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Clinical Update

7/18/2024

Overactive Bladder & Supplements

Find out if supplements are recommended for symptoms of overactive bladder (OAB) in our article about supplements for nighttime urination.

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Product Review

Cranberry Juices and Supplements Review

CL's Tests Show Which Cranberry Juices and Supplements Are Best and Cost the Least

CL Answer

10 Supplements That May Help Reduce Nighttime Urination (And 5 That May Not)

Waking up more than once during the night to use the bathroom? Learn more about the 9 supplements that may help and 5 others that don't.

A toilet in an empty bathroom at night

CL Answer

Does AZO Bladder Control really work for overactive bladder?

AZO Bladder Control information, including results from clinical studies on bladder control, dosage, and safety.

AZO

Clinical Update

4/25/2023

Nighttime Urination: Pumpkin Seed?

Can supplementing with pumpkin seed reduce the need to urinate at night among people with BPH (benign prostatic hyperplasia) or OAB (overactive bladder)? Get the details in the Pumpkin Seed section of our article about BPH. Also learn about other approaches in our article about supplements for nighttime urination.

Read more about Nighttime Urination: Pumpkin Seed?

Product Review

Glycine Supplements Review

Tests of Glycine Show High-Quality but Major Savings with Right Products.

Glycine Review 3

Product Review

Prostate Supplements Review (Saw Palmetto and Beta-Sitosterol)

Find the Best Prostate Supplement for Symptoms of BPH. See Which Prostate Supplement Passed or Failed CL's Tests of Quality.

Clinical Update

12/06/2020

Cranberry for Overactive Bladder?

Can cranberry supplements help with overactive bladder? See what a new study found in our article about Cranberry and Urinary Health.

Read more about Cranberry for Overactive Bladder?

Clinical Update

3/16/2019

Vitamin D for Overactive Bladder?

Vitamin D supplementation may help vitamin D-deficient people who suffer from urinary urgency or frequency. Get the details in the What It Does section of the Vitamin D Supplements Review. Also see our Top Picks for vitamin D supplements.

Read more about Vitamin D for Overactive Bladder?

Clinical Update

10/05/2021

Glycine for Urinary Frequency?

Can supplementation with the amino acid glycine improve symptoms of overactive bladder or reduce urinary frequency? See what a new study found in our updated answer to the question: Can glycine improve sleep or reduce nighttime urinary frequency?

Read more about Glycine for Urinary Frequency?

Clinical Update

10/26/2026

Could Cranberry Reduce Those Frequent Urges to Urinate?

Do cranberry supplements relieve overactive bladder symptoms? See how it performed and our Top Picks among cranberry juices and supplements.

Read more about Could Cranberry Reduce Those Frequent Urges to Urinate?

CL Answer

Does Prelief Help with Heartburn or Bladder Pain Caused By Acidic Foods?

Learn about Prelief, a product promoted to reduce acidity from foods and drinks that may cause bladder pain, frequent urination, heartburn, or indigestion. Discover what Prelief claims to do, the clinical evidence supporting its use, and important safety considerations.

Bottle of Prelief Caplets and Container of Prelief Powder

CL Answer

Can taking CoQ10 affect my thyroid levels or interact with my thyroid medication?

Learn more about CoQ10 and thyroid medications along with natural thyroid function. ConsumerLab.com's answer explains.

Elderly Woman Checking Thyroid Gland

CL Answer

Urinary Tract Infections (UTIs): Do Supplements Help?

Certain supplements may help reduce the risk of urinary tract infection (UTI) recurrence. Find out which might help and which might not.

Woman standing in bathroom holding her abdomen due to bladder pain caused by uti

CL Answer

Dimethyl sulfoxide (DMSO): Health Effects & Safety Concerns

Dimethyl sulfoxide (DMSO) is a colorless liquid promoted for osteoarthritis, interstitial cystitis, tennis elbow, rotator cuff tendonitis, wound healing, and many other conditions. Find out if it works and if it's safe.

Man applying DMSO gel to knee

Clinical Update

10/11/2022

Foods That Irritate the Bladder

In people with recurrent UTIs, be aware that several foods are known to cause bladder irritation. We've added this information to our Cranberry Review.

Read more about Foods That Irritate the Bladder

Clinical Update

11/04/2012

Vitamin D and Bladder Cancer

A new study looked at vitamin D levels and the risk of developing bladder cancer. Find out which levels were best, as well as which vitamin D supplements pass our tests, in the updated Vitamin D Supplements Review. More >>

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Clinical Update

10/23/2025

Prelief for Heartburn or Bladder Pain?

Does this product lead to less heartburn and bladder pain? See what the evidence says in our article about Prelief.

Read more about Prelief for Heartburn or Bladder Pain?

