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Collagen Supplements for Joint Pain


Collagen hydrolysate (enzymatically hydrolyzed collagen or collagen peptide) may help reduce the pain of osteoarthritis (worn joints) according to some preliminary studies. There is also evidence that a branded collagen that has not been hydrolyzed, UC-II, may be helpful.

For details, see the Joint Pain section of the Collagen Supplements Review, which includes our tests of products containing UC-II and other collagen ingredients, and our Top Picks for collagen supplements for joints.

For information about other supplements used for joint health, see the Glucosamine, Chondroitin, MSM and Boswellia Supplements Review >>

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September 6, 2019

I am age 78. Up until I reached my 70’s, I did not have symptoms of osteoarthritis or of congestive heart failure,and
felt grateful; however, that changed in last 5 years. I developed severe knee-joint problems and started going for injections of hylauronic acid/collagen every 6 months. These have relieved the pain for close to 5 months. The knee pain led to my walking with limp, leading to low-back pain. Once injections (need to get in both knees 1X week for 3 weeks in a row).
Once completed 3 weeks of injections all pain is gone in knees/back. So 2X per year works very well for pain relief, and I can resume walking again. Injections are not painful. Dr. advised only other way would be to have surgery & knee-joint replacements, and, at my age, don’t want to risk, plus recovery after surgery would be lengthy at my age. I read all your comments and hope this is helpful to you. If I were in mid-years would have joint replacement surgery; just a thought for younger fellow sufferers....replacements last a minimum of 10 years I was told. Hope this helps and will pray for you all.

July 7, 2019

I'm so glad to read there will be a report on collagen later this year :D I tried 3 different brand of collagen peptides. Vital Proteins gave me the worse stomach pain. I'm lactose intolerant and I have a feeling the product contains dairy, even when they claimed it doesn't. Then. I tried Sport Research and made me bloated all the time. Finally, I tried Further Food. I was skeptical to give it a try because I was convinced collagen peptides wasn't for me. I started with a little big at a time for 2 days then I took the full scoop. Thank God this product is working for me. After almost 3 months my knee pain improved 90%, my nails are healthier and my hair is growing a lot, just length not thicker. My skin is really soft. This collagen is really good for my leaky gut. I would like to read a review by CL on Collagen Peptides including the one I'm taking. My husband have been taking the first 2 collagen that I mentioned and it's working good for him, less joint pains and his skin is beautiful.

October 1, 2018

I have been taking ProCaps Marine Collagen Peptides for a month , which contains 5g protein , 5g Marine Collagen Peptides, 500mg msm . I have noticed slight improvement in joint relief , hair condition .I haven't noticed a skin changes yet maybe it will take more time.

March 18, 2018

comment: I read that most of the supplements you mention relief pain. But I am interested in Healing. Pain relief is the wrong Messenger!
I am a hard-working healthy 80 years old and my experience is that use of some of the supplement ingrédients you mention here may indeed help. But nothing beats regular and varied forms of motion and eating naturally.
For somebody raised 50-60 years ago in engineering and theoretical physics the studies you and others mostly refers to are quite unconvincing: mice may be genetically similar to us, but we are not mice.
Studies reporting on pain relief are quite misleading. Not only becausse of tis subjectivity, but also the cloud of other factors influencing this kind of sensation make pain a quite unreliable indicator. For most 'pains in your back', for instance, there are no physiccal indications.
March 19, 2018

Hi Gjalt - We agree that supplements are not a replacement for a healthy diet and exercise, although in some situations supplementation with certain nutrients is recommended (see Also, while we do refer to one study of collagen absorption in mice in the Answer above, the studies we cite regarding efficacy of collagen in arthritis are clinical trials in people.

April 7, 2019

When will you be testing collagen supplements?
April 8, 2019

Yes, as noted in the answer above. We expect to publish a report on collagen supplements later this year.

May 1, 2019

Thanks for including collagen in your lineup. I look forward to seeing it
May 1, 2019

Thank you Jane! Be sure to check the ConsumerLab newsletter as the results will be announced in the newsletter when they are published.

May 5, 2019

Please test and do a report on Andrew Lessman Marine Collagen Peptides.

