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Lion's Mane and Chaga Mushroom Supplements

Lion's Mane and Chaga Supplements tested by ConsumerLab.com

Our Review gives you our Top Picks for the best lion's mane and chaga supplements and food products. See which brands passed our tests and learn more about uses, side effects, risks, health benefits, cost, and quality.

Lion's Mane and Chaga Mushroom Supplements Review

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Clinical Update

12/27/2024

Lion's Mane Reformulated

Swanson Full Spectrum Lion's Mane Mushroom appears to have been reformulated, possibly in response to ConsumerLab's findings. Get the details in our Lion's Mane and Chaga Supplements Review, which includes our Top Picks for lion's mane and chaga and explains what to look for on labels to avoid being misled.

CL Answer

What supplements should I stop taking before surgery?

Info on which supplements to avoid before surgery due to increased risk of bleeding or interference with anesthesia.

Supplements to stop before surgery - operating room

Product Review

B Vitamin Supplements Review (B Complexes, B6, B12, Biotin, Folate, Niacin, Riboflavin & More)

See Our Top Picks and Which 5 Failed Testing

B Vitamins Review 2024

Clinical Update

6/27/2025

Is Mushroom Coffee Healthier?

Mushroom coffee is promoted as healthier than regular coffee, but does it really contain more nutrients? Find out in the What It Is section of our Lion's Mane and Chaga Supplements Review, which includes our Top Picks for lion’s mane and chaga, as well as reviews of MUD/WTR and Four Sigmatic Instant Coffee Mix.

Product Review

Reishi Mushroom Supplements Review

Find the Best Reishi Mushroom Supplement. See How Reishi Supplements Differ.

Reishi Mushrooms tested by ConsumerLab.com

CL Answer

Does ergothioneine help prevent age-related problems such as impaired cognition, Alzheimer’s disease, Parkinson’s disease or cataract, and is it safe?

Learn about ergothioneine and its potential use for cognitive impairment, dementia, Alzheimer's disease, Parkinson's disease, cataract, or kidney disease, as well as its safety and cost of supplements containing this ingredient.

Various types of mushrooms that contain ergothioneine in a wooden bowl on a wooden countertop

Clinical Update

10/24/2024

Avoiding Counterfeit Mushrooms

A mushroom supplement maker has won a lawsuit against a company allegedly selling counterfeit versions of its products, including on Amazon. Details are in our article: Where to Safely Buy Real Vitamins and Supplements Online.

For ConsumerLab’s test results for mushroom supplements, see our Reishi Mushroom Supplements Review and our Lion's Mane and Chaga Supplements Review.

Clinical Update

12/09/2022

Mushroom Supplement Interaction

Can mushroom supplements interfere with tests for fungal infections? Find out in the Concerns and Cautions section of the Lion's Mane and Chaga Supplements Review as well as in our Reishi Supplements Review.

CL Answer

What are the health effects of turkey tail mushroom and is it safe?

Learn about the possible health effects of turkey tail mushroom, including its use as adjuvant treatment for cancer and for boosting immune function, plus get information about possible side effects and find out why ConsumerLab has not yet tested turkey tail products.

Turkey tail mushrooms growing on the side of a tree

Clinical Update

5/05/2023

Counterfeit Supplements

Counterfeit versions of psyllium, a multivitamin, magnesium, and eight other types of supplements from a major brand have been sold online. Details and how to avoid this are in our Psyllium Supplements Review.

A popular brand of mushroom supplements has also reported counterfeit versions of its products. Details and how to avoid this are in our Lion's Mane Review.

Clinical Update

2/14/2023

Does Lion's Mane Boost Cognition?

Did taking lion’s mane boost cognitive function in healthy, young people in a recent study? Find out in our Lion's Mane Review, which also discusses lion’s mane’s effects on older people and identifies our Top Pick among Lion's Mane supplements.

Also, see our article about other supplements for brain function.

CL Answer

With herbal supplements, what is the difference between root powder and root extract? Does it matter?

Learn more about the different forms of herbal supplements, including aloe, boswellia, ginkgo, green tea, and milk thistle.

Herbal Supplements

Clinical Update

12/23/2023

Lion’s Mane for Cognition?

Did taking lion’s mane before a cognitive test improve results? Find out what a recent study showed in the Cognitive function and memory section of our Lion’s Mane and Chaga Supplements Review, which includes our Top Picks among lion's mane supplements.

Also see: Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?

Clinical Update

4/17/2025

Lion’s Mane for Cognition?

Did taking lion’s mane improve cognition or mood in a recent study? Find out in the What It Does section of our Lion's Mane and Chaga Supplements Review, which includes our Top Pick for lion’s mane.

