Reviews and Information for Lion's Mane (Mushroom)
Lion's Mane and Chaga Mushroom Supplements
Our Review gives you our Top Picks for the best lion's mane and chaga supplements and food products. See which brands passed our tests and learn more about uses, side effects, risks, health benefits, cost, and quality.
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Clinical Update
12/27/2024
Lion's Mane Reformulated
Swanson Full Spectrum Lion's Mane Mushroom appears to have been reformulated, possibly in response to ConsumerLab's findings. Get the details in our Lion's Mane and Chaga Supplements Review, which includes our Top Picks for lion's mane and chaga and explains what to look for on labels to avoid being misled.
CL Answer
What supplements should I stop taking before surgery?
Info on which supplements to avoid before surgery due to increased risk of bleeding or interference with anesthesia.

Product Review
B Vitamin Supplements Review (B Complexes, B6, B12, Biotin, Folate, Niacin, Riboflavin & More)
See Our Top Picks and Which 5 Failed Testing

Clinical Update
6/27/2025
Is Mushroom Coffee Healthier?
Mushroom coffee is promoted as healthier than regular coffee, but does it really contain more nutrients? Find out in the What It Is section of our Lion's Mane and Chaga Supplements Review, which includes our Top Picks for lion’s mane and chaga, as well as reviews of MUD/WTR and Four Sigmatic Instant Coffee Mix.
Product Review
Reishi Mushroom Supplements Review
Find the Best Reishi Mushroom Supplement. See How Reishi Supplements Differ.

CL Answer
Does ergothioneine help prevent age-related problems such as impaired cognition, Alzheimer’s disease, Parkinson’s disease or cataract, and is it safe?
Learn about ergothioneine and its potential use for cognitive impairment, dementia, Alzheimer's disease, Parkinson's disease, cataract, or kidney disease, as well as its safety and cost of supplements containing this ingredient.

Clinical Update
10/24/2024
Avoiding Counterfeit Mushrooms
A mushroom supplement maker has won a lawsuit against a company allegedly selling counterfeit versions of its products, including on Amazon. Details are in our article: Where to Safely Buy Real Vitamins and Supplements Online.
For ConsumerLab’s test results for mushroom supplements, see our Reishi Mushroom Supplements Review and our Lion's Mane and Chaga Supplements Review.
Clinical Update
12/09/2022
Mushroom Supplement Interaction
Can mushroom supplements interfere with tests for fungal infections? Find out in the Concerns and Cautions section of the Lion's Mane and Chaga Supplements Review as well as in our Reishi Supplements Review.
CL Answer
What are the health effects of turkey tail mushroom and is it safe?
Learn about the possible health effects of turkey tail mushroom, including its use as adjuvant treatment for cancer and for boosting immune function, plus get information about possible side effects and find out why ConsumerLab has not yet tested turkey tail products.

Clinical Update
5/05/2023
Counterfeit Supplements
Counterfeit versions of psyllium, a multivitamin, magnesium, and eight other types of supplements from a major brand have been sold online. Details and how to avoid this are in our Psyllium Supplements Review.
A popular brand of mushroom supplements has also reported counterfeit versions of its products. Details and how to avoid this are in our Lion's Mane Review.
Clinical Update
2/14/2023
Does Lion's Mane Boost Cognition?
Did taking lion’s mane boost cognitive function in healthy, young people in a recent study? Find out in our Lion's Mane Review, which also discusses lion’s mane’s effects on older people and identifies our Top Pick among Lion's Mane supplements.
Also, see our article about other supplements for brain function.
CL Answer
With herbal supplements, what is the difference between root powder and root extract? Does it matter?
Learn more about the different forms of herbal supplements, including aloe, boswellia, ginkgo, green tea, and milk thistle.

