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Product Review

Collagen Supplements Review

See our Top Picks for Wrinkles and Joints

CL Answer

Are Peptides Such as BPC-157 and TB-500 Safe and Effective?

Find out about BPC-157 and TB-500, including what they're promoted for and if they're safe.

White capsules vials and a syringe on a blue background

Product Review

Bone Broth Review

Find the Best Bone Broth for Quality, Taste, and Value. Four of 10 Products Fail to Get CL Approval.

Bone Broth Review 2025

CL Answer

Are there side effects from collagen supplements?

Find out if there are collagen side effects from supplements (collagen hydrolysate, collagen peptides, etc.) such as nausea, constipation, skin rash and others. ConsumerLab.com's answer explains.

Collagen Supplement Side Effects -- woman with stomach pain

CL Answer

Does collagen taken as a supplement help with arthritis? I'm seeing it in products for joint health.

Learn more about collagen supplements, including evidence from clinical studies on arthritis and muscle strength and safety.

Collagen Supplements for Joint Pain

Product Review

Lion's Mane and Chaga Supplements Review

Read Labels Carefully -- Many Can Mislead

Lion's Mane and Chaga Supplements tested by ConsumerLab.com

Clinical Update

10/15/2019

Collagen Peptides vs. Gelatin

It has been generally believed that amino acids are more bioavailable from hydrolyzed collagen (collagen peptides) than from gelatin (which is partially hydrolyzed collagen). A new study put this to the test. See what the researchers found in the What It Is section of the Collagen Supplements Review. Also see our Top Picks among collagen supplements.

Product Review

Protein Powders and Shakes Review

Find Out Which Protein Products Passed or Failed Our Tests

Protein Review 2026

Clinical Update

11/13/2025

TB-500 for Injury Recovery

Do supplements containing TB-500 help with injury recovery and are they safe? Find out in our article about BPC-157 and TB-500.

CL Answer

Conolidine: Evidence for Pain Relief, Safety, and CONOCB2™ Products Explained

Find out if conolidine, the main ingredient in CONOCB2 Blend, offers natural pain relief without the side effects of opioids. Also learn about the top conolidine products available today.

Three commercial products that contain conolidine

Recalls & Warnings

June 12, 2023

Vital Proteins Collagen Peptides 24 oz Recalled

On April 28, 2023, Vital Proteins issued a recall of a single batch of Vital Proteins Collagen Peptides -- Unflavored (24 oz) that were distributed to and sold by Costco. Canisters may contain broken blue pieces of plastic from a broken lid.

News Release

July 26, 2023

Best Collagen Supplements for Skin and Joints, According to ConsumerLab Tests

White Plains, New York, July 26, 2023 —  Collagen supplementation may modestly reduce wrinkles and the appearance of cellulite, and moderately decrease joint and tendon pain and improve flexibility in people with osteoarthritis.

News Release

October 04, 2019

ConsumerLab Tests Reveal Best Collagen Supplements for Wrinkles and Joints

White Plains, New York, October 4, 2019 — Collagen supplements are promoted to reduce wrinkles and decrease joint pain and stiffness, but do they really work, and if so, which products on the market provide the best quality collagen and the best value? To find out, ConsumerLab carefully ...

Product Review

L-Arginine Supplements Review

Choose the Best L-Arginine Supplement. Find Out Which L-Arginine Supplement Passed CL's Tests.

L-Arginine Supplements Reviewed by ConsumerLab.com

Product Review

Psyllium Fiber Supplements Review

Find the Best Psyllium Fiber Supplement and Avoid Lead.

Psyllium Review 2024

Clinical Update

9/26/2024

Collagen to Reduce Fatigue?

Did supplementing with collagen peptides reduce fatigue? Find out what a recent study showed in the Fatigue section of our Collagen Supplements Review, which includes our Top Picks for collagen.

Clinical Update

11/03/2023

Collagen For Bone Health?

Is there evidence that collagen peptides (as in Fortibone) strengthen bones? Find out in the bone health section of our Collagen Supplements Review. Also see our Top Picks for collagen for skin and joint health.

Also see: Do any supplements or diets help prevent or treat osteoporosis?

