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Our Members Asked:
Do "Mr. Happy Stack" supplements improve memory, cognition and mood, and are they safe?
Reviewed and edited by Tod Cooperman, M.D.
Answer:
Supplements such as Happy Stack (Pure Nootropics), The Brain Booster Stack (from Vitamonk LLC) and similar "stacks" contain combinations of "nootropic" ingredients that supposedly enhance memory, cognitive function, and/or mood. The combinations vary, but typically include uridine (as uridine 5'monophosphate) and choline (as alpha-GPC) and may include other ingredients, such as docosahexaenoic acid (DHA), an omega-3 fatty acid.To help answer the question of whether or these supplements work, we investigated the evidence behind these products and their ingredients, including potential side effects and drug interactions. Sign in for our review and conclusions.
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Related CL Answers (6)
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Jerry 20512
August 5, 2020So, are there 'any' supplements that can improve, or delay, dementia & alzheimer?
ConsumerLab.com
August 9, 2020Please see our CL Answer about supplements for memory and cognition https://www.consumerlab.com/answers/do-any-supplements-help-with-brain-function/supplements-for-memory/.
Nate20510
August 5, 2020I read about the Mr. Happy stack several years ago in a forum where a man ("Mr. Happy" was his profile name?) had a long list of research sources and instructions for how to take it.
I don't see that the testing listed above followed the correct process of slowly increasing DHA levels and Uridine for several weeks, then adding in Alpha-GPC slowly.
Caffeine needs to be nearly eliminated from this process too because you will go crazy if you continue a coffee/caffeine habit; the energy levels will be too much.
I tried this stack several years ago and feel like I regenerated my dopamine system. I woke up in the morning without any grogginess and jumped out of bed, found myself laughing at random things again, and felt there was color back in my life.
I continue to take Uridine and fish oil, but became afraid of the Alpha-GPC and CDP-Choline as they were hard for me to get the right amount without getting so much brain energy I felt like I couldn't calm down.
I wanted to drink caffeine in the morning still too, which is petty but true.
ConsumerLab.com
August 17, 2020Thank you for sharing your experience, although we are not aware of clinical evidence showing an added benefit from taking DHA and uridine for several weeks before taking alpha-GPC.