Also see: Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?

Clinical Update

8/26/2022

Lion's Mane for Depression, Anxiety, Gut Health

Does lion's mane (promoted for memory) help with depression, anxiety or gut health? See our article about lion's mane.

Clinical Update

6/17/2022

Lion’s Mane for Neuropathy?

Does supplementation with lion’s mane reduce symptoms of neuropathy? Find out what evidence suggests in our article about lion’s mane.

Also see our CL Answer about supplements for nerve pain.

Clinical Update

4/21/2025

Something to Watch Out for With Chaga

If you are looking to purchase a chaga supplement, you may want to avoid a certain type of chaga, according to a recent study. For details, see the ConsumerTips section of our Lion's Mane and Chaga Supplements Review, which includes our Top Picks for chaga as well as for lion’s mane.

News Release

February 25, 2025

Top-rated Vitamin and Supplement Brands and Merchants for 2025 Based on Consumer Satisfaction

White Plains, New York, February 25, 2025 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on over 8,400 responses collected in November/December 2024.

Recalls & Warnings

June 18, 2025

Comvita Manuka Honey + Reishi and Lion's Mane Products Recalled

On May 23, 2025, Comvita USA INC recalled certain Comvita branded Manuka Honey + Reishi, Comvita branded Manuka Honey + Cordyceps for Energy, and Comvita branded Manuka Honey + Lion's Mane for Focus products due to a leaking induction seal on the packaging.

CL Answer

Is it safe to drink coffee regularly? Does drinking coffee increase or decrease the risk of cancer?

Learn more about coffee, its safety, if it's good for you, and if it impacts your risk of cancer.

Recalls & Warnings

January 04, 2024

Lone Star Botanicals Warned by FDA for Manufacturing Violations

On November 26, 2023, the FDA issued a Warning Letter to Lone Star Botanicals, Inc.

Recalls & Warnings

June 17, 2024

Do Not Consume Diamond Shruumz Products, Warns CDC and FDA

On June 12, 2024, the Center for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and America’s Poison Centers warned consumers not to buy or consume Diamond Shruumz chocolate bars, cones, and gummies.

Recalls & Warnings

September 24, 2024

Manufacturer of Mushroom Gummies Warned by FDA for Violations

On August 13, 2024, the FDA issued a Warning Letter to Restorative Botanicals, LLC, following an inspection of the company’s facility found the company’s products, including its My GUT Shrooms Gummies and My IMMUNE Shrooms Capsules, to be adulterated because they were prepared, ...

Recalls & Warnings

September 14, 2021

Seller of Lion's Mane, Other Mushroom Supplements Warned by FDA

On July 20, 2021, the FDA issued a warning letter to Brilliant Enterprises LLC because it found statements made on the company's website and social media about mushroom supplements, including Lion's Mane, BoomChaga, CordaCex, and LVL:MAX to be drug claims.

CL Answer

Does AHCC or active hexose correlated compound have anticancer or antiviral benefits, and is it safe?

Learn about AHCC and active hexose correlated compound, including whether these compounds are beneficial for liver, pancreatic, or prostate cancer, chemotherapy-related side effects, or the flu. Also, find out if AHCC or active hexose correlated compound are safe.

Capsules of AHCC in wooden spoon in front of green leaf

Recalls & Warnings

December 09, 2021

FDA Warns Seller of Curcumin, Lion's Mane, Quercetin & More

On November 9, 2021, the FDA issued a warning letter to Synaptent, LLC because it found statements on the company's website about its products, including Berberine HCL, Curcumin, Lion's Man, Milk Thistle, Quercetin, Boswellia Serrata Extract, and Garlic Extract to be ...

Recalls & Warnings

July 17, 2023

Seller of Ashwagandha, Lion’s Mane & Other Supplements Warned for Manufacturing Violations

On March 17, 2023, the FDA issued a warning letter to Brand Packaging Group, Inc. after FDA inspection of the company’s facility found products to be adulterated because they were prepared, packed, or held under conditions that do not meet Current Good Manufacturing Practices (CGMP).

Recalls & Warnings

February 02, 2021

FDA Warns Seller of Reishi Mushroom Supplements

On January 6, 2021, the FDA issued a warning letter to Entia Biosciences, Inc following a review of the company's website, which found statements made about the company's products Lion's Mane - All Natural Supplement, Antrodia Mushroom Powder, Maitake Mushroom Powder, Reishi ...

News Release

February 26, 2024

Latest ConsumerLab Survey Shows Growth in Popularity of Magnesium and Several Smaller Supplements

White Plains, New York, February 26, 2024 — A recent survey of more than 10,000 people who regularly use dietary supplements shows that supplements that experienced the greatest absolute growth in popularity during 2023 were pregnenolone (+7.5 percentage points), magnesium (+4.8 pts), berberine (+4.