Clinical Update

2/01/2020

Collagen for Knees?

Collagen supplements have been tested in many studies to reduce pain and/or improve function in osteoarthritic knees. A recent study focused on collagen peptides. Find out if they worked (and see the results for other collagen products) in the Joint Pain section of the Collagen Supplements Review. Also see our Top Picks for collagen supplements for joint pain and for wrinkles.

Clinical Update

7/06/2019

Casein Peptides for Better Sleep?

People with difficulty sleeping were given a casein hydrolysate to see if it would help them sleep. Find out if it worked in the Casein section of the Protein Powders, Drinks and Shakes Review. Also see our Top Picks among casein and other protein products.

Product Review

Joint Health Supplements Review (Glucosamine, Chondroitin, MSM, Boswellia, Collagen and Turmeric)

18% of Joint Health Supplements Failed to Pass Our Tests. See Which Passed or Failed, and Our Top Picks.

Joint Health Supplements Review 2025

CL Answer

ConsumerLab’s Review of The 'Pause Nutrition Supplements by Dr. Mary Claire Haver – Are They Worth It?

Looking into The 'Pause Nutrition supplements by Dr. Mary Claire Haver? ConsumerLab examines the value of products like Omega-3 + Vitamin D3 & K2, Fiber GDX, Skin Boost Plus, and more. Find out if these supplements are worth the price and discover affordable alternatives.

The Pause

CL Answer

Best Supplements to Prevent Age-Related Muscle Loss

Discover the top supplements to prevent age-related muscle loss after 60. Learn how protein, fish oil, vitamin D, and more can help maintain muscle strength and combat sarcopenia.

Protein Review 2026

CL Answer

Supplements For Back Pain: What Helps, What's Hype

Some supplements may provide modest benefit for back pain, while others don't seem to work or haven't been evaluated for this use. Find out if supplements like collagen, devil's claw, PEA, pregnenolone, white willow bark, and others help.

Man holding lower back due to low back pain

Product Review

Probiotic Supplements Review (Including Pet Probiotics)

See What's Really in Probiotics and Our Top Picks

Probiotics 2025

CL Answer

Do any supplements or diets help prevent or treat osteoporosis?

If you have osteoporosis, you may be interested in supplements or diets for bone health. Find out which can increase bone strength and density.

Doctor discussing osteoporosis with older female patient

CL Answer

What are the health benefits of luteolin, and is it safe?

Find out if luteolin, a compound found in many fruits and vegetables, is beneficial for cancer, heart health, skin aging, age-related cognitive decline, and other conditions, and learn if it's safe.

Luteolin containing vegetables including celery peppers lettuce and spinach

CL Answer

What is Noopept? Can it really improve memory and cognition, and is it safe?

Learn more about Noopept, including results from clinical studies on cognition, safety, and dosage.

Memory Cognition Image for Noopept

CL Answer

Do hair loss supplements, such as Viviscal, Hair La Vie, and Nutrafol, or topical essential oils work?

Vitamins and supplements that may help with hair loss and thinning, including saw palmetto, beta-sitosterol, protein, iron, and vitamin D.

Supplements for Hair Loss -- woman looking at hairbrush

CL Answer

Do collagen or hyaluronic acid supplements really help aging or wrinkled skin?

Find out if collagen & hyaluronic acid supplements really help for aging or wrinkled skin and for skin care.

Collagen Supplements for Wrinkles? -- woman looking closely at her face in a mirror

CL Answer

Are there vitamins or supplements that can reduce my risk of breast cancer? Do any increase cancer risk?

Find out if certain vitamins, supplements and foods such as fish oil, olive oil, vitamin C and others, can help reduce the risk of breast cancer. ConsumerLab.com's answer explains.

Supplements & Breast Cancer Risk -- doctor holding pink breast cancer awareness ribbon

CL Answer

What is UC-II and does it help joints?

What is UC-II (undenatured type 2 collagen - InterHealth Nutraceuticals) and do clinical studies show that it works for joint health?