Clinical Update

3/01/2024

Sweeteners and Bladder Pain

If you suffer from bladder pain, find out which sweeteners have been associated with increased pain in our article about sugar substitutes. Also see our Top Picks among sugar substitutes.

Read more about Sweeteners and Bladder Pain

Clinical Update

5/30/2020

Cranberry for Cystitis in Men?

Cystitis (inflammation of the bladder) is common in men undergoing radiation therapy for prostate cancer. A study evaluated whether a cranberry supplement could reduce the incidence of cystitis in these men. Find out if it helped in our updated answer to the question: Are cranberry supplements helpful for men? Can they help with symptoms of prostatitis or urinary tract infections?

Read more about Cranberry for Cystitis in Men?

Clinical Update

6/18/2026

BPC-157 for Pain and Inflammation?

BPC-157 is getting attention for pain and inflammation, but does the evidence support the claims? See the current evidence for knee pain and bladder pain in our article about peptides, which includes information about TB-500.

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Clinical Update

6/12/2025

Saccharin & Cancer

Does saccharin cause cancer? A link between saccharin and bladder cancer has been debunked. Interestingly, preliminary research suggests saccharin may have anticancer effects. Get the details, and learn more about the pros and cons of saccharin in our article about sweeteners, which includes our Top Picks.

Read more about Saccharin & Cancer

Clinical Update

5/09/2023

Prostadine for Prostate & Urinary Health?

Prostadine is a supplement that claims to support prostate health and bladder control, but does it really work? Find out in our Prostate Supplements Review, which includes our Top Pick among prostate supplements.

Also see our article about  supplements to reduce nighttime urination.

Read more about Prostadine for Prostate & Urinary Health?

Clinical Update

10/20/2023

Vitamin E & Cancer Risk

Supplementing with vitamin E might increase the risk of recurrence of bladder cancer, according to a recent study. Get the details in the Cautions and Concerns section of our Vitamin E Supplements Review.

Read more about Vitamin E & Cancer Risk

Clinical Update

9/03/2024

Uqora / D-Mannose Caution

D-mannose is generally well tolerated, but be aware that an immune reaction was recently reported with the use of the popular D-mannose "bladder" supplement, Uqora. Get the details in the Concerns and Cautions section of our D-Mannose Supplements Review, which includes our Top Picks for D-mannose.

Read more about Uqora / D-Mannose Caution

News Release

April 24, 2025

ConsumerLab Tests Identify Best Glycine Supplements

White Plains, NY, April 24, 2025 —  Glycine supplements are promoted to improve sleep and mood, reduce symptoms of overactive bladder and chronic prostatitis, and for other benefits, but do they really work, and if so, which glycine products on the market are best?

Recalls & Warnings

October 30, 2025

“MyBladder” Bladder Control Supplement Recalled

On October 28, 2025, Purity Products recalled one lot of MyBladder, a supplement promoted to support bladder control, because company tests detected two strains of E. coli (Escherichia coli – strains O7:K1 and 1303) in the affected lot.

Recalls & Warnings

August 25, 2026

Thyroid Tablets Recalled

On August 21, 2026, Vitruvias Therapeutics, Inc. recalled one lot of Thyroid Tablets, USP 30 mg because testing confirmed the product may be superpotent (i.e., may contain a higher dose than indicated on the label).

Recalls & Warnings

July 12, 2013

Herbal Supplement Company Warned For Drug Claims, Manufacturing Violations

On June 18, 2013, the FDA issued a warning letter to Herbs of Light, Inc.

Recalls & Warnings

April 01, 2017

Maker of Prelief, Urinozinc Prostate Health Formula Warned for Manufacturing Violations

On March 16, 2017 the FDA issued a warning letter to DSE Healthcare Solutions, LLC, following a facility inspection which found the company's products, including Prelief and Urinozinc Prostate Health Formula to be adulterated because they were prepared, packed, or held under ...

Recalls & Warnings

January 11, 2012

Herbal Extract Company Warned by FDA of Making Drug Claims

On January 3, 2012, the U.S. FDA sent a Warning Letter to Herbal Extract Plus, LLC regarding legal violations for claiming its herbal products can cure or prevent diseases.

Recalls & Warnings

August 26, 2014

Maker of Herbal Supplements Warned for Manufacturing Violations and Drug Claims

On August 8, 2014, the FDA issued a warning letter to EnerHealth Botanicals, LLC following a facility inspection which found the company's products, including Parasite Purge Herbal Remedy, Black Walnut Extract, Bladder Cleanse Herbal Extract, Lung Renewal Herbal Remedy, EchinOsha and Daily Immune ...

Recalls & Warnings

April 16, 2014

Seller of Aloe, Thyroid and Other Supplements Warned for Manufacturing Violations and Drug Claims

On March 21, 2014, the FDA issued a warning letter to Aloe Man International Corp.