Can fisetin, also called Cognisetin and Novusetin, really improve memory or slow aging?

Latest Update

Fisetin for Aging?

Written by Tod Cooperman, M.D.

Latest Update May 21, 2026 ⓘ

Fisetin Supplements on Wooden Plate with Strawberries

Answer:

Fisetin is a flavonol found in plants such as the Japanese fruit wax tree (Rhus succedanea), as well as in small amounts in foods such as strawberries, tomatoes, and onions. It has been sold as the branded ingredient Cognisetin, by Cyvex Nutrition, and is now sold by the same company as Novusetin.

Fisetin is promoted for improving brain health, cognition and memory, as well as for extending lifespan, targeting cancer, lessening complications of type 1 diabetes, and lowering blood pressure.

Sign in as a member to learn whether clinical research supports the safety and effectiveness of fisetin for these uses.

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