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Collagen Supplements for Wrinkles? -- woman looking closely at her face in a mirror


Adults lose about 1% of the collagen in their skin each year, which contributes to thinning and wrinkling in aging skin. This loss of collagen may be more evident at an earlier age in women, who have lower collagen density in their skin than men. Hyaluronic acid (also called hyaluronan) is another component of skin that decreases with age. Many supplements containing collagen and/or hyaluronic acid, such as, NeoCell Derma Matrix Collagen Skin Complex, Life Extension Hair, Skin and Nails Rejuvenation Formula, Lindberg Skin Rejuvenator, and Natural Factor's Hyabest® Hyaluronic Acid, are promoted to improve the skin and some contain branded collagen ingredients such as VERISOL and BioCell Collagen or Hyabest Hyaluronic Acid, which have been tested in studies.

But can taking collagen and/or hyaluronic acid supplements, in the form of capsules, tablets, or powders, actually increase the collagen in skin, or improve the skin's appearance? The evidence suggests that some products may have modest effects, but the evidence for other products is weak. For details, see the Aging Skin and Wrinkles section of the Collagen Supplements Review, which includes our Top Picks for collagen supplements for skin.

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December 15, 2019

I’ve had a gastric sleeve and have been told to get 60 to 80 g of protein a day. I use Unjury shakes (2 a day, 20 g each) because I have limited stomach capacity.

If I wanted to add collagen to my daily intake for improving my skin elasticity and time help my knee pain, what would you advise and can I count the collagen toward my protein requirement?
December 16, 2019

Hi Catten - Yes, collagen is almost entirely protein and taking it as a supplement would, therefore, contribute to your protein intake.

September 15, 2019

"Note: ConsumerLab is currently testing collagen supplements and will issue a report covering popular products in the fall of 2019."

And these test results are much anticipated and greatly appreciated. I, myself, am currently taking a "hydrolyzed collagen powder," which purportedly has 18 amino acids (8 essential). It supposedly aides in promoting muscle and ligament repair, flexibility, and recovery. Asking rhetorically, does it REALLY do everything it promises to do, or am I simply wasting my money. Thanks, again.

September 8, 2019

Hydrolyzed collagen is available in the United States. It is called Great Lakes Gelatin. 100% hydrolyzed collagen powder. Non GMO, no fillers, grass fed bovine, glyphosate free. I have been purchasing it for at least two years.

June 25, 2021

Me too! Love it!

July 2, 2021

Thanks for recommendation

September 4, 2019

I'm more interested in the joint support benefits. What's the scoop on that?
September 4, 2019

Hi R.S. - Please see our CL Answer about collagen for arthritis and joint pain

July 18, 2019

Can you please do testing on currant collagen supplements, there are so many available and would like to know which one's are approved... Thank you

July 8, 2019

Could you also review some marine, chicken and eggshell membrane collagen products that offer up other types of collagen! I am using just beef hydrolyzed currently and just in a few weeks have seen a significant improvement in my psoriasis

renee 18296
September 4, 2019

What brand are you taking and how much? I'd like to give that a try. :)

May 1, 2019

can you please review Clean Sourced Collagens with your collagen study? Thanks
May 13, 2019

Thank you for your suggestion John, we will keep it in mind.

March 12, 2019

What does porcine-derived mean in your collagen article?
March 18, 2019

Hi Alma - Porcine-derived means that it is sourced from pigs. We've added a note in the answer to clarify.

January 28, 2019

I just tried a collagen powder with verisol (Whole Foods Market, Collagen (Verisol) Powder) for the first time and broke out into a rash. I have never had any food allergies, so I was rather surprised by this. My question(s) Does CL know of research showing 1) how common a reaction this might be and 2) does it make sense to try a different brand or should I assume the reaction is to the verisol itself?
February 11, 2019

Hi Margy - Thank you for sharing your experience with this. Although it does not appear to be common, there have been reports of skin rash associated with the use of collagen supplements. We've added information about this to the "Safety and side effects" section in the Answer above, and published a CL Answer about collagen side effects:

March 10, 2019

Major headaches for me.

October 9, 2018

I am 57 years old.I started using Youtherapy Collagen a few years ago for my stomach problems. I had read that collagen helps with leaky gut and gastritis. After a couple of weeks I found that not only did it help with my stomach, I also realized that I no longer had the arthritic pain in my hands anymore. I also wasnt achy or sore after doing physical work. I was so surprised as I never expected that it would help with the arthritic pain. I havent used it in a while as its hard to swallow 3 of those large pills twice a day. As expected my hands hurt all over again. Does anyone recommend collagen supplement that isnt such a hassle to take?

October 17, 2018

Just take powder

October 9, 2018

What is the email address to send questions to? I can't find one.

My Question:

How can I find out which collagen supplements contain VERISOL? I read your article about Collagen with Verisol but couldn't find any suggestions as to what to buy.

Searching VERISOL in the Search bar showed nothing too.
October 9, 2018

Hi Nicole - There are a number of collagen products on the market that contain VERISOL -- several are listed in the section that discusses the clinical evidence for treating aging skin in the answer above (

Questions pertaining to a particular CL Answer can be submitted in the comments section for that Answer, and questions about other products or topics can be submitted to the email address listed at the bottom of each CL Answer (

December 1, 2018

I just searched from Google for Verisol powder to by and got over 15 products and sites to buy it from.

February 6, 2019

I have been using a Verisol collagen product called by Besha, Inc. - its awesome and affordable. Two teaspoons a day, 35 servings per jar of powder and its only $17.99.

March 4, 2019

Thank you Donna!

June 24, 2019

is this safe if one is on xarelto? I would simply like to know if collagen thins the blood. If it does not, then I can use a collagen supplement.

November 1, 2017

I think good quality collagen powder, in general, is very useful and many have witnessed beneficial results, including myself. I think as with everything striving to find it sourced from grass-fed AGA certified, a non-GMO fed stock is an excellent idea yet hard to find/verify. If a person "can" they are probably better off making their own stock from said animals to take in collagen but if not I think you can get what you need more easily from powders which would yeild quite a few pills. You may be interested in researching to hear what past employees said ( on Googles "GlassDoors") about the integrity of Vital Proteins Co. which wasn't very good.

October 30, 2018

thank you for the tip re vital proteins

December 27, 2018

Where did you find it....or what was the general consensus on Vital Proteins?

October 29, 2017

I am 71 and have been taking hydrolyzed collagen for about a year. It is one of the best supplements ever. I had hip replacement, have some arthritis and this is like magic In Keeping me pain free. Also great for skin hydration. No longer need to cream my body each day.

October 7, 2018

Hello Ruth16088, what brand are you using and what dosage are you taking? I like your comment about Hydrolyzed collagen. I would like to try it too! You must feel fantastic :)

J. M.17234
October 10, 2018

Ruth, I, too, would like to know what collagen you are taking for your good results.
Please let us know. Thx, Judith

September 12, 2019

I also am interested in learning about the product that you used. Please don’t keep us in suspense!??

May 8, 2017

I have been taking collagen powder from Vital Proteins since March and find it to be very helpful in reducing my low back pain. (I had a compression fracture 5 years ago). The pain was daily and debilitating after being on my feet for four hours. I am 76 yeas old and very active.

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