

5/23/2020

FTC Warns 50 More Companies for Coronavirus Claims

On May 21, 2020, the FTC announced that it sent warning letters to 50 companies for selling products such as herbal products, immune system boosters, and vitamin C, with unsupported claims that they can treat coronavirus (COVID-19).

News Release

12/10/2002

Lupus patients cautioned about hormone supplement — ConsumerLab.com releases DHEA testing results online today

WHITE PLAINS, NY — December 10, 2002 — In its latest Product Review, ConsumerLab.com found that 3 of the 17 DHEA (dehydroepiandrosterone) supplement products it tested contained less than their claimed amounts of this hormone — one having less than one-fifth of what it claimed.

News Release

10/29/2002

Enormous variation found in strength of garlic supplements — most popular herb in U.S. — ConsumerLab.com releases results online today

WHITE PLAINS, NY — October 29, 2002 — ConsumerLab.com's Product Review of Garlic Supplements found strength to vary by as much as 1500% across products. Strength was based on each product's ability to generate allicin, a chemical associated with the efficacy of non-aged garlic.

News Release

9/24/2002

Problems found with most sexual enhancement supplements evaluated by ConsumerLab.com — Only 9 of 22 products pass independent review

WHITE PLAINS, NY — September 24, 2002 — ConsumerLab.com announced today that nearly 60% of products failed to pass its independent Product Review of Sexual Enhancement Supplements. Sexual dysfunction is estimated to affect 43% of women and 31% of men in the U.S.

Recalls & Warnings

12/26/2012

Seller of Blood Sugar, Depression and Sleep Supplements Warned For Making Drug Claims

On October 15, 2012, the FDA issued a warning letter to BioNeurix Corporation after statements found on the company's website, http://www.pharma-tree.com, were found to promote the dietary supplements Blood Sugar 360, Amoryn, Seredyn, and Mellodyn as drugs.

Recalls & Warnings

2/13/2019

Supplements Promoted for Alzheimer's Disease and Dementia Sell "False Hope," Warns FDA

On February 11, 2019, the FDA warned consumers to beware supplements promoted to prevent or treat Alzheimer's disease or dementia.

Recalls & Warnings

12/19/2020

FDA Finds Unapproved Drugs in Many Weight Loss and Sexual Enhancement Products Sold Online

On December 18, 2020, the FDA warned consumers that certain products promoted for weight loss, body building, sexual enhancement, pain relief, sleep, and other uses because may contain harmful ingredients.

Recalls & Warnings

7/27/2012

Prescription and Street Drug Alternatives Found in Male Enhancement, Mood, and Sleep Supplements

On July 10, 2012, the FDA issued a warning letter to Evol Nutrition Associates, Inc. subsequent to a 2011 inspection which found a number of the company's products contained prescription and investigational drugs and were misbranded.

Recalls & Warnings

5/14/2014

Maker of Mood, Smoking Cessation Supplements and More Warned for Violations, Drug Claims

On April 17, 2014, the FDA issued a warning letter to CDJ Holding, Incorporated, d.b.a.

Recalls & Warnings

8/08/2013

Sleep Supplement Recalled Due To Undeclared Drugs

On August 7, 2013, Health and Beyond LLC issued a voluntary recall of dietary supplement Tranquility because it was found to contain traces of undeclared drugs, Doxepin and Chlorpromazine.

Recalls & Warnings

3/28/2011

FDA Cracks Down on Violators of Supplement Manufacturing Rules

In February and March 2011, the U.S. FDA posted Warning Letters sent, respectively, to a distributor of dietary supplements and a supplement manufacturer for violations of current Good Manufacturing (GMP) rules.

Recalls & Warnings

8/31/2006

Canada Advises Consumers Not To Use Adulterated Sleep Supplement

On August 30, 2006, Health Canada (the Candian Health Ministry) Health Canada advised consumers not to use Salt Spring Herbals Sleep Well Dietary Supplement because a sample analyzed by Health Canada has been found to contain the undeclared drug estazolam, a sedative that can be habit-forming when ...

Recalls & Warnings

6/26/2015

Seller of CoQ10, Anxiety Supplements and More Warned for Manufacturing Violations, Drug Claims

On June 6, 2015, the FDA issued a warning letter to Country Doctor Herbals, following a facility inspection which found the company's products, including  Herbal Flu Be-Gone, Herbal Multi-Bac, Herbal Nervine, Herbal Pain-A-Way, Herbal Pancreas, Herbal Parasite Cleanse, Herbal Perfect ...