Clinical Update

10/12/2021

Mushrooms and Blood Sugar

Find out if supplementing with reishi or oyster mushrooms helps with blood sugar control. See what the latest research showed in our Reishi Mushroom Supplements Review.

Clinical Update

10/12/2021

Mushrooms and Gut Bacteria

Do mushroom powders have beneficial effects on gut bacteria? See what a preliminary study found in the What It Does section our Reishi Mushroom Supplements Review.

Clinical Update

4/19/2022

Shiitake Mushroom Rash

If not properly prepared, shiitake mushrooms can cause a distinctive skin rash, as noted in recent reports. The details are in our article about ergothioneine, a potentially beneficial compound found in shiitake and other mushrooms.

Clinical Update

6/21/2022

Muscle Weakness from Mushrooms?

Be aware that, although rare, mushrooms and mushroom supplements may trigger a rare autoimmune reaction resulting in muscle pain or weakness. Get the details in the Concerns and Cautions section of our Reishi Supplements Review.

Clinical Update

1/14/2022

Liver Injury With Reishi

Although very rare, liver injury has occurred in people taking reishi mushroom. Learn more, including details of a recent report, in the Concerns and Cautions section of our Reishi Mushroom Supplements Review.

Clinical Update

7/01/2022

Mushroom Compound for HPV?

Active hexose correlated complex (AHCC), produced from mushrooms, may help clear persistent, high-risk human papilloma virus (HPV) infection in women, according to a recent study. Get the details in the Antiviral Effects section of our CL Answer about AHCC.

Clinical Update

4/15/2022

Mushrooms for Lowering Cholesterol?

The beta-glucan in oats can help lower elevated levels of cholesterol, but can the beta-glucan in mushrooms do the same? Find out in our article about Supplements and Foods for Lowering Cholesterol.

Clinical Update

12/05/2023

Ergothioneine in Mushrooms

Ergothioneine, a potentially beneficial compound in mushrooms, was found to be reduced by certain types of food preparation. Get the details in our article about ergothioneine.

Clinical Update

12/09/2024

Vitamin D From Mushrooms?

Specially-grown mushrooms can be a good source of vitamin D, but a recent study showed that cooking may significantly decrease levels, as discussed in the Getting Vitamin D From Foods section of our Vitamin D Supplements Review.

Also learn about getting vitamin D from other foods, and see our Top Picks among vitamin D supplements.

Recalls & Warnings

December 15, 2020

Mushroom Supplement Seller Warned for Drug Claims

On December 4, 2020, the FDA issued a warning letter to Desert Alchemist LLC following a review of the company's website, social media, and Etsy.com store (www.etsy.

Recalls & Warnings

February 06, 2023

FDA Warns Companies Promoting Products to Treat Monkeypox, COVID-19, & Other Viruses

On January 30, 2023, the FDA issued a warning letter to four companies following review of the company websites, which found statements about company products to be drug claims because they were promoted to mitigate, prevent, treat, diagnose, or cure viruses such as monkeypox.

Clinical Update

11/21/2023

Vinegar or Baking Soda for Washing Produce?

Is vinegar or baking soda more effective than water for cleaning fruits and vegetables? See what research suggests in our article about fruit and veggie washes.

Also see which method experts recommend for cleaning mushrooms.

Clinical Update

10/28/2024

Concern with Cordyceps

If you use the mushroom, cordyceps (Cordyceps sinensis), be aware of widespread cheapening with material that is not cordyceps. Learn what to look for on labels, in the Cordyceps section of our article about testosterone boosters.

Recalls & Warnings

July 19, 2023

FDA Warns Seller of Sleepy Time Products and Honey Herbal Syrups for Manufacturing Violations

On June 28, 2023, the FDA issued a warning letter to Eden’s Answers, Inc. after an inspection of the company’s facility found products to be adulterated because they were prepared, packed, or held under conditions that do not meet Current Good Manufacturing Practices (CGMP).

Recalls & Warnings

January 03, 2022

Seller of Wormwood, Aloe Supplement Warned by FDA

On December 7, 2021, the FDA issued a warning letter for Western Herb Products, Inc.

Recalls & Warnings

November 14, 2012

Mushroom Supplement Manufacturer Warned For Drug Claims and Adulteration

On October 18, 2012, the FDA issued a warning letter to Mushroom Wisdom, Inc. following a facility inspection and product label review which found the dietary supplements Amyloban 3399 From Lion's Mane, Grifron Maitake, and Super Shiitake to be promoted as drugs.