Thank you.
May 9, 2019

Thank you for your suggestion Barbara.

July 7, 2019

Can you also test Great Lakes Gelatin Collagen Hydrolysate? I've been using this one and have had some nice benefits from it. Thanks! Love what you do here.
July 8, 2019

Hi Wendy - Thank you for your kind words, and your suggestion -- we will keep it in mind.

March 2, 2018

I just got over Collagenous Colitis. It was pretty horrible. Can taking collagen supplements create this problem? I've been taking them for years and stopped after this diagnosis.
March 16, 2018

Hi KathyAnn - We are not aware of any studies or case reports linking collagen supplement use to collagenous colitis (although as noted in the answer above, mild gastrointestinal symptoms have occasionally been reported). Researchers are not sure what causes collagenous colitis; some suspect it may be an autoimmune condition, and there is some preliminary/mixed evidence it can be triggered by use of certain medications, such as NSAIDs (;

ferdinand 16387
January 30, 2018

Has really reduced my knee pain along with water exercise. I have no knee pain at night and i am able to walk fairly well most of the day . It took a couple of months to start noticing the good effect. Using for 2 years + and still feel that there is still modest improvements occurring.

October 16, 2016

Make your own Bone Broth from organically & pasture-raised animals. It's easy to make. Or, order it from Dr. Kellyanne Petrucci's website. I have no affiliation with this, just a satisfied customer. Her book has great healthy recipes. It's the only way to get Organic that I know... and making your own is a way to obtain collagen/gelatin & marrow that is Organic and fresh. Even though I was a vegetarian for a very long time, adding homemade bone broth to soups, stews, sauces, my diet was medicinal and worth the change. It really is easy to make-honestly! Just follow one of Dr. Petrucci's many recipes. I definitely prefer making it fresh over a supplement ??

November 29, 2015

Does one need to take collagen in liquid form for the benefits mentioned here? Any evidence that taking it by capsule produces similar relief? Thx, Suzanne

October 31, 2017

I would think you would have to consume a lot of capsules to get the quantity needed making it much easier to take from the powder form in water. The ones I have tried are all tasteless and mix well with many beverages other than just water. Even works in coffee.

May 1, 2019

Hi Andrew
You didn’t mention a brand. Can you share please? I also take collagen but I find the flavor too offensive to take just in water. I use Garden of Life grass fed collagen, unflavored, which has 20 g of collagen peptides per serving -- A great product but I have to put it in apple juice which then adds sugar to my diet

May 1, 2019

Can you put it in coffee?
May 13, 2019

Hi Lisa - This would depend on the type of collagen because, collagen can denature (breakdown) with heat. Probably best to let the coffee cool at least a little before adding collagen.

July 18, 2019

Nordic Naturals collagen has a pleasant strawberry taste, dissolves easily in liquid. Would you be testing them this year? I really like their products for quality and efficacy

September 14, 2015

Is there any type of plan collagen that can substitute for the bovine or other animal type of hydrolized collagen?

November 16, 2015

Hi Robert - Some supplements are labeled as containing "marine collagen," typically derived from fish -- but we are not aware of any plant-derived collagen products.

May 5, 2017

The UC-II type undenatured collagen is from chicken

October 25, 2017

I use a fish-derived collagen from Elavonne - you can get it on Amazon. I think it's a great product. The bovine collagen is much cheaper, but it made me break out really bad - don't know why.

February 2, 2020

I am willing to try the type ll collagen but am wary of chicken unless it comes from an organic source.

September 14, 2015

I have a fear of getting spongiform encelapathy, or MAD COW's disease from cows because I saw a warning of it.

I don't like vitamins or medications that are obtained from animals or sea creatures, even though my medication caplets may have it in it.

I'm thinking that the processing should kill any virus that is in the products, however its scary to think about.

September 18, 2015

Same here. I don't think during the process it is heated that much or else it would be denatured. The best way to stay away from that is to look at the country of origin. Some country are safer than other. Can consumer lab comment on this?

April 29, 2015

Marilyn 43
I would like to find collagen hydrolysate certified as organic. Does anyone know of any?