UC-II Collagen for Joint Pain? -- man with knee pain

Recalls & Warnings

June 22, 2023

FDA Warns Warrior Labz for Selling Products with Steroid-Like Substances and Prescription Drugs

On June 12, 2023, the FDA issued a warning letter to Warrior Labz SARMS following inspection of the company’s website and social media, which found that the company sold the following products labeled as containing steroid-like substances known as selective androgen receptor modulators ...

CL Answer

What are the best supplements for depression and anxiety?

Best natural supplements for depression and anxiety, including the evidence for fish oil, vitamin D, probiotics, and herbal supplements for depression such as curcumin (from turmeric) and saffron.

Best Supplements for Depression and Anxiety -- sad young woman sitting on couch, looking toward the window

CL Answer

Do any supplements help prevent or improve cataracts?

Find out which supplements may help with cataracts, including selenium and vitamins A, B1, B3, C, and E.

Doctor Shining Light for Patient Eye Exam

Clinical Update

2/24/2013

Calcium Risk for Women

A long-term study found that women with high calcium intakes from their diets were 40% more likely to die during the study than women with moderate calcium intake. Worse, the risk of death was 157% higher for women with high dietary calcium intake who also took a calcium supplement. What should you do? Get the details in the recent update to the Calcium Supplements Review and read our latest recommendations on calcium intake in the What You Need to Know section.)

Recalls & Warnings

April 30, 2021

FDA Warns Seller of Fish Oil, Apple Cider Vinegar, Collagen, and Elderberry Supplements

On April 13, 2021, the FDA issued a warning letter to Orphic Nutrition following a review of the company's websites, which found statements made about the products Apple Cider Vinegar Capsules, Ashwagandha Capsules, Garcinia Cambogia Capsules, Premium Collagen Peptides Capsules, Elderberry ...

Recalls & Warnings

June 16, 2019

"Immune Support" Throat Sprays Recalled

On June 13 2019, APS BioGroup, Inc. issued a recall of four "immune support" throat sprays because they have the potential to be contaminated with Stenotrophomonas maltophilia, a bacteria that can cause respiratory infection, particularly in individuals with weakened immune systems.

Recalls & Warnings

July 13, 2023

1st phorm Level-1 Protein Supplements Recalled Due to Staph Risk

On June 21, 2023, International Food Companies DBA International Food Products recalled two protein supplements due to potential contamination with Staphylococcus aureus.

Recalls & Warnings

January 10, 2024

Spring Valley Biotin & Collagen Liquid Recalled Due to Mold

On December 1, 2023, BioMylz Pvt. Ltd. issued a recall of 24,324 units of Spring Valley Biotin & Collagen Liquid Natural Berry Flavor products due to potential mold contamination. BioMylz is the contract manufacturer for the Spring Valley product, which is a Walmart-owned brand.

Recalls & Warnings

October 19, 2023

Jay Robb Protein Powder Recalled

On October 13, 2023, Select Custom Solutions recalled one lot of Jay Robb Vanilla Flavored Egg White Protein 24 oz because the product may contain hard, plastic, foreign material which could pose a choking hazard. No adverse events have been reported to date.

Recalls & Warnings

November 29, 2019

FDA Warns Seller of "All Natural" Treatment for Opioid Withdrawal, Migraines & More

On November 18, 2019, the FDA issued a warning letter to EPH Technologies, Inc., following a review of the company's websites, which found statements made about some of the company's products, including Detoxoplex, Sinople, and Migrenz, to be drug claims.

Recalls & Warnings

June 13, 2024

Suntegrity Tinted Sunscreen Lotion Recalled Due to Presence of Mold

On June 11, 2024, Suntegrity Skincare issued a recall of nine lots of Suntegrity Impeccable Skin Sunscreen Foundation (Multiple Shades) after discovering that certain products had higher than acceptable levels of mold, specifically the Aspergillus Sydowii species, which can cause ...

Recalls & Warnings

April 16, 2012

Protein Supplement Maker Fails FDA Audit -- Many Products Affected

The FDA sent a Warning Letter (dated April 2, 2012) to Theta Brothers Sports Nutrition, Inc. regarding numerous violations of good manufacturing practices at its Lakewood, New Jersey facility.