Clinical Update
12/23/2023
Lion’s Mane for Cognition?
Did taking lion’s mane before a cognitive test improve results? Find out what a recent study showed in the Cognitive function and memory section of our Lion’s Mane and Chaga Supplements Review, which includes our Top Picks among lion's mane supplements.
Also see: Do any supplements, foods or lifestyle modifications help with brain function, like memory and cognition?
Clinical Update
4/17/2025
Lion’s Mane for Cognition?
Did taking lion’s mane improve cognition or mood in a recent study? Find out in the What It Does section of our Lion's Mane and Chaga Supplements Review, which includes our Top Pick for lion’s mane.
Clinical Update
8/26/2022
Lion's Mane for Depression, Anxiety, Gut Health
Does lion's mane (promoted for memory) help with depression, anxiety or gut health? See our article about lion's mane.
Clinical Update
6/17/2022
Lion’s Mane for Neuropathy?
Does supplementation with lion’s mane reduce symptoms of neuropathy? Find out what evidence suggests in our article about lion’s mane.
Also see our CL Answer about supplements for nerve pain.
Clinical Update
4/21/2025
Something to Watch Out for With Chaga
If you are looking to purchase a chaga supplement, you may want to avoid a certain type of chaga, according to a recent study. For details, see the ConsumerTips section of our Lion's Mane and Chaga Supplements Review, which includes our Top Picks for chaga as well as for lion’s mane.
News Release
February 25, 2025
Top-rated Vitamin and Supplement Brands and Merchants for 2025 Based on Consumer Satisfaction
White Plains, New York, February 25, 2025 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on over 8,400 responses collected in November/December 2024.
Recalls & Warnings
June 18, 2025
Comvita Manuka Honey + Reishi and Lion's Mane Products Recalled
On May 23, 2025, Comvita USA INC recalled certain Comvita branded Manuka Honey + Reishi, Comvita branded Manuka Honey + Cordyceps for Energy, and Comvita branded Manuka Honey + Lion's Mane for Focus products due to a leaking induction seal on the packaging.
CL Answer
Is it safe to drink coffee regularly? Does drinking coffee increase or decrease the risk of cancer?
Learn more about coffee, its safety, if it's good for you, and if it impacts your risk of cancer.

Recalls & Warnings
January 04, 2024
Lone Star Botanicals Warned by FDA for Manufacturing Violations
On November 26, 2023, the FDA issued a Warning Letter to Lone Star Botanicals, Inc.
Recalls & Warnings
June 17, 2024
Do Not Consume Diamond Shruumz Products, Warns CDC and FDA
On June 12, 2024, the Center for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and America’s Poison Centers warned consumers not to buy or consume Diamond Shruumz chocolate bars, cones, and gummies.
Recalls & Warnings
September 24, 2024
Manufacturer of Mushroom Gummies Warned by FDA for Violations
On August 13, 2024, the FDA issued a Warning Letter to Restorative Botanicals, LLC, following an inspection of the company’s facility found the company’s products, including its My GUT Shrooms Gummies and My IMMUNE Shrooms Capsules, to be adulterated because they were prepared, ...
Recalls & Warnings
September 14, 2021
Seller of Lion's Mane, Other Mushroom Supplements Warned by FDA
On July 20, 2021, the FDA issued a warning letter to Brilliant Enterprises LLC because it found statements made on the company's website and social media about mushroom supplements, including Lion's Mane, BoomChaga, CordaCex, and LVL:MAX to be drug claims.
CL Answer
Does AHCC or active hexose correlated compound have anticancer or antiviral benefits, and is it safe?
Learn about AHCC and active hexose correlated compound, including whether these compounds are beneficial for liver, pancreatic, or prostate cancer, chemotherapy-related side effects, or the flu. Also, find out if AHCC or active hexose correlated compound are safe.