News Release

February 25, 2024

Top-rated Vitamin and Supplement Brands and Merchants for 2024 Based on Consumer Satisfaction

White Plains, New York, February 25, 2024 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on over 10,000 responses collected in November/December 2023.

Recalls & Warnings

December 22, 2021

FDA Warns Seller of Liquid Magnesium, B-12, Berberine & More

On December 9, 2021, the FDA issued a warning letter to Wholly Liquid Nutritional Supplements LLC because it found statements on the company's website and social media about its products, including SpiroLaze, BioLaze, LiquiLaurin, VIT-B12, DeStress, and Omega Plus, to be ...

Recalls & Warnings

June 02, 2022

Walmart Inc. Recalls Joint Supplements With Omega-3, Glucosamine & Curcumin

On May 28, 2022, Walmart Inc. issued a voluntary recall of all lots of Artri Ajo King Joint Supplements after FDA laboratory analysis found the presence of undeclared diclofenac.

News Release

February 25, 2023

Top-rated Vitamin and Supplement Brands and Merchants for 2023 Based on Consumer Satisfaction

White Plains, New York, February 25, 2023 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 8,600 responses collected in November/December 2022.

News Release

October 06, 2022

Lion’s Mane and Chaga Supplement Labels May Mislead, According to ConsumerLab Tests

  White Plains, New York, October 6, 2022 — Lion’s mane and chaga supplements are often promoted to improve memory and mood, boost the immune system, and a range of other health benefits.

News Release

August 22, 2019

Best Reishi Mushroom Supplements Identified by ConsumerLab

White Plains, New York, August 22, 2019 — Reishi mushroom supplements are promoted for many uses, from strengthening the immune system and lowering blood sugar, to improving cardiovascular health and reducing cancerous tumors.

Recalls & Warnings

February 22, 2024

Pacific BioLogic Co. Warned by FDA for Manufacturing Violations

On December 21, 2023, the FDA issued a Warning Letter to Curtis Jacquot, dba Pacific BioLogic Co.

Recalls & Warnings

December 02, 2020

Seller of Vitamin C, Elderberry, Silver, and More Warned for COVID-19 Claims

On November 10, 2020, the FDA issued a warning letter to Sage Woman Herbs, Ltd.

Recalls & Warnings

April 02, 2021

FDA Warns Sellers of Prostate, Reishi, Immune Products, and More

On March 16, 2021, the FDA issued warning letters to two companies following reviews of their websites which found statements made about the companies' products to be drug claims.

Recalls & Warnings

May 23, 2020

FTC Warns 50 More Companies for Coronavirus Claims

On May 21, 2020, the FTC announced that it sent warning letters to 50 companies for selling products such as herbal products, immune system boosters, and vitamin C, with unsupported claims that they can treat coronavirus (COVID-19).

Recalls & Warnings

March 30, 2019

FDA Warns Seller of Reishi, Joint Supplements, Ginseng & More for Pesticides, Other Violations

On March 12, 2019, the FDA issued a warning letter to Yanqing "Michael" Li and Chang Su, owners of the website http://www.woohoonatural.

Recalls & Warnings

May 30, 2017

Seller of Vitamin C, Calcium, Mushroom Supplements and More Warned for Manufacturing Violations

On May 12, 2017 the FDA issued a warning letter to VitaPurity Corporatio.

Recalls & Warnings

February 17, 2018

FDA Warns Seller Reishi Mushroom Supplements

On February 7, 2018, the FDA issued a warning letter to Reishi D. International, Inc., following a facility inspection which found the company's Reishi D.

Recalls & Warnings

June 07, 2013

Maker of Colloidal Silver and Mushroom Extract Supplements Warned For Manufacturing Violations and Drug Claims

On May 2, 2013, the FDA issued a warning letter to Earthborn Products, Inc.

Recalls & Warnings

August 30, 2012

FDA Warns of Medical Claims Made For Numerous Chinese Herbal Products

On August 15, 2012, the FDA warned Dragon Herbs that promotional statements made on the company's website constitute drug claims for twenty herbal products, including CardioPro 2000, Cordyceps, Duanwood Reishi, Gynostemma, Ginseng and Astragalus Combination, Dang Gui and Gelatin, Sweet Relief, ...

Recalls & Warnings

April 26, 2013

Seller of Immune, Cholesterol, Liver and Blood Sugar Products Warned For Drug Claims

On March 20, 2013, the FDA issued a warning letter to Birkdale Medicinals LLC, following a review of the company's website which found statements made about Birkdale products, including Immune Response 247, Cholestat, Silymarin 81 and LevelStat, to be drug claims.