Our Members Asked:
Do face creams, anti-aging serums, and acne gel treatments containing vitamin A or retinol reduce bone density or increase the risk of fractures?
Vitamin A derivatives, or retinoids, such as retinol, retinyl-palmitate, retinyl-acetate and retinaldehyde are common ingredients in anti-aging creams and serums that promise to improve skin tone and dimmish fine lines and wrinkles. These derivatives are also found in over-the-counter acne treatments such as Differin gel (which contains adapalene, a synthetic form of retinyl-palmitate). There is evidence that topical retinoids have antibacterial, anti-inflammatory and antioxidant effects, and may also promote the synthesis, and slow the breakdown of collagen — all of which may improve the appearance of the skin.
Although there have been concerns that high oral doses of retinol may reduce bone mineral density and increase the risk of fractures, not all studies have found an increased risk, and there does not appear to be increased risk associated with topical retinoid products.
However, topical retinoids can cause other side effects, such as redness, scaling, dryness, and stinging/burning, and there are ways to minimize these occurrences. There have also been reports linking topical retinoid use and birth defects.
More details are in the Topical creams, gels, and serums section of our Vitamin A Supplements Review.
Join today to unlock all member benefits including full access to all CL Answers and over 1,300 reviews.Join Now
Already a member? Sign In Here.
Join now at www.consumerlab.com/join/
Submit your comment
This feature is restricted to active members.
Join now to add comments and get all member benefits, including over 1,300 reviews.Join Now
Already a member? Sign in here.
Agree to Comment Terms
Please abide by the following:
For your privacy, only your first name (from your account) followed by a random number will appear with your comment. Your last name and email address will not be displayed.
Your comment has been submitted
We will review your comment before it is posted.