Recalls & Warnings
December 09, 2021
FDA Warns Seller of Curcumin, Lion's Mane, Quercetin & More
On November 9, 2021, the FDA issued a warning letter to Synaptent, LLC because it found statements on the company's website about its products, including Berberine HCL, Curcumin, Lion's Man, Milk Thistle, Quercetin, Boswellia Serrata Extract, and Garlic Extract to be ...
Recalls & Warnings
July 17, 2023
Seller of Ashwagandha, Lion’s Mane & Other Supplements Warned for Manufacturing Violations
On March 17, 2023, the FDA issued a warning letter to Brand Packaging Group, Inc. after FDA inspection of the company’s facility found products to be adulterated because they were prepared, packed, or held under conditions that do not meet Current Good Manufacturing Practices (CGMP).
Recalls & Warnings
February 02, 2021
FDA Warns Seller of Reishi Mushroom Supplements
On January 6, 2021, the FDA issued a warning letter to Entia Biosciences, Inc following a review of the company's website, which found statements made about the company's products Lion's Mane - All Natural Supplement, Antrodia Mushroom Powder, Maitake Mushroom Powder, Reishi ...
News Release
February 26, 2024
Latest ConsumerLab Survey Shows Growth in Popularity of Magnesium and Several Smaller Supplements
White Plains, New York, February 26, 2024 — A recent survey of more than 10,000 people who regularly use dietary supplements shows that supplements that experienced the greatest absolute growth in popularity during 2023 were pregnenolone (+7.5 percentage points), magnesium (+4.8 pts), berberine (+4.
Clinical Update
10/12/2021
Mushrooms and Blood Sugar
Find out if supplementing with reishi or oyster mushrooms helps with blood sugar control. See what the latest research showed in our Reishi Mushroom Supplements Review.
Clinical Update
10/12/2021
Mushrooms and Gut Bacteria
Do mushroom powders have beneficial effects on gut bacteria? See what a preliminary study found in the What It Does section our Reishi Mushroom Supplements Review.
Clinical Update
4/19/2022
Shiitake Mushroom Rash
If not properly prepared, shiitake mushrooms can cause a distinctive skin rash, as noted in recent reports. The details are in our article about ergothioneine, a potentially beneficial compound found in shiitake and other mushrooms.
Clinical Update
6/21/2022
Muscle Weakness from Mushrooms?
Be aware that, although rare, mushrooms and mushroom supplements may trigger a rare autoimmune reaction resulting in muscle pain or weakness. Get the details in the Concerns and Cautions section of our Reishi Supplements Review.
Clinical Update
1/14/2022
Liver Injury With Reishi
Although very rare, liver injury has occurred in people taking reishi mushroom. Learn more, including details of a recent report, in the Concerns and Cautions section of our Reishi Mushroom Supplements Review.
Clinical Update
7/01/2022
Mushroom Compound for HPV?
Active hexose correlated complex (AHCC), produced from mushrooms, may help clear persistent, high-risk human papilloma virus (HPV) infection in women, according to a recent study. Get the details in the Antiviral Effects section of our CL Answer about AHCC.
Clinical Update
4/15/2022
Mushrooms for Lowering Cholesterol?
The beta-glucan in oats can help lower elevated levels of cholesterol, but can the beta-glucan in mushrooms do the same? Find out in our article about Supplements and Foods for Lowering Cholesterol.
Clinical Update
12/05/2023
Ergothioneine in Mushrooms
Ergothioneine, a potentially beneficial compound in mushrooms, was found to be reduced by certain types of food preparation. Get the details in our article about ergothioneine.
Clinical Update
12/09/2024
Vitamin D From Mushrooms?
Specially-grown mushrooms can be a good source of vitamin D, but a recent study showed that cooking may significantly decrease levels, as discussed in the Getting Vitamin D From Foods section of our Vitamin D Supplements Review.
Also learn about getting vitamin D from other foods, and see our Top Picks among vitamin D supplements.
Recalls & Warnings
December 15, 2020
Mushroom Supplement Seller Warned for Drug Claims
On December 4, 2020, the FDA issued a warning letter to Desert Alchemist LLC following a review of the company's website, social media, and Etsy.com store (www.etsy.
Recalls & Warnings
February 06, 2023
FDA Warns Companies Promoting Products to Treat Monkeypox, COVID-19, & Other Viruses
On January 30, 2023, the FDA issued a warning letter to four companies following review of the company websites, which found statements about company products to be drug claims because they were promoted to mitigate, prevent, treat, diagnose, or cure viruses such as monkeypox.
Clinical Update
11/21/2023
Vinegar or Baking Soda for Washing Produce?
Is vinegar or baking soda more effective than water for cleaning fruits and vegetables? See what research suggests in our article about fruit and veggie washes.
Also see which method experts recommend for cleaning mushrooms.
Clinical Update
10/28/2024
Concern with Cordyceps
If you use the mushroom, cordyceps (Cordyceps sinensis), be aware of widespread cheapening with material that is not cordyceps. Learn what to look for on labels, in the Cordyceps section of our article about testosterone boosters.
Recalls & Warnings
July 19, 2023
FDA Warns Seller of Sleepy Time Products and Honey Herbal Syrups for Manufacturing Violations