September 13, 2015

Great Lakes Hydrolyatsate Collagen is recommended by my nutritionist. She believes in doing organic when possible so I don't think there is an organic collogen on the market yet or she would have recommended it...its non GMO, GF. I'm taking it to heal leaky gut. This form of collogen is suppose to be easily absorbed by the body.
Hope that helps.

October 16, 2016

Make your own Bone Broth from organically & pasture-raised animals. It's easy to make. Or, order it from Dr. Kellyanne Petrucci's website. I have no affiliation with this, just a satisfied customer. Her book has great healthy recipes. It's the only way to get Organic that I know... and making your own is a way to obtain collagen/gelatin & marrow that is Organic and fresh. Even though I was a vegetarian for a very long time, adding homemade bone broth to soups, stews, sauces, my diet was medicinal and worth the change. It really is easy to make-honestly! Just follow one of Dr. Petrucci's many recipes. I definitely prefer making it fresh over a supplement ??

February 10, 2019

I don't know about organic, but I just bought ForefrontHealth Collagen Protein Hydrolysate that is from grass-fed, pasture raised animals. I just tried it for the first time in my morning smoothie, and was disappointed that it didn't completely dissolve -- it was gritty.

August 18, 2014

I have been taking collagen supplements since my early 40s, first in the form of gelatin and than as hydrolyzed collagen. I began taking it because I had creaky knees after jogging along with some shin splints and accompanying pain. The noisy knees and shin splints went away. I am now in my 60s and my hair, skin, and nails appear in good shape and I look and feel in much better shape than my peers. I am still able to get up and down off the floor with no trouble. My joints feel good and I would recommend the supplement to anyone over 30. I use a powdered form (Nutrajoint from Knox) and take a scoop a day which provides about 10 grams of hydrolyzed collagen. Since it also has calcium in a form that is easily digested, it's definitely a win-win for supplements

anthony 83
August 4, 2014

I'm 73 years old. I have been taking hydrolyzed collagen regularly for years (about 6.6 grams per day. Many years ago my podiatrist prescribed it for bursitis pain in one of my feet. The pain practically immobilized me. The pain is long gone but I continue to take it. Some of the benefits may be no joint pains, less than typical facial aging or wrinkles minimum loss of head hair (baldness is typical with most of the men in my family).

September 14, 2015

What brand do u take

anthony 7968
September 23, 2015

Great Lakes Hydrolyatsate Collagen

October 7, 2015

Agree completely! I recommend it to my nutrition clients and take it myself.

Be aware that there are three different colored cans. The green can doesn't gel up in liquids, the red can does. The orange can is Kosher, but Im not sure if it gels or not.

The Great Lakes website should have the answer.

Teresa 8178
December 11, 2015

Does it help with stiffness? My husband (68) and I (66) are both very stiff so I would really like something that would help with that. We are both very active and would like to be able to get up and down easier. Comments please!!

March 13, 2017

I add Great Lakes every day to my coffee along with coconut oil!

September 4, 2017

I also just started taking Great Lakes Hydrolyatsate for my joints. I take two TBS each morning with water or juice. I use the green can because it mixes easily. Based on the research, I do not expect any immediate results but hope to see some in 6-8 months. I plan to take it long term.

February 10, 2019

A am taking Great Lakes Collagen for repair of my hip after a fall. I was diagnosed and they recommended hip replacement surgery but I can't due to having an issue with illius. The collagen is helping re establish good hair and nails while rebuilding the hip cartilage I lost. I would recommend this product, but it takes time, so don't expect overnight miracles.

Could heel spurs be a side effect of taking the collagen or of the Psoriatic arthritis I have developed since my fall?

February 10, 2019

Are you taking a good quality fish oil or other oil product? As we age we need lubrication and that may help. I am hopeful collagen will help my stiffness over time, but have lots to fix before the stiffness disappears. Good luck with it.
February 14, 2019

Hi Carol - You can find information about the evidence for fish oil for rheumatoid arthritis and osteoarthritis in the "Arthritis and Inflammatory Diseases" section of the Fish Oil Supplements Review:
February 15, 2019

Hi Carol - We aren't aware of any reports of heel spurs associated with collagen supplementation, but they can be related to psoriatic arthritis

J Naomi17871
May 25, 2019


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