On June 28, 2023, the FDA issued a warning letter to Eden’s Answers, Inc. after an inspection of the company’s facility found products to be adulterated because they were prepared, packed, or held under conditions that do not meet Current Good Manufacturing Practices (CGMP).
Recalls & Warnings
January 03, 2022
Seller of Wormwood, Aloe Supplement Warned by FDA
On December 7, 2021, the FDA issued a warning letter for Western Herb Products, Inc.
Recalls & Warnings
November 14, 2012
Mushroom Supplement Manufacturer Warned For Drug Claims and Adulteration
On October 18, 2012, the FDA issued a warning letter to Mushroom Wisdom, Inc. following a facility inspection and product label review which found the dietary supplements Amyloban 3399 From Lion's Mane, Grifron Maitake, and Super Shiitake to be promoted as drugs.
News Release
February 25, 2024
Top-rated Vitamin and Supplement Brands and Merchants for 2024 Based on Consumer Satisfaction
White Plains, New York, February 25, 2024 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on over 10,000 responses collected in November/December 2023.
Recalls & Warnings
December 22, 2021
FDA Warns Seller of Liquid Magnesium, B-12, Berberine & More
On December 9, 2021, the FDA issued a warning letter to Wholly Liquid Nutritional Supplements LLC because it found statements on the company's website and social media about its products, including SpiroLaze, BioLaze, LiquiLaurin, VIT-B12, DeStress, and Omega Plus, to be ...
Recalls & Warnings
June 02, 2022
Walmart Inc. Recalls Joint Supplements With Omega-3, Glucosamine & Curcumin
On May 28, 2022, Walmart Inc. issued a voluntary recall of all lots of Artri Ajo King Joint Supplements after FDA laboratory analysis found the presence of undeclared diclofenac.
News Release
February 25, 2023
Top-rated Vitamin and Supplement Brands and Merchants for 2023 Based on Consumer Satisfaction
White Plains, New York, February 25, 2023 — Each year, ConsumerLab.com surveys its free e-newsletter subscribers about the vitamins and supplements that they use. The results below are based on 8,600 responses collected in November/December 2022.
News Release
October 06, 2022
Lion’s Mane and Chaga Supplement Labels May Mislead, According to ConsumerLab Tests
White Plains, New York, October 6, 2022 — Lion’s mane and chaga supplements are often promoted to improve memory and mood, boost the immune system, and a range of other health benefits.
News Release
August 22, 2019
Best Reishi Mushroom Supplements Identified by ConsumerLab
White Plains, New York, August 22, 2019 — Reishi mushroom supplements are promoted for many uses, from strengthening the immune system and lowering blood sugar, to improving cardiovascular health and reducing cancerous tumors.
Recalls & Warnings
February 22, 2024
Pacific BioLogic Co. Warned by FDA for Manufacturing Violations
On December 21, 2023, the FDA issued a Warning Letter to Curtis Jacquot, dba Pacific BioLogic Co.
Recalls & Warnings
December 02, 2020
Seller of Vitamin C, Elderberry, Silver, and More Warned for COVID-19 Claims
On November 10, 2020, the FDA issued a warning letter to Sage Woman Herbs, Ltd.
Recalls & Warnings
April 02, 2021
FDA Warns Sellers of Prostate, Reishi, Immune Products, and More
On March 16, 2021, the FDA issued warning letters to two companies following reviews of their websites which found statements made about the companies' products to be drug claims.
Recalls & Warnings
May 23, 2020
FTC Warns 50 More Companies for Coronavirus Claims
On May 21, 2020, the FTC announced that it sent warning letters to 50 companies for selling products such as herbal products, immune system boosters, and vitamin C, with unsupported claims that they can treat coronavirus (COVID-19).
Recalls & Warnings
March 30, 2019
FDA Warns Seller of Reishi, Joint Supplements, Ginseng & More for Pesticides, Other Violations
On March 12, 2019, the FDA issued a warning letter to Yanqing "Michael" Li and Chang Su, owners of the website http://www.woohoonatural.
Recalls & Warnings
May 30, 2017
Seller of Vitamin C, Calcium, Mushroom Supplements and More Warned for Manufacturing Violations
On May 12, 2017 the FDA issued a warning letter to VitaPurity Corporatio.
Recalls & Warnings
February 17, 2018
FDA Warns Seller Reishi Mushroom Supplements
On February 7, 2018, the FDA issued a warning letter to Reishi D. International, Inc., following a facility inspection which found the company's Reishi D.
Recalls & Warnings
June 07, 2013
Maker of Colloidal Silver and Mushroom Extract Supplements Warned For Manufacturing Violations and Drug Claims
On May 2, 2013, the FDA issued a warning letter to Earthborn Products, Inc.
Recalls & Warnings
August 30, 2012
FDA Warns of Medical Claims Made For Numerous Chinese Herbal Products
On August 15, 2012, the FDA warned Dragon Herbs that promotional statements made on the company's website constitute drug claims for twenty herbal products, including CardioPro 2000, Cordyceps, Duanwood Reishi, Gynostemma, Ginseng and Astragalus Combination, Dang Gui and Gelatin, Sweet Relief, ...
Recalls & Warnings
April 26, 2013
Seller of Immune, Cholesterol, Liver and Blood Sugar Products Warned For Drug Claims
On March 20, 2013, the FDA issued a warning letter to Birkdale Medicinals LLC, following a review of the company's website which found statements made about Birkdale products, including Immune Response 247, Cholestat, Silymarin 81 and LevelStat, to be